Biotics Research

Why you may need Dysbiocide: Dysbiosis has historically been defined as an imbalance of gastrointestinal microflora, indicating an increase in abnormal flora with a coinciding decrease in normal flora, and an increase in pathogenic organisms and yeast in the lower bowel.The definition has since evolved to what Dr.Alex Vasquez describes generally as“A relationship of non-acute, non-infectious host microorganisms interactions that adversely affects the human host.” There are numerous correlations including poor diet, physical and/or psychological stress, and overuse of antibiotics to name a few. For instance, psychological stress has been demonstrated to decrease the level of secretory IgA, resulting in decreased mucosal immunity. Why we recommend Dysbiocide: Selected botanicals are well recognized in promoting the health of damaged intestinal tissue resulting predominately from dysbiosis. For example, the active principals of Stemona sessilifolia root exert antifungal and antibacterial properties. Artimisia absinthium, whose properties are at least partially attributed to its α-santonin content, is a potent, rapidly acting herb with actions that are cholagogue (inducing bile flow), and therefore digestive, as well as healing in nature.This is attributed to its essential oils and amoroids, which also possess antimicrobial and antiparasitic properties.Artemisia has also been shown to stimulate bitter receptors. Research has correlated the ingestion of bitter stimuli with an initiation of cellular and molecular responses in the endocrine cells of the GI tract. Anethum graveolens seed is an aromatic herb know for its calming effect on the autonomic nervous and digestive systems, as well as having carminative and stomachic properties. It also provides an essential oil containing corvone, limonene and α-phellandrene which possess potent activity against bacteria, fungi and molds. Hedyotis diffusa is widely used in traditional Chinese medicine.Active principles include anthraquinones, iridoid glucosides, triterpenoids and flavonoids. Hedyotis has been demonstrated to possess antioxidant, hepatoprotective and neuroprotective properties. By virtue of its combination of these and other Eastern and Western herbs, Dysbiocide® affords a broad effect, providing an unfriendly environment for undesirable intestinal organisms.

Intenzyme Forte™ is a broad spectrum proteolytic enzyme formulation, containing pancreatin, bromelain, papain, lipase, amylase, trypsin and alpha chymotrypsin. It may be utilized to support numerous protein metabolism pathways. Proteolytic enzymes are capable of exerting influence over a wide variety of physiological and biochemical processes. The benefits of Intenzyme Forte include its effect on muscle soreness and discomfort due to overexertion, the support of hormone processing, as well as providing support for healthy digestive, immune and circulatory functions. Why you may need Intenzyme ForteTM: Health researchers are continually discovering that inflammation and its effects are at the root of many health problems. In fact, most chronic health challenges involve some degree of inflammation. But acknowledging inflammation and addressing it are two very different entities. Since inflammation can be caused from such a wide variety of factors – everything from physical wear and tear, diet, environmental factors, genetics, and even local or systemic allergies, it can be difficult to find an easy way to address it. Intenzyme Forte is a potent source of both plant and animal based enzymes that are an effective combination to break down the aberrant proteins associated with inflammation, hence the term “proteolytic enzymes”. For example, proteolytic enzymes provide all-natural and highly effective support for systemic or localized inflammation and discomfort such as muscle soreness.The key, however, is that in order to benefit from enzymes proteolytic actions; it must be taken on an empty stomach. If taken with food, the enzyme will work as a digestive aid instead. Why your healthcare practitioner recommends Intenzyme ForteTM: Intenzyme ForteTM is a broad spectrum nutritional supplement capable of exerting influence over a variety of physiological and biochemical mechanisms, including: inflammatory processes, numerous pathways of protein metabolism, hormone processing, digestive processes, food sensitivities, immune system support, and healthy circulatory system support. Intenzyme ForteTM also has the ability to break down mucous secretions as well. For over 30 years, thousands of healthcare practitioners have relied on the safe, effective, and reliable results that Intenzyme ForteTM has to offer. As always, you can count on Biotics Research to offer superior nutritional products that supply “The Best of Science and Nature”.

