Professional Health Products

This may be fulfilled by a product that this manufacturer Private Labels for us When you’re choosing to decrease the levels of histamine in your diet, it’s just that: decreasing. It is simply impossible (and actually unnecessary) to try to eliminate histamines. They’re everywhere. However what you can do, and should focus on, is reducing your intake of high histamine foods along with combining foods that are low in histamine with other foods can help break down and clear histamine from the body. Use this list to help lower your histamine load. Using products like our Histamine Scavenger can greatly reduce one's symptoms of excess histamine. This is one of our BEST selling products with the number of people RE-purchasing at the highest - meaning...it WORKS! On SALE this month - $3.00 off per bottle!!!! Ingredients: Larch Tree Fiber Pine Bark Extract Aloe Vera Leaf Quercetin Bromelain Nettle Leaf Marshmallow Root Bitter Orange Licorice Sugar free, salt free, starch free, preservative free, no artificial colors or flavors or additives, wheat free, soy free, yeast free, no milk derivatives Potential Benefits: Supports normal histamine levels Reduce inflammatory responses to non-allergen exposures Can help the body repair leaky gut, or prevent its onset Supports ABP1 & HNMT gene pathways Description: Histamine is a versatile, yet unique, compound that naturally interacts with several physiological pathways. Typically, bodily injury and antigen exposure promotes the release of histamine. A white blood cell variation known as a basophil and similarly constructed mast cells, found in connective tissue, are the main producers of histamine. Despite various origins and locations, histamine compounds found outside of the CNS contribute to a universal goal: initiating an inflammatory response. Histamine, as a result of corresponding neural receptors, has the potential for profound effects on the hypothalamus and other neurotransmitters: specifically effecting appetite and sleep patterns. Therefore, increased histamine can disrupt usual compound levels in the CNS.  Secreted histamine also promotes vasodilation, blood plasma release from adjacent blood vessels, and stimulates gastric acid production. Vasodilation allows for greater capillary permeability; therefore, white blood cells are capable of contacting pathogens found in interstitial fluid, also potentially effecting intestinal permeability.  Excessive histamine can be correlated to genetic mutations, leaky gut, allergies, and an individual’s diet. Studies have suggested gliadin, a protein found in wheat, to be involved with mast cell function and secretion of histamine; similarly, gliadin also stimulates the release of Zonulin. Under further observation, Zonulin has been found, during an ex vivo study, to increase intestinal permeability, serving as another contributor to a leaky gut.  Genetic mutations found in the ABP1 and HNMT genes are potential indicators for elevated histamine. Furthermore, increased histamine levels can result in heart palpitations, low blood pressure, hypertension, fatigue, anxiety, joint pain, irritable bowel syndrome, stomach ulcers, adrenal gland fatigue, and altered sleep patterns. Histamine Scavenger contains the essential ingredients believed to promote the reduction of harmful histamine accumulation.   Genetic supplementation is complex and requires a deep understanding of the entire genetic picture.  Our Genetics Membership includes the kit, a full workup, review, report, summary, Dr. Conners’ personalized recommendations - and MORE.  Click HERE for details. Histamine Scavenger is designed to reduce histamine (an inflammatory chemical) in the tissues. Clear Histamine Scavenger

This may be fulfilled by a product that this manufacturer Private Labels for us NOTE: PON1 and Phase 2 are the same product Ingredients Quercitin Pomegranite Astaxanthin Soy free, yeast free, dairy free, sugar free, gluten free, no artificial colors or flavors, preservative free. Potential Benefits Supports PON1 gene pathways Assists the liver in its ability to remove toxins from the body Description Phase 2 - PON1 Assist is a combo product created to help support people with defects in the PON1 detoxification genes. These genes are responsible for assisting your body to get rid of large chemicals such as pesticides, insecticides, vaccinations, some medications, as well as free radicals. Mutations of the PON1 gene inhibit enzyme efficiency and are believed to create an increased risk for athero- sclerosis and other coronary implications. Paraoxonase 1, also known as PON1, is a critical enzyme located on high density lipoproteins and is responsible for hydrolyzing organo-phosphates and insecticides; therefore, the PON1 enzyme directly regulates the ability to secrete these chemicals following an environmental exposure. Organophosphates, the active ingredient found in herbicides, is known to disrupt the digestive tract and act as a neurotoxin. Symptoms of toxic levels of organophosphates include, but are not limited to, headaches, diarrhea, restlessness, convulsions, labored breathing, weakness, frequent urination, and nausea. Due to its location, the PON1 enzyme protects HDL’s against peroxidation that is implemented through contact with low density lipoproteins The ability to support the PON1 enzyme, through the supplementation of natural cofactors, has been revolutionized with PON1 Assist. Individuals with the PON1 variant should be advised to supplement with PON1 Assist for long term health support. Also consider using “Addex” Homeopathic formula if there has been exposure to insecticides and pesticides.   Genetic supplementation is complex and requires a deep understanding of the entire genetic picture.  Our Genetics Membership includes the kit, a full workup, review, report, summary, Dr. Conners’ personalized recommendations - and MORE.  Click HERE for details.   Free Download - The 7 Phases of Detox Videos

