Women's Health

For the temporary relief of congestion, coughing, sore throat, hoarseness, sneezing, acute fever, or minor body aches or pains. Serving Size: 10 DropsActive Ingredients:Eucalyptus globulus 2XEucalyptus globulus 10XEucalyptus globulus 30XAconitum napellus 3XAconitum napellus 10XAconitum napellus 30XAconitum napellus 200XIpecacuanha 3XIpecacuanha 10XIpecacuanha 30XBase Ingredients: 40% ethanol, purified water. *This item may take longer to ship out*

For the temporary relief of minor acne-like conditions, blackheads, or pimples. Serving Size: 10 DropsActive Ingredients:Arctium lappa 3XBerberis aquifolium 3XHydrocotyle asiatica 3XLedum palustre 4XNux vomica 6XSanguinaria canadensis 6XSilicea 6XSulphur 6XAntimonium crudum 8XCarbo animalis 12XKali bromatum 12XNatrum muriaticum 12XBase Ingredients: 20% ethanol, purified water. *This item may take longer to ship out*

Synergistic herbs for support during acute upper respiratory illnesses such as sinusitis and laryngitis. Serving Size: One Teaspoon (4.9 mL)Active Ingredients:Echinacea angustifolia Aerial Parts & Root Extract (1:1) 0.89mLEuropean Elder (Sambucus nigra) Berry Extract (1:1) 0.89mLLinden (Tilia x europaea) Flower Extract (1:1) 0.89mLYarrow (Achillea millefolium) Flower Extract (1:1) 0.89mLLicorice (Glycyrrhiza glabra) Root Extract (1:1) 0.72mLGinger (Zingiber officinale) Root Extract (1:1) 0.43mLAnise (Pimpinella anisum) Seed Extract (1:1) 0.18mLOther Ingredients: Grain alcohol (40-45%) and purified water. Serving Size: One Teaspoon (4.9 mL) *This item may take longer to ship out*

For the temporary relief of general fatigue, sneezing, occasional headache, or difficulty breathing due to sensitivity to phenolic compounds found in foods or other products. Serving Size: 10 DropsActive Ingredients:Acetaldehyde 9XAcetaldehyde 12XAcetaldehyde 30XAcetaldehyde 60XBase Ingredients: 20% ethanol, purified water. *This item may take longer to ship out*

For the temporary relief of mild abdominal pain, cramping, or spasms, bloating, or flatulence.  Serving Size: 10 DropsActive Ingredients:Chamomilla 3XLycopodium clavatum 5XCarbo vegetabilis 6XNatrum sulphuricum 6XSolar plexus 6XStomach 6XVagus nerve 6XMuriaticum acidum 12XNux vomica 30XBase Ingredients: 20% ethanol, purified water. *This item may take longer to ship out*

For the temporary relief of tiredness, dizziness or lightheadedness, nausea or vomiting, gas or bloating, runny or stuffy nose, itching or flushing, or occasional headache due to sensitivity to or exposure to alpha/beta antagonist or calcium channel blocking agents. Serving Size: 10 DropsActive Ingredients:Colchicum autumnale 3XBrain 6XHeart 6XKidney 6XLung 6XNaja tripudians 8XLedum palustre 9XCactus grandiflorus 3CArgentum nitricum 6CSecale cornutum 6CMixed isode 30CMixed isode 60CMixed isode 100CBase Ingredients: 20% ethanol, purified water. *This item may take longer to ship out*

For the temporary relief of difficulty losing weight or reducing body fat, general weakness, or muscle fatigue.  Serving Size: 10 DropsActive Ingredients:Arginine 3XArginine 12XArginine 30XL-carnitine 3XL-carnitine 12XL-carnitine 30XOrnithine 3XOrnithine 12XOrnithine 30XGlucosamine sulfate 6XVanadium metallicum 6XVanadium metallicum 12XBase Ingredients: 20% ethanol, purified water. *This item may take longer to ship out*