HOLIDAY SPECIAL GIFT IDEA - SAVE $5.00 PER BOTTLE Herbs, spices and botanical preparations often exhibit antimicrobial properties due to a wide array of terpenoid and polyphenolic compounds. Indeed, culinary herbs have long been used to control pests and food-borne yeasts and molds in the context of food safety. FC-CidalTM contains the herbal preparations French tarragon (Artemisia dracunculus), Stinging Nettle extract (Urtica dioica), Indian tinospora (Tinospora cordifolia), Horsetail (Equisetum arvense), Olive (Olea europaea), Thyme ( Thymus vulgaris) and Pau D’ Arco ( Tabebuia impetiginosa). Artemisia dracunculus (Tarragon) A culinary herb yielding a characteristic aromatic oil, Artemisia yields a complex mixture of almost 50 different components. Its most potent constituents include anisaldehyde, paracymene, eugenol, liminene, linalool, menthol, cisocimene, alpha phellandrene, alpha pinene and beta pinene. The essential oil of Artemisia showed antagonistic activity toward the growth of E. coli, Pseudomonas aeruginosa, Staphyloccocus aureus, Streptococcus faecalis and Yersinia in vitro. Urtica dioica (Stinging Nettle Extract) Urtica dioica, often called common nettle, stinging nettle or nettle leaf, is native to Europe, Asia, northern Africa, and western North America. Urtica dioica was studied on 16 skin and wound infections and was found to possess qualities to promote healing and bacterial homeostasis. In another interesting study, the extract from Urtica dioica demonstrated antagonistic activity toward specific biofilm production (SBF) in Escherichia coli BW25113. Tinaspora cordifolia (Guduchi) This herb has also been used traditionally in India. It contains bitter substances, giloin (a glycoside), gilenin, gilosterol and tinosporine. Ethanol extracts of T. cordifolia, in combination with several other herbs, had a minimal inhibitory concentration (MIC) of 1 mg/ml when tested in vitro against Entamoeba histolytica. Using an in vitro assay system with Candida albicans as the test organism, the activity of rat macrophages was increased by the administration of T. cordifolia at a level of 100 mg/kg. It also induces production of interleukin (IL)-1, IL-6, IL-12, IL-18, interferon-gamma, tumor necrosis factor (TNF)-alpha and nonocyte chemoattractant protein (MCP)-1. Equisetum arvense (Horsetail) In addition to a high percentage of silicates, horsetail contains a variety of polyphenols, such as agigenin and luteolin glycosides. These flavones are typical of American and Asian species, but not the European Equisetum species. This herb also contains quercetin, and more unusual polyphenolics, such as genkwanin and progenkwanin glycosides. Horsetail also contains sterols, such as beta sitosterol and campestrol, as primary sterol constituents. Olea europaea (Olive leaf ) Various flavonoids and their glycosides have been isolated from olives and olive leaves, such as apigenin, luteolin, rutin and quercetin. Oleuropein, a bitter principle of olives, is a glucoside and phenolic ester of elenolate, which is a multifunctional monoterpene. In vitro studies demonstrated that elenolate possesses antiviral properties. In a laboratory test, olive leaf water (0.66% w/v) extract killed almost all bacteria tested within three hours, and scanning electron microscopic observations of Escherichia coli cells exposed to only 0.6% (w/v) olive leaf extract showed complete destruction. Thymus vulgaris (Thyme) An aromatic culinary herb, thyme has long been used as a seasoning and food preservative. Thyme contains 1-2.5% as an aromatic oil enriched in monoterpenes. Thymol content of thyme oil can be 30 to 70% and carvacrol content ranges between3 and 15%. P-cymene, limonene and other terpenes are minor constituents. Thymol supports healthy microbial diversity. Volatile constituents of the aromatic oil of thyme influenced the growth of seven different Gram-positive and Gram-negative bacteria. Thyme also contains several polyphenolic compounds, such as eriodictyoland polyphenolic biphenyls, that exhibit potent antioxidant activity. Additional studies of lipid peroxidation in egg yolk, chicken liver, and muscle from mature chickens highlighted that the essential oil of thyme acted as a strong antioxidant in all of these systems. The tricyclic derivative of lapachol and β-lapachone functions as an activator of the DNA unwinding enzyme, topoisomerase I, which is required for DNA repair. Among the naphthoquinones, β-lapachone was found to be the most effective in fostering the growth of healthy bacteria. β-lapachone also inhibited the expression of iNOS, proinflammatory cytokines, and MMPs (MMP-3, MMP-8, MMP-9) at mRNA and protein levels in LPS-stimulated microglia, which suggests its support of inflammation pathways. The antioxidant effects of β-LAP appear to be related with the increase of HO-1 and NQO1 via the Nrf2/antioxidant response element (ARE) pathway and/or the PKA pathway. NOTE: All of the above statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Why you may need A.D.P.®: Modern researchers frequently turn to spices and herbs that have been used for centuries to unlock health benefits. Long before the advent of refrigeration, herbs and culinary spices were recognized to slow food spoilage, showing the natural antimicrobial properties at work. Increasingly, interest in identifying the active constituents of the essential oils in these everyday flavorings has grown. One well‐researched herb whose essential oils have been shown to have health benefits is oil of oregano. Oil of oregano contains several phenolic compounds including carvacrol and thymol, the two with greatest biological activity, and antioxidants. A.D.P.® has been proven effective against yeast and parasites (Patent #5,955,086).(1,2) Further research indicates the active components of oil of oregano adversely affect the ability of various microbial organisms to reproduce.(3) Why we recommend A.D.P.®: While people have relied on the health‐promoting properties of oregano oil for hundreds of years, Biotics Research Corporation has dramatically improved its delivery system.(2) With its proven effective, patented formula, A.D.P.® can deliver the emulsified form oil of oregano throughout the digestive tract, where it supports the body’s response to undesirable intestinal organisms. Furthermore, oil of oregano is mostly absorbed in one area of the small intestine, thus limiting the efficacy of a non‐gradual released product in reaching key areas of the digestive tract.While many commercially available oregano oil products vary in potency, and can be difficult to take due to unpalatable taste, A.D.P.® supplies a standardized extract of oregano oil (50mg) in a gradual release mechanism, ensuring the ease of dosing and maximum delivery. A.D.P.® is not recommended for pregnant or lactating women. 1. Stiles JC, Sparks B, Ronzio RA.The Inhibition of Candida albicans by oregano. J Applied Nutrition. 1995 47(4):96-102.2. Force M, Sparks WS, Ronzio RA, Inhibition of Enteric Parasites by Emulsified Oil of Oregano in vivo. Phytother, Res. 14, 213-214 (2000)3. Friedman M. Chemistry and multibeneficial bioactivities of carvacrol (4-isopropyl-2-methylphenol), a component of essential oils produced by aromatic plants and spices. J Agric Food Chem. 2014 Aug 6;62(31):7652-70. doi: 10.1021/jf5023862. Epub 2014 Jul 24.