Ingredients: Danshen Root Magnolia Bark Extract L-Theanine Calcium Pyruvate Citicoline Sugar free, preservative free, no artificial colors or flavors or additives, wheat free, soy free, yeast free, no milk derivatives Potential Benefits: supports the conversion of glutamate to GABA (for under methylators) helps reduce excess glutamates in the body can have a calming/anxiety reducing effect Description: Glutamate Scavenger II has been carefully formulated to support the body’s natural ability to balance glutamate and GABA, supporting relaxation, restful sleep, and decreasing inflammation. L-Theanine provides gentle methylation support for under-methylators.  This product is designed to help the body reduce glutamate levels. Glutamate is an excitatory neurotransmitter that, in excess, can lead to an array of symptoms and health problems. Defects in specific genes may lead to higher glutamate levels. Glutamate, an excitatory neurotransmitter, is a cofactor for the inhibitory molecule GABA and must be strictly moderated for optimal function of the central nervous system. Mutations found in the GAD gene, responsible for producing GABA, may signify a relationship to gluta- mate levels. Excessive levels of glutamate, known as excitotoxicity, can result in cellular damage, anxiety and even cell death.  Moreover, excessive glutamate has the potential to increase acetyl-choline, induce insomnia, and reduce levels of glutathione, a critical antioxidant. Glutamate Scavenger II has the critical ingredients to naturally support the body’s ability to balance neurotransmitters levels; it is important to note that this is the second Glutamate Scavenger formula, without niacin, which may be especially beneficial for those with low total methyl group production. Read our article: Avoid Glucose, Glutamine Foods with Cancer, Stop Feeding It!    Genetic supplementation is complex and requires a deep understanding of the entire genetic picture.  Our Genetics Membership includes the kit, a full workup, review, report, summary, Dr. Conners’ personalized recommendations - and MORE.  Click HERE for details.    

This formula has 200mg of Catalase and 200mg of SOD per cap Ingredients: Catalase Superoxide Dismutase Soy free, yeast free, starch free, salt free, dairy free, sugar free, no milk derivatives, no artificial colors or flavors or additives, preservative free Potential Benefits: neutralizes superoxide free-radicals reduces peroxynitrited Description: If someone has the SOD variant, that reduces super oxide dismutase (that neutralizes super oxide) or other variants that increase peroxynitrite, using nutrition to further support S.O.D and scavenge peroxynitrite may be quite beneficial. This product contains equal amounts of SOD and catalase to neutralize the superoxide free-radical, thereby reducing peroxynitrite. *Packed in DR CapsTM, (Delayed Release Capsules), which are acid resistant and release in a neutral pH environment   Genetic supplementation is complex and requires a deep understanding of the entire genetic picture.  Our Genetics Membership includes the kit, a full workup, review, report, summary, Dr. Conners’ personalized recommendations - and MORE.  Click HERE for details.  