Product Highlights, Clinical Applications Supports Healthy Testosterone Levels Supports Healthy Libido and Performance Supports Overall Vitality Optimizes Physical Strength and Endurance Supports Cognition Stamina is a powerful supplement designed to enhance vitality, performance, and overall well-being in both men and women. This formula features two clinically-tested, standardized, and patented ingredients: PrimaVie® Shilajit and LJ100® Eurycoma longifolia. These potent components are known to support healthy androgen biosynthesis and modulate sex hormone-binding globulin, ensuring optimal levels of bioavailable testosterone. Key Ingredients PrimaVie® Shilajit (500 mg): Rich in Dibenzo-α pyrones (DBPs) & Dibenzo-α pyrone Chromoproteins (DCPs), this mineral-rich phytocomplex is renowned for its rejuvenating qualities, supporting physical performance and reducing fatigue. Shilajit has been used in Ayurvedic medicine for centuries, promoting strength, recovery, and cognitive function. LJ100® Eurycoma longifolia Extract (200 mg): Also known as Malaysian ginseng, this root extract supports healthy testosterone levels, libido, energy, and sports performance. LJ100® is backed by multiple clinical studies demonstrating its efficacy in improving sexual desire, performance, and overall vitality. Benefits Boosts Testosterone Levels: Supports healthy testosterone production, enhancing libido and performance in both men and women. Enhances Physical and Mental Performance: Optimizes strength, endurance, and cognitive function, reducing fatigue and promoting overall vitality. Clinically-Tested Ingredients: Features PrimaVie® Shilajit and LJ100® Eurycoma longifolia, both of which have been proven safe and effective in numerous studies. Usage Take two capsules in the morning, or as directed by your healthcare professional. Other Ingredients Capsule (hypromellose and water) Microcrystalline cellulose Dicalcium phosphate dihydrate Ascorbyl palmitate Silica Why Choose Stamina? Stamina is specifically formulated for those seeking to enhance their vitality, strength, and overall well-being. Whether you're looking to improve your physical performance, boost your libido, or support cognitive function, Stamina provides a safe and effective solution. Clinical Backing Numerous studies have demonstrated the efficacy and safety of both PrimaVie® Shilajit and LJ100® Eurycoma longifolia. From boosting testosterone levels to supporting cognitive function, these ingredients offer a comprehensive approach to enhancing your health and performance. Conclusion Elevate your vitality and performance with Stamina. Harness the power of clinically-tested ingredients to support your overall health and well-being. Order now and experience the benefits of a healthier, more vibrant you! Discussion Five percent of males aged 40-50 years and as many as 70% of males over 70 years are confronted with “hypogonadism.” Low testosterone levels have been associated with a decline in libido, erectile dysfunction, lack of energy, less physical strength and endurance, loss of height, decreased enjoyment in life, low mood, feeling grumpy, falling asleep after dinner, and decreased work performance.[1,2] Some studies suggest that low testosterone may also contribute to cognitive decline.[3,4] Although sometimes thought of as a male hormone, a review study of the clinicalsignificance of testosterone has shown its positive association with sexual function and a healthy libido in women.[5] Most circulating testosterone is bound to sex hormone-binding globulin (SHBG). Only the lesser amount of testosterone not bound to SHBG is considered bioavailable.[6] Stamina features a blend of ingredients designed to support healthy androgen biosynthesis, which includes modulating the influence of SHBG. Shilajit is a naturally occurring, mineral-rich phytocomplex with many bioactive components, including fulvic acids. It comprises rock humus, rock minerals, and organic substances that have been compressed by layers of rock mixed with marine organisms and microbial metabolites.[7] Shilajit has a rich history of use in Indian ayurvedic and siddha medicine as a health and wellness optimizer. It is known as a rasayana because of its rejuvenating qualities, which include heightening physical performance and relieving fatigue.