Why you may need Cytozyme-PT/HPTTM: The Pituitary Gland (PT) is divided into the anterior and posterior pituitary. It is often referred to as the master gland, as it secretes a battery of hormones that collectively influence all cells, and affect virtually all physiologic processes in the body. For example, the anterior pituitary secretes thyroid stimulating hormone (TSH) and growth hormone, while the posterior pituitary secretes the hormones vasopressin, also called anti-diuretic hormone, and oxytocin. The hypothalamus (HPT), the power house behind the pituitary, secretes hormones that strictly control secretion of hormones from the anterior pituitary. Located below the thalamus (brain area that relays sensory information) and above the pituitary gland and brain stem, the hypothalamus plays a significant role in the endocrine system. Hypothalamic hormones are referred to as “releasing hormones and inhibiting hormones”, reflecting their influence on anterior pituitary hormones. An endocrine feedback system involving the pituitary and the hypothalamus controls the secretion of thyroid hormones (T3 and T4) by the thyroid gland, resulting from the production of TSH by the pituitary. The hypothalamus is often noted as the link between the endocrine and nervous systems. Why we recommend Cytozyme-PT/HPTTM from Biotics Research: Cytozyme-PT/HPTTM supplies a proprietary source of young lamb pituitary/hypothalamus concentrate. Your healthcare provider may recommend Cytozyme-PT/HPTTM if they determine that you may benefit from targeted, specific glandular support. Cytozyme-PT/HPTTM; another example of Biotics Research bringing you “The Best of Science and Nature.”