This is a WHOLE-FOOD B supplement! Ingredients: Thiamin - B1 Riboflavin - B2 Niacin - B3 Pyradoxine - B6 Folate - B9 Pantothenic Acid - B5 Soy free, yeast free, sugar free, gluten free, no artificial colors or flavors, preservative free Potential Benefits: Naturally sourced support for B Vitamin deficiency Description: The B vitamin Complex catalyzes various chain reactions by acting as co enzymes for the release of energy. For example, niacin (vitamin B3) plays a key role in fifty metabolic reactions in glycolysis for the release of energy via the Krebs Cycle and the monophosphate shunt. Niacin is also involved with the de animation of amino acids, fatty acid oxidation, and steroid production. Clinical trials have demonstrated the efficacy of vitamin B therapy in stress management. Pantothenic acid (vitamin B5) deficient rats have been shown to have low adrenal function and poor motor control. Rats fed a diet low in pantothenic acid produced lowered catechol-amines and corticoid steroids. This work suggests the importance of pantothenic acid in the support of the adrenal gland. Riboflavin (vitamin B2) function as a hydrogen transfer agent and as a coenzyme in a variety of energy reactions within the body. Riboflavin is also involved in the release of corticotrophin hormone from the pituitary gland. Folic acid is a co-factor for the synthesis of methionine and nucleic acids in the body. Clinical deficiency symptoms include miscarriages, anemia, gastrointestinal problems, tremors, and muscular atrophy. B-Specific Naturally formulation contains a unique and complete blend of Orgen-B’s water-soluble B vitamins: thiamin, riboflavin, naicin, pyridoxine, folate, and pantothenic acid. These vitamins are not synthesized by the body and must be supplied by the diet or produced by the microbiome. The B Complex is required for the metabolism of proteins, fats, and carbohydrates. This complex also catalyzes enzymatic chain reactions by acting as coenzymes for the release of energy and has been demonstrated in clinical trials to help aid in stress management. This formulation also contains Orgen-B’s proprietary organic blend, humic acid, guava, holy basil, and lemon extract. Bottle Count: 60 delayed release capsules Genetic supplementation is complex and requires a deep understanding of the entire genetic picture.  Our Genetics Membership includes the kit, a full workup, review, report, summary, Dr. Conners’ personalized recommendations - and MORE.  Click HERE for details.

Ingredients: Vitamin B12 Soy free, yeast free, gluten free, no artificial colors or flavors or additives, preservative free Potential Benefits: promotes healthy cellular detoxification supports DNA synthesis Description: Pro Hydroxy-Cobalamin is a non-methylated form of Vitamin B-12.If the individual has COMT or MAO variants expressed, or may need less methyl groups for other reasons, Pro Hydroxocobalamin is usually a better form of Vitamin B-12. Pro Hydroxocobalamin provides 1,200 mcg of hydroxocobalamin in an easy-to-deliver lozenge form. This form of vitamin B12 easily converts to methylcobalamin (a coenzyme form of B12 utilized within the body) and is well tolerated for those who have difficulty taking “pre-methylated” B vitamins. Vitamin B12 is required for proper red blood cell formation, neurological function, healthy cellular detoxification, and DNA synthesis. Vitamin B12 functions as a cofactor for methionine synthase and L-methylmalonyl-CoA mutase. Unlike cyanocobalamin, which consists of cobalamin attached to a cyanide molecule, this product contains hydroxocobalamin which does not contain any potentially harmful compounds that require additional processing for safe removal from the body.   Genetic supplementation is complex and requires a deep understanding of the entire genetic picture.  Our Genetics Membership includes the kit, a full workup, review, report, summary, Dr. Conners’ personalized recommendations - and MORE.  Click HERE for details.  