[8] According to an article in the American Journal of Clinical Nutrition, weightlifters use shilajit to promote better strength, recovery, and muscular hypertrophy and also to combat physical stress, but human data on these uses are lacking.[9] Animal and human studies have documented the safety of shilajit. The oral median lethal dose (LD50) is > 200 grams, and chronic use at doses of 0.2–1.0 g/kg body weight appear to be safe.[7] Upwards of 50 studies on shilajit suggest that it has a positive effect on testosteronelevels and adaptogenic, antioxidant, cytokine-balancing, immunomodulatory, and antidyslipidemic activities.[10] Fulvic acid, the main bioactive component in shilajit, blocks tau proteins self-aggregation suggesting it may have a role in supporting cognition.[11] PrimaVie® shilajit at a dose of 250 mg/capsule consumed twice daily after major meals for 90 days was evaluated in 75 healthy male volunteers aged 45-55 for its testosterone secretion efficacy and its stimulation effects. This double-blind placebo-controlled study revealed that PrimaVie shilajit, when compared to placebo, significantly (P < 0.05) increased total testosterone, free testosterone, and dehydroepiandrosterone (DHEA). The levels of testosterone synthesis-supportive gonadotropic hormones were well-maintained.[7] Another study further demonstrated the safety and also the spermatogenic nature of shilajit. Infertile males (n = 35) took 100 mg of PrimaVie shilajit twice daily after major meals for 90 days. At completion, 28 of the subjects had significant (P < 0.001) improvement compared to baseline values of factors related to fertility. Furthermore, atthe study’s completion, the semen’s content of malondialdehyde (MDA), a marker foroxidative stress, was reduced. High-performance liquid chromatography (HPLC) revealed that the semen had constituents of PrimaVie shilajit. Compared to baseline, serum levels of testosterone rose 23.5% (P < 0.001) and follicle-stimulating hormone (FSH) rose 9.4% (P < 0.05). Liver and kidney profiles were unchanged.[12] In addition, the safe use of PrimaVie shilajit in either gender was demonstrated in anexperimental study on skeletal muscle adaptation in human subjects (n = 16), ages 21-70 years. Participants were given 250 mg of PrimaVie with no adverse effects during the 12-week study period.[13] Eurycoma longifolia root (Malaysian ginseng) is considered a tonic and an adaptogen for supporting healthy libido, energy, sports performance, and weight management by promoting healthy testosterone levels and freeing testosterone from SHBG. Eurypeptides activate the CYP-17 enzyme, which plays a key role in production of DHEA, progesterone, testosterone, and pheromone via the metabolism of regnenolone. A systemic review and meta-analysis of randomized controlled studies (n = 139) concluded that the herbal extract “may have clinical effect on erectile function. However, more efficacy trials are warranted to further support current evidence.”[14] LJ100® Eurycoma longifolia is a root extract whose safety and efficacy is backed by animal and at least 12 human clinical studies. Compound isolation, a patented waterextraction process, and technologically advanced manufacturing methods ensure the purity of this ingredient and allow for the capture of the potent, biologically active eurypeptides. A randomized, placebo-controlled, two-month study (n = 20) focused on the outcomes of LJ100 on various parameters in male volunteers aged 38-58 who had varied health conditions and consumed either a placebo or 200, 400, or 600 mg of LJ100. The herb-consuming volunteers showed improvement in sexual desire and performance. Also, testosterone and DHEA levels were high-normal when compared to baseline; HDL cholesterol improved; those who had type-2 diabetes showed improvement in blood glucose levels; and insulin-like growth factors (IGF-1) were high-normal (lower levels of IGF-1 are correlated with higher body fat). Compared to those on placebo, the majority of the volunteers on LJ100 had high-normal levels of thyroxine suggesting higher metabolism. Blood and lipid panels and liver and renal function profiles, electrolytes, and various tumor markers including prostate-specific antigen (PSA) were within normal range.