Pneuma-Zyme™ is a source of neonatal bovine lung tissue with additional nutritional factors to support lung healing and repair.  Pneuma-Zyme is known to support lung function. It is used with upper respiratory problems, i.e., asthma, emphysema, smoker’s cough, pulmonary involvement of adrenal and cardiac stress, environmental allergy, and sensitivity. Use two tablets three times a day. Pneuma-Zyme works well for upper respiratory problems such as infection, asthma, emphysema, food or environmental sensitivity, or any number of other problems that result in upper respiratory congestion or degeneration.* Most upper respiratory problems, such as asthma and emphysema, will involve adrenal dysfunction. When adrenal dysfunction is present, consider using Cytozyme-AD (hypoadrenia) or ADHS (hyperadrenia) with Pneuma-Zyme.*

Bio-D-Mulsion Forte® supplies 2,000 IU per drop of vitamin D3 as a micro-emulsion for enhanced absorption and utilization, which is particularly important for those with malabsorption conditions. Published clinical studies have demonstrated significant improvements in 25(OH)D concentrations (202% increase) in as little as six weeks after beginning supplementation with Bio-D-Mulsion Forte. The majority of people in the United States do not synthesize sufficient vitamin D in order to meet physiological requirements. 

A Somnotropic Formula • Supports Onset, Duration and Quality of Sleep • Induces Calming Brainwave Activity Good quality, uninterrupted sleep is integral to achieving optimal health. Without it, we fall prey to a cascade of physiologic dysfunction that results in increased body mass index (BMI), a decline in cognitive performance1, increased risk of heart disease and diabetes, hormonal imbalances, immune system dysfunction, depression and anxiety, and even vitamin D deficiency. Stages of Sleep Sleep is a complex phenomenon constituted by two types of sleep patterns: non-REM (also called Slow Wave Sleep) and REM. In an ideal sleep pattern, a person experiences stages of sleep in non-REM and REM phases. Slow Wave Sleep (non-REM) presents as a high voltage slow wave electroencephalographic pattern (alpha and delta waves), while REM sleep exhibits a low voltage fast wave pattern (theta wave) accompanied by eye movement. If either phase is disrupted, or sleep disturbance results. Although stages of sleep accompanied by calming brainwave activity is the natural circadian rhythm, 70% of American adults report that they obtain insufficient sleep at least one night a month, and 11% report insufficient sleep every night. It is estimated that sleep-related problems affect 50 to 70 million Americans of all ages and socioeconomic classes.2 Because sleep deprivation is linked to increased health risk, sleeplessness has become a public health concern. Root of Sleeplessness At the root of impaired sleep quality may be a number of underlying issues. Neurochemical balance is key to achieving optimal sleep patterns. However, the following may be contributing to a neurochemical imbalance: • Imbalance in neurotransmitter function (GABA, serotonin and dopamine) • Lack of precursors to make neurotransmitters • Excess glutamate • HPA-Axis Dysregulation • Anxiety and stress • Environmental factors • Electromagnetic fields Anxiety can be an instigator for sleepless nights and seems to be the result of an imbalance in neurotransmitter (GABA, serotonin and dopamine) function. Excess glutamate, the main excitatory neurotransmitter in the brain, results in low gamma-aminobutyric acid (GABA), essential for limiting the excitation of neurotransmitters and fundamental for good-quality sleep. Electromagnetic fields and blue light also play a role in decreased melatonin production,3 necessary for normal sleep cycles. Stress, common to 79% of all Americans4, can yield excess cortisol or insufficient cortisol production, both of which tip the hormonal balance to wakefulness in the night. Although each person’s neurochemistry is unique, Alpha-Theta Ultra PM is a somnotropic formula that incorporates key nutrients recognized to induce calming brainwave activity and promote the onset and duration of high-quality sleep for most people by supporting GABA receptor function, and healthy levels of serotonin and dopamine. Well-researched anxiolytic botanicals and nutrients include L-theanine (Suntheanine®), Baikal Skullcap (Scutellaria baicalensis), Lemon Balm (Melissa officinalis), Passionflower (Passiflora incarnata), 5-HTP, and Melatonin. L-Theanine (Increases GABA and Dopamine Levels) L-theanine (γ-glutamylethylamide) is an amino acid found in green tea. A derivative of glutamic acid, it is one of the most important neurotransmitters. Fat-soluble, it is easily absorbed and crosses the blood-brain barrier resulting in increased dopamine and GABA levels in the brain, and increased production of calming brain alpha- waves. L-theanine has been shown to support improved sleep quality not by sedation but through anxiolysis. Protection Against Glutamate Toxicity There is some evidence L-theanine offers neuroprotective benefits partly due to the antagonistic action of theanine on glutamate subtype aMPA and kainite receptors. By acting on the glutamine (Gln) transporter, it inhibits the incorporation of extracellular Gln into neurons, suppressing the conversion of glutamine to glutamate by glutaminase. This antagonistic activity plays a role in neuroprotection against glutamate toxicity. Optimizes Stress Response In one study where subjects were given L-theanine and a placebo and exposed to stressors to test cortisol levels, the salivary cortisol response was significantly reduced in the subjects taking L-theanine when compared to the placebo. In another study, L-theanine intake resulted in a reduction in heart rate (HR) and salivary immunoglobulin A (s-IgA) responses to acute stress.

ON SALE THIS MONTH - Save $10!!!   NutriClear® Plus is a science-based metabolic cleanse program that supports the body’s detoxification processes. By supplying key nutrients in a delicious-tasting powder, NutriClear® Plus provides the ideal nutritional foundation for those in need of metabolic clearing, while also supporting hepatic function, energy production and intestinal balance. The formula includes easily digested, certified organic pea protein, medium chain triglycerides, added fiber and an extensive array of antioxidants. This powerful combination of micronutrients, NitroGreens®, fiber, fruit and vegetable extracts supports safe and effective detoxification. Each kit is packaged for convenience and contains 30 pouches of NutriClear® Plus powder, 30 NutriClear® Plus supplement packets, which include 5 capsules supplying the active constituents from Bromelain Plus CLA™, Beta-TCP™, Livotrit Plus®, BioProtect™, and MCS-2™, as well as 1 Shaker Cup, and 1 Guidebook. Dosage:  Consume two NutriClear® Plus shakes and supplement packets per day, plus one meal and snacks that work for your schedule.

Equi-Fem™ supplies a comprehensive source of nutrients to support healthy female endocrine function. It includes vitamins, minerals, botanicals, and organ/glandular specific support, with known nutrient synergists. It may be recommended as a general female multi, as well as for those having menopausal and peri-menopausal symptoms, such as hot flashes.

Porphyra-Zyme™ supplies botanical extracts and concentrates, providing naturally occurring chlorophyllin, galactoglycerides, chlorophyll, and other phytonutrients to support the normal, healthy elimination of toxic metals. Unlike traditional chlorophyll products, Porphyra-Zyme™ is a concentrated porphyrin supplement. Porphyrins have the ability to bind divalent metal ions due to the nitrogen atoms of the tetrapyrrole nucleus. The central ion in chlorophyll is magnesium, which is freed from chlorophyll under acidic conditions, permitting other metals to bind in its place. Toxic metals, such as mercury, lead and arsenic, are complexed first. Then excess amounts of other divalent metals, such as calcium, can be complexed by porphyrins. By increasing the porphyrin content, the heavy metal binding capability is also increased, thus providing clinicians with a natural, effective "chelating" tool.

Cytozyme-H™ supplies organ specific support as Neonatal Heart Concentrate (bovine), combined with SOD and catalase important antioxidant enzymes. 

N-Acetyl-L-Cysteine (NAC) 180 Caps Supplies N-acetyl-L-cysteine, a derivative of L-Cysteine. NAC is more stable and better absorbed than L-Cysteine. A potent antioxidant and a precursor to glutathione, NAC is hepatoprotective. NAC supplies N-acetyl-L-cysteine, a derivative of L-Cysteine, which is more stable and better absorbed than L-Cysteine. NAC functions as a potent antioxidant. As the precursor to glutathione intracellular synthesis, it is essential for the synthesis of glutathione. Glutathione is a critical component of the immune system, as it is an important intracellular water-soluble antioxidant. As part of this function, glutathione plays a vital role as the cofactor for the antioxidant enzymes glutathione peroxidase and glutathione transferase. Glutathione is also important to the liver, as the liver utilizes it for drug detoxification. As a metabolite of cysteine, NAC plays an important role in detoxification, and is hepatoprotective. NAC functions in protecting cells against oxidative stress, and contributes to important bodily reactions. As such it is a part of the defensive mechanism toward potential carcinogens, as well as against DNA damage. The role of NAC in acetaminophen toxicity is widely documented, however, NAC contributes to other protective mechanisms as well, including drug conjugation and excretion, peroxide and free radical destruction, maintenance of the redox state of NADPH-NADP, acid-base balance, and the synthesis of sulfated compounds. NAC also plays a role in the development of the central nervous system. There have been numerous studies using NAC, with COPD, particularly amongst patients who smoke. Utilizing NAC in smokers with chronic bronchitis showed a significant reduction in the number of positive bacterial cultures in these patients. 

Monthly SPECIAL - SAVE $5.00 PER BOTTLE De-Stress™ supplies a patented, all natural, bio-active peptide (derived from milk), which has anxiolytic (inhibits anxiety) activity. In other words, De-Stress can be used to reduce stress and anxiety! De-Stress is clinically proven to be effective.  NOTE: All of the above statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Why you may need ADB5-PlusTM: Adrenal fatigue is considered one of the most prevalent debilitating conditions of the past fifty years, affecting millions each year. Despite its commonality, it often goes undiagnosed. The adrenal glands play an essential role in many bodily functions, including stress adaptation and regulation. Specific nutrients, known to provide valuable support for the adrenals, can offer complementary and restorative features to overstressed adrenals. For example, pantothenic acid (vitamin B5) plays an important role in energy production, and a deficiency has been correlated to disruptions in, or abnormal, neurotransmitter production, resulting in difficulty in dealing with stressful situations. Pantothenic acid is essential in the formation of coenzyme A (CoA), as the initial step in the synthesis of CoA is phosphorlyation of pantothenate. CoA is required in the synthesis of the neurotransmitter, acetycholine, a chemical required for nerve transmission. Accordingly, pantothenic acid is sometimes referred to as the “antistress” vitamin. Why we recommend ADB5-PlusTM: ADB5-PlusTM offers a comprehensive choice for adrenal support, incorporating a diverse array of vitamins, minerals, botanicals and glandular components to provide restorative attributes to overstressed adrenals. In addition to pantothenic acid, ADB5-PlusTM provides key components known to support adrenal function, including vitamin C, the B-complex vitamins thiamin, riboflavin, niacin, vitamin B6, vitamin B12 and folic acid, along with NAC, adrenal glandular concentrate, Rhodiola rosea and mushroom derived Tyrosinase. As always, Biotics Research brings you “The Best of Science and Nature”.