Ingredients: Vitamin B6 Calcium Larch Tree Fiber L-Orthinine L-Citruline Yucca Root Alpha-Ketoglutarate L-Lysine Sugar free, salt free, preservative free, no artificial colors or flavors, wheat free, soy free, yeast free, no milk derivatives, gluten free **Does contain RICE Potential Benefits: Provides a unique blend of ingredients that support the Urea Cycle Help reduce excess ammonia levels in the blood Supports digestion in an effort to create less ammonia Ammonia Scavenger Created when amino groups are removed from amino acids, high nitrogen levels pose toxic traits; therefore, nitrogen is reduced through ammonia synthesis due to its properties as a cofactor. Production of ammonia, NH3, is also seen through the gluconeogenesic transition of amino acids to glucose and in the GI tract during protein digestion. Ammonia, toxic to the central nervous system, is predominately eliminated through the Urea Cycle. Researchers believe genetic mutations found in the CBS, BHMT, MTHFR, MTR/MTRR, PEMT/BHMT, SUOX and NOS genes are thought to increase NH3 levels and reduce Urea Cycle function.2 The responsibility to neutralize excessive ammonia, due to an inhibited Urea Cycle, is met by the utilization of BH4. The reduction of available BH4 leads to a potential reduction of neurotransmitters and inflammation from NOS uncoupling, thus impacting an individual physically and emotionally. Elevated glutamate, an excitatory neurotransmitter produced by alpha-ketoglutarate and NH3, has the potential to act as an excitotoxin that can cause neural damage and cell death. Abnormal ammonia levels can additionally cause, yet is not limited to, tremors, fatigue, enlarged liver, headaches, irritability, seizures and a lack of concentration.11 Ammonia Scavenger provides comprehensive nutritional support to the Urea Cycle, agents to absorb ammonia and the ability to support digestion in effort to create less ammonia. Bottle Count: 90 delayed release capsules Genetic supplementation is complex and requires a deep understanding of the entire genetic picture.  Our Genetics Membership includes the kit, a full workup, review, report, summary, Dr. Conners’ personalized recommendations - and MORE.  Click HERE for details.

Fatty Acid Assist contains many nutrients and herbals that support the healthy transport of fats into the cell for production of Acetyl- CoA and the to ATP. Ingredients: Vitamin B2 - Riboflavin N-Acetyl-L-Carnitine L-Lysine Fennel seed Choline Bitartrate Pantethine Soy free, yeast free, sugar free, dairy free, gluten free, no artificial colors or flavors, preservative free Potential Benefits: supports the body for proper beta-oxidation supports the digestion, utilization and transportation of fats into the cell Description: Our bodies rely on the proper metabolism of nutrients for energy and optimal function of all aspects of life. One of the most crucial metabolic pathways, known as beta-oxidation, the oxidation of fats, is regulated by a multifactorial cascade of events and dependent upon several key components. Beta-Oxidation utilizes ketone bodies, produced from fats in the liver, to create acetyl-CoA for the Citric Acid Cycle. Initial introduction of ketones to the inner matrix of the mitochondria is critical for overall homeostasis. Several implications can affect the transportation and mitochondrial transmembrane transfer of fats and their byproducts. This results in insufficient utilization of fats and can negatively influence health. Inhibiting aspects can include genetic predispositions such as, mutations effecting carnitine and acetyl-CoA acetyltransferase production. Suberate and ethylmalonate build up is a key indicator that fats are not being properly metabolized inside the mitochondria. Influences of fatty acid oxidation disorder can be observed through fatigue, inflammation and increased cholesterol. Inflammation, as a result of fat accumulation, is known to lead to toxin deposits in the circulatory system, portal hypertension, and water retention. Despite being stored in organs and arteries, fats are also known to be deposited throughout the body as well; Fatty Acid Assist contains the essential nutrients to naturally support the body for proper beta-oxidation. Genetic supplementation is complex and requires a deep understanding of the entire genetic picture.  Our Genetics Membership includes the kit, a full workup, review, report, summary, Dr. Conners’ personalized recommendations - and MORE.  Click HERE for details.  

Ingredients: Folinic acid Royal Jelly Powder SAMe active ion Lithium orotate Sugar free, salt free, starch free, preservative free, no artificial colors or flavors or additives, wheat free, soy free, yeast free, no milk derivatives Potential Benefits: supports body's natural ability to stimulate neurotransmitter production supports body's natural ability to stimulate Nitric Oxide production Description: BH4-Assist helps to maintain proper levels of tetrahydrobiopterin (BH4). BH4 plays a critical role in both neurotransmitter and nitric oxide production. It can be depleted by genetic polymorphisms in MTHFR A1298C, DHFR, high levels of ammonia (from CBS mutations), oxidative stress, or lack of SAMe or NADH. This formulation contains Royal Jelly, which has naturally occurring BH4, folinic acid, 6S-5-MTHF, SAMe and lithium to support production of BH4. Bottle Count: 60 capsules Genetic supplementation is complex and requires a deep understanding of the entire genetic picture.  Our Genetics Membership includes the kit, a full workup, review, report, summary, Dr. Conners’ personalized recommendations - and MORE.  Click HERE for details.

Ingredients Activated Broccoli Raffinate seed Sulforaphane Glucosinolate Myrosinase Enzyme Tumeric Pomegranate Extract Pterocarpus Marsupium pulp Ginkgo Biloba Extract leaf Dong Quai root Trans-Resveratrol root Grapeseed Extract Potential Benefits provides support for the Nrf2 process in cells that create antioxidants & Phase II enzyme Supports cellular integrity and stabilizes proteins Description Your Nrf2 pathway is your primary intracellular path to detoxify oxidizing agents. Failure for Nrf2 to be released to do its job (common with Keap1 gene defects) and Nrf2 production (NFE2 gene defects) may decrease Nrf2 function and be a cause of severe illness. Nrf2 Basics Nrf2, or nuclear factor erythroid-2-related factor 2, is a master transcription factor for hundreds of human genes involved in cell protection and detoxification. Nrf2 protects cells against oxidative stress and environmental toxins through the induction of cytoprotective genes.[1] Cells devote great energy to maintaining the Nrf2 pathway, ensuring its rapid induction upon cellular insult, with return to normal levels once the threat has been neutralized. Key Nrf2 Actions Nrf2 has four key domains:1. Nrf2 quells oxidative stress by stimulating key antioxidant enzymes such as heme oxygenase and glutathionerelated enzymes. 2. Nrf2 damps inflammation by down-regulating pro-inflammatory cytokines such as interleukins and NFkappaB, and by up-regulating antioxidant responses.[1,3] 3. Nrf2 promotes mitochondrial biogenesis and improves mitochondrial function,[1] with all that that implies. 4. Nrf2 stimulates autophagy, which removes damaged and toxic molecules and aggregates [1,4] (see tech info sheet: Autophagy Assist). Inducing Nrf2 The Nrf2 pathway can be induced by a wide variety of dietary and plant chemicals, by low-level oxidative stress (hormesis effect), and by exercise and caloric restriction. Healthy diets such as the Mediterranean and Okinawan diets, "paleo" diets emphasizing a variety of vegetables, and WFPB (whole food plant-based) diets, are rich in compounds that boost Nrf2. The Standard American Diet (SAD), loaded with refined sugars and fats, is sadly lacking in same. Nrf2 appears to be the final common pathway for the protective effects of a plethora of the best-documented phytochemicals including phenolic antioxidants (grapes, grape seed, pomegranate, green tea), sulforaphane (broccoli and other crucifers), carotenoids (red, green and yellow vegetables), and omega-3 fatty acids. Free Download - The 7 Phases of Detox Genetic supplementation is complex and requires a deep understanding of the entire genetic picture.  Our Genetics Membership includes the kit, a full workup, review, report, summary, Dr. Conners’ personalized recommendations - and MORE.  Click HERE for details.  

ABP1 Assist is formulated with DAO and other enzymes to help those with ABP1 gene defects, and hence the inability to make DAO enzyme essential to digest histamines in the GUT Ingredients: Vitamin B6 Copper Diamine Oxidase Lyophilized Ovine Thymus Tissue Apple Polyphenols Rutin Soy free, yeast free, dairy free, sugar free, gluten free, no artificial colors or flavors, preservative free Potential Benefits: supports overall function of ABP1 gene reduce reactions to histamine (and high histamine foods) supports natural ability to break down histamine in the body reduce sensitivity to NSAIDs reduce occurrence/severity of migraines supports mental stability can lessen symptoms of ulcerative colitis 2 capsules contain enough DAO to degrade 75,000 uM/hour of Histidine** Description - ABP1 Assist Many individuals have health concerns due to the inability to digest foods high in histamine. The amine oxidase copper containing 1 gene, known as ABP1 or AOC1, is responsible for the production of the diamine oxidase enzyme and is expressed in the colon, kidney, thymus and seminal vesicles. The diamine oxidase, DAO, enzyme is primarily involved in the degradation of extracellular histamine, D-serine, and other inflammatory stimulating compounds. Several single nucleotide polymorphisms of the ABP1 gene have been reported to be major determinates in the function and serum activity of the DAO enzyme; moreover, Music et al. (2011) reported that serum DAO enzyme activity is a useful indicator of histamine intolerance. Abnormal function of the DAO enzyme has been associated with NSAID sensitivity, migraines, schizophrenia, histamine intolerance, and as a factor in the severity of ulcerative colitis. ABP1 Assist provides innovative and groundbreaking dietary assistance designed to support the natural ability to break down histamine and produce the DAO enzyme. Bottle Count: 90 delayed release capsules Genetic supplementation is complex and requires a deep understanding of the entire genetic picture.  Our Genetics Membership includes the kit, a full workup, review, report, summary, Dr. Conners’ personalized recommendations - and MORE.  Click HERE for details.

Ingredients: Vitamin D Vitamin K2 Vitamin B6 Calcium citrate Magnesium orotate Lactospore Potential Benefits: aids in the removal of Oxalic acid supports a healthy gastrointestinal microbiome Description: Oxalate Scavenger contains Calcium Citrate and Magnesium Orotate to bind with dietary oxalic acid so that it can be safely excreted from the body. Vitamin B6 helps support healthy metabolism of glyoxalate to glycine rather than oxalate. It also includes the probiotic LactoSpore to support a healthy gastrointestinal microbiome. Oxalates are compounds that naturally exist in many generally healthy foods and can come from overgrowth of yeast or fungus as well as exposure to mold. They bind to metal ions and form precipitates, which can cause various health problems depending on where the precipitate is deposited. Individuals with elevated oxalate levels may experience pain as the result of oxalate crystals precipitating with minerals in tissue. Those with AGXT, HOGA1, GRHPR, or SPP1 genetic variants have been found to have a higher amounts of oxalates. Consider Oxalate Balancer as well if you need antimicrobial support. Oxalate Scavenger is intended for those with genetic defects that may warrant supporting this pathway. See video:   Genetic supplementation is complex and requires a deep understanding of the entire genetic picture.  Our Genetics Membership includes the kit, a full workup, review, report, summary, Dr. Conners’ personalized recommendations - and MORE.  Click HERE for details.  

This may be fulfilled by a product that this manufacturer Private Labels for us Eco Thyroid 37 and Clear Thyroid Support are the SAME products Ingredients: Thyroid tissue Sugar free, starch free, salt free, preservative free, no artificial flavors or colors or additives, wheat free, yeast free, no milk derivatives, gluten free Potential Benefits: Provides natural thyroid support Supports overall hormonal balance & health Description: Eco Thyroid 37 / Clear Thyroid Support are a powerful product that provides natural thyroid support. It contains thyroid tissue concentrate derived from pure, lyophilized tissue concentrates from New Zealand, which is considered the cleanest and most environmentally responsible country to source from on the planet. It also contains a rich amount of naturally occurring hormone precursors that support thyroid gland function and overall health. Bottle Count: 120 Veggie Capsules

This product may be termed as one of them multiples for your genes as it helps support several pathways. Ingredients: Zinc Copper Manganese Selenomethionine Apple Polyphenols Bee Pollen Kale Liver Organic Turkey Tail Mushrooms Catalase Superoxide Dismutase Marine Phytoplankton Potential Benefits: provides food-based ingredients for complete vitamin, mineral, amino acid, and antioxidants provides SOD and Catalase Supports SOD production Description Oxidative Stress and Antioxidants Normal metabolism, and exposure to toxins and stress, leaves a residue of free radicals – reactive atoms with one or more unpaired electrons. The reactive nature of free radicals gives rise to potentially harmful interactions with sensitive cellular proteins, lipids and DNA. These interactions, called oxidative stress, occur when free radicals overwhelm the antioxidant defenses, causing an imbalance favoring oxidants. The result is disruption of a delicate cellular redox signaling matrix, and molecular damage known to underly many diseases. Normally, oxidative stress is controlled by small-molecule, low-molecular-weight, nonenzyme antioxidants such as vitamins A, C and E, carotenoids, polyphenols, and glutathione, and especially by antioxidant enzymes such as superoxide dismutase, catalase and glutathione peroxidase. Free Radical Theory For many years, free radicals and oxidative stress were held to be a prime cause of chronic disease and premature aging. This was known, and widely embraced, as the free radical theory of aging. It was thought that liberal supplementation with antioxidant compounds would quench the reactive free radicals, mitigate oxidative stress, and prevent many diseases, perhaps even slow the aging process. Research in recent years, including the failure of several high-profile antioxidant supplement trials, has forced a revision of the theory. Although the reaction has been excessive and unfair, legitimate questions have been raised regarding the wisdom of supplementing with high doses of isolated antioxidant compounds. Free radicals have beneficial as well as harmful roles, and not all oxidation caused by free radicals leads to harmful oxidative stress. Although the evidence is overwhelming that uncontrolled oxidative stress is pathogenic, and that consumption of diets rich in antioxidant nutrients and phytochemicals is beneficial, there also exists oxidative "stress" that is physiologic and desirable. Mitochondrial oxidations, for example, are vital for energy production and all cellular functions, and oxidations in white blood cells are vital for destruction of invasive microbes. The situation was summed eloquently by Levonen and colleagues: "the idea that free radicals are bad and antioxidants are good' is clearly undergoing a critical and high-profile reappraisal.... the oxidative stress hypothesis has reached the limits of its utility and should be replaced with the 'redox biology paradigm' in which antioxidants play the primary role of modulating the complex networks controlling cell signaling and metabolism." In this view, antioxidants serve as regulators of cellular redox networks – the complex of signaling pathways that control cell function, including free radicals in their beneficial roles – rather than exclusively protecting against the free radical "bad actors". Embracing the New Paradigm In adopting this new paradigm, it is important still to retain the lessons of the preceeding several decades of research, which showed beyond question that uncontrolled oxidative stress damages fragile lipid and other molecules, promotes inflammation, is generally pathogenic, and speeds the aging process. There remains a massive literature linking oxidative stress with most degenerative diseases including cancer, atherosclerosis, cognitive impairment and Alzheimer's disease, cataracts, macular degeneration and many others. Whole books are still written on this subject. The old paradigm had value, but led to foolishly-designed trials using very high doses of isolated small-molecule antioxidants, with the expectation that this would cure or mitigate major diseases. These expectations were unwise. Although such supplementation might have been effective in Controlling inappropriate oxidative stress, it may also have depressed essential oxidations such as those required for synthesis of prostaglandins or for mitochondrial energy production. Whatever the mechanism, the bottom line was that too much of a good thing led to typically null results, and in a very few cases bad results. The new paradigm modifies but does not overthrow the old. There is room for both, and the new paradigm encourages not abandonment of antioxidants, but more mature and wise use of them: in combination, in lower doses, and with an emphasis on activating defensive enzymes rather than direct scavenging of free radicals.   Genetic supplementation is complex and requires a deep understanding of the entire genetic picture.  Our Genetics Membership includes the kit, a full workup, review, report, summary, Dr. Conners’ personalized recommendations - and MORE.  Click HERE for details.  

Ingredients: N-Acetyl L-Carnitine Yucca powder Lecithin (from sunflower) TMG - Trimethylglycine Sugar free, salt free, starch free, preservative free, no artificial colors or flavors or additives, wheat free, soy free, yeast free, no milk derivatives Potential Benefits: Supports the BHMT gene pathway may minimize the effects of up-regulated CBS provides cardiovascular support Description: CBS/BHMT Assist supports the Transsulphuration pathway as well as the Methionine pathway. CBS/BHMT Assist is a formulation that contains nutrients that help support the enzymes Cystathionine-β-synthase and Betaine-homocysteine S-methyltransferase. CBS catalyzes the first step of the transsulfuration pathway, converting homocysteine into cystathionine. Elevated homocysteine levels are associated with a myriad of chronic health conditions including cardiovascular disease. The BHMT enzyme catalyzes a methyl transfer from betaine to homocysteine to form dimethylglycine and methionine, respectively. Methionine is needed to produce our body’s primary methyl donor, SAMe. Genetic polymorphisms and epigenetic factors can cause these enzymes to function improperly, leading to high homocysteine and low SAMe. The nutrients contained in this product such as N-Acetyl L-Carnitine, Yucca, Lecithin and Trimethylglycine can help support these very important biological reactions. Bottle Count: 60 capsules Genetic supplementation is complex and requires a deep understanding of the entire genetic picture.  Our Genetics Membership includes the kit, a full workup, review, report, summary, Dr. Conners’ personalized recommendations - and MORE.  Click HERE for details.