[15] The benefits of LJ100 are not limited to males or particular age groups. Two studies, one in middle-aged and one in senior males and females, demonstrated the herb’s promotion of healthy fitness, vitality, and vigor concomitant with an increase in free testosterone and a decline in SHBG.[16,17] In summary, it appears that the combination of these two herbs supports healthytestosterone levels in men and women which, in turn, supports vitality, virility, and vigor. References 1. Korenman SG, Morley JE, Mooradian AD, et al. Secondary hypogonadism in older men: its relation to impotence. J Clin Endocrinol Metab. 1990 Oct;71(4):963-969. [PMID: 2205629]2. Vermeulen A, Kaufman JM. Diagnosis of Hypogonadism in the aging male. Aging Male. 2002 Sept;5(3):170-6. [PMID: 12471777]3. Beauchet O. Testosterone and cognitive function: current clinical evidence of a relationship. Eur J Endocrinol. 2006 Dec;155(6):773-81. [PMID: 17132744]4. Wahjoepramono EJ, Asih PR, Aniwiyanti V, et al. The effects of testosterone supplementation on cognitive functioning in older men. CNS Neurol Disord Drug Targets. 2016;15(3):337-43. [PMID: 26553159]5. Davis SR, Wahlin-Jacobsen S. Testosterone in women—the clinical significance. Lancet Diabetes Endocrinol. 2015 Dec;3(12):980-92. [PMID: 26358173]6. Mayo Clinic. Test ID: TTFB. Testosterone, Total, Bioavailable, and Free, Serum. http://www.mayomedicallaboratories.com/test-catalog/Clinical+and+Interpretive/83686. Accessed April 20, 2017.7. Pandit S, Biswas S, Jana S, et al. Clinical evaluation of purified Shilajit on testosterone levels in healthy volunteers. Andrologia. 2015 Jun;48(5);570-5.[PMID: 26395129]8. Surapaneni DK, Adapa SR, Preeti K, et al. Shilajit attenuates behavioral symptoms of chronic fatigue syndrome by modulating the hypothalamicpituitary-adrenal axis and mitochondrial bioenergetics in rats. J Ethnopharmacol. 2012 Aug 30;143(1):91-9. [PMID: 22771318]9. Bucci LR. Selected herbals and human exercise performance. Am J Clin Nutr. 2000 Aug;72(2 Suppl):624S-36S. [PMID: 10919969] 10. Stohs SJ. Safety and efficacy of shilajit (mumie, moomiyo). Phytother Res. 2014 Apr;28(4):475-9. [PMID: 23733436]11. Carrasco-Gallardo C, Guzmán L, Maccioni RB. Shilajit: a natural phytocomplex with potential procognitive activity. Int J Alzheimers Dis. 2012;2012:674142. [PMID: 22482077]12. Biswas TK, Pandit S, Mondal S, et al. Clinical evaluation of spermatogenic activity of processed shilajit in oligospermia. Andrologia. 2010 Feb;42(1):48-56). [PMID: 20078516]13. Das A, Datta S, Rhea B, et al. The human skeletal muscle transcriptome in response to oral shilajit supplementation. J Med Food. 2016 Jul;19(7):701-9. [PMID: 27414521]14. Kotirum S, Ismail SB, Chaiyakunapruk N. Efficacy of tongkat ali (Eurycoma longifolia) on erectile function improvement: systematic review and metaanalysis of randomized controlled trials. Complement Ther Med. 2015 Oct;23(5):693-8. [PMID: 26365449]15. Tambi MI, Kadir AB. LJ100, a potent adaptogen, maintains healthy aging in men. Int J Androl. 2005;28(suppl 1): 25-44.16. Sarina MY. Effects of strength training and LJ100 supplementation on strength and muscle size in middle-aged women. Presented at: 4th Asia-Pacific Conference on Exercise and Sport Science & 8th International Sports ScienceConference; July 15-17, 2009; Malaysia.17. Henkel RR, Wang R, Bassett SH, et al. Tongkat ali as a potential herbal supplement for physically active male and female seniors—a pilot study. Phytother Res. 2014 Apr;28(4),544–550. [PMID: 23754792]

Brain Boost+ is a powerful combination of paraxanthine, alpha-GPC, lion’s mane, N-acetyl L-tyrosine (NALT) and L-Theanine help to increase energy levels, cognitive function, motivation, and focus all while reducing fatigue. Brain Boost+ may also aid in the prevention of age-related cognitive decline and has neuroprotective properties without the jitters or crash.  The ingredients included in Brain Boost+ have shown positive changes in brain wave activity specifically delta and theta waves which are associated with focus and decision making under pressure, making it the ideal formula to utilize when needing a desired edge.  Paraxanthine (enfinity®) is caffeine’s primary metabolite in the human body, contributing to the vast majority of caffeine’s beneficial effects. It is a central nervous system stimulant without the toxicity associated with caffeine and has shown greater benefits than caffeine itself. Caffeine has numerous issues with the gene (CYP1A2, caffeine metabolizer gene), where some are slow metabolizers and deal with much of the side effects and fast metabolizers get little of the benefits.  Only about 30% are ideal metabolizers of caffeine leading to much diversity in how it is experienced. When ingested, enfinity® functions more consistently than caffeine, leading to fewer side effects, greater enjoyability, improved mood, and a more focused mindset.  Multiple studies have shown those benefits to include:  Energy, focus, and wakeful clarity. Enhanced mood and sense of wellbeing. Neuroprotective cognitive accelerant. Improved reaction time and reduced mental errors. Increased caloric expenditure and thermogenesis. Significantly lessened side effects of caffeine with dramatically reduced toxicity. More consistent results: eliminates caffeine’s genetic variability, reducing crashes and anxiety. Alpha-GPC or Alpha-Glycerophoscholine, is a natural compound found in the brain that also exists in small amounts in certain foods.  It’s known for its potential cognitive enhancement and physical performance properties. GeniusPure®Alpha-GPC is a new breakthrough version, 90% yield that is engineered to be hygroscopically stable. Various studies show alpha-GPC supports cognitive function, memory and learning.  Alpha-GPC is a precursor to acetylcholine, a neurotransmitter critical for brain health and crosses the blood-brain barrier.  Lion’s Mane (Hericium erinaceus) is a type of mushroom that has been used in traditional medicine for its potential health benefits especially for the brain.  Lion’s Mane contains compounds that may stimulate the production of nerve growth factor (NGF) in the brain.  NGF is involved in the growth, maintenance, and survival of neurons.  By promoting NGF production, Lion’s Mane may support brain health and cognitive function. N-acetyl L-tyrosine (NALT) is a modified form of the amino acid L-tyrosine.  Tyrosine is a precursor to several important neurotransmitters, including dopamine, norepinephrine, and epinephrine.  These neurotransmitters play key roles in mood regulation, focus, attention, stress support and cognitive function. L-Theanine is an amino acid known for its calming effects and potential benefits for relaxation, focus and cognitive function.   It is known to have a synergistic effect when paired with paraxanthine promoting alertness and focus without the jittery side effects often associated with caffeine use. L-Theanine can cross the blood-brain barrier and affect various neurotransmitters in the brain such as GABA, serotonin and dopamine. It is also known to increase alpha brain wave activity which is associated with a relaxed but alert mental state.

BPC+PEA 500 is a synergistic blend of highly orally bio-available BPC-157 (Arginine Salt) with Palmitoylethanolamide (PEA) and added Salcaprozate sodium (SNAC) for enhanced absorption.  This is an ideal formula for anyone looking to support full body repair and regeneration. The peptide BPC-157 is a pentadecapeptide made up of 15 amino acids that is derived from human gastric juice. It has a molecular weight of 2212 daltons and its sequence is: Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val. BPC-157 is also known as the “Wolverine” peptide, for its ability to help support repair and recovery, many have also found that it’s helped support gut issues, gastric reflux, depression, performance, and more.  BPC-157 has been studied for a variety of topics and has shown to be helpful in many areas such as: tendinopathy, gastric ulcers, general inflammation, and even neuroprotection. BPC-157 seems to work by interacting with our cells’ systems that are responsible for growth and repair, thus helping the body to heal itself. One of the most exciting potential benefits of BPC-157 is its ability to help with tendon repair. Tendons are the tough, fibrous tissues that connect our muscles to our bones and are essential for movement. However, tendons are also susceptible to injury and can often be slow to heal. This is where BPC-157 comes in; by aiding in the repair and regeneration of damaged tendons, BPC-157 could potentially help reduce recovery time and improve outcomes following an injury. BPC-157 has also been shown to be beneficial in supporting the healing of gastric ulcers. Gastric ulcers are a type of peptic ulcer that develops in the lining of the stomach. They are a common and often painful condition that can be difficult to treat. However, BPC-157 has been shown to promote healing of gastric ulcers and improve symptoms. There is also some evidence to suggest that BPC-157 may be helpful in supporting inflammatory bowel disease (IBD). IBD is a chronic condition that causes inflammation of the digestive tract. Symptoms can include abdominal pain, diarrhea, and weight loss. BPC-157 has been shown to reduce inflammation and improve symptoms in animal models of IBD. Overall, BPC-157 appears to be a promising compound with the potential to support a variety of gastrointestinal disorders.  One of the best things about BPC-157 is that it is orally bioavailable, particularly the arginate salt we use, is extremely stable.   We wanted to make sure that oral bioavailability was maximized which is why we included a molecule called SNAC in our formulation. Salcaprozate sodium, or SNAC, is one of the most advanced intestinal permeation enhancers that have been tested in clinical trials for oral delivery of macromolecules. It was originally designed for the oral delivery of insulin. In one study, SNAC increased the absorption of a peptide (a short chain of amino acids) by nine-fold without affecting tight junctions.  Healthgevity's formulation includes an optimal ratio of salcaprozate sodium to our active ingredients. This combination results in exceptional oral absorption of this combination without compromising its stability or efficacy. Palmitoylethanolamide (PEA) is an 18-carbon long- chain fatty acid. Nobel Prize winner Levi-Montalcini identified PEA as a naturally occurring molecule, describing its value in treating chronic infections and pain. Following her discovery, hundreds of scientific studies have been published to show that it is very effective and safe to use. PEA is thought to work by supporting the inflammatory response through the PPAR-a receptor, COX-2 and through effects on NF-kappaB signaling while also by restoring balance in the endocannabinoid system. Its mechanism of action is similar to that of non-steroidal anti-inflammatory drugs (NSAIDs). Palmitoylethanolamide (PEA) is the body’s go-to- molecule and is made on demand when required under disease conditions.  This naturally occurs to help resolve inflammation and pain to restore the body to a normal, health state. Due to its ubiquitous nature and presence in all cells, PEA has wide-ranging therapeutic applications. Some of the most common clinical applications are analgesic effects, chronic pain, and inflammation support. PEA has anti-inflammatory effects on the body by inhibiting the production of pro-inflammatory cytokines and by reducing the activity of activated microglia cells. It is also thought to reduce pain by modulating the neurotransmitters involved in pain signaling. In addition to its analgesic and anti-inflammatory effects, PEA is also thought to offer neuroprotection by reducing the levels of reactive oxygen species and by modulating cell death pathways. It has also been shown to improve cognitive function in animal models of Alzheimer's disease. The endocannabinoid system is involved in a wide range of physiological processes, including digestion. The role of the endocannabinoid system in the gut has been studied extensively and it is now well-established that cannabinoids modulate gastrointestinal motility, secretion and inflammation. PEA is one of the most abundant endocannabinoids in the gut and is thought to play a key role in gut-brain axis. The endocannabinoid system is known to be involved in various digestive disorders, such as inflammatory bowel disease (IBD), irritable bowel syndrome (IBS) and gastroesophageal reflux disease (GERD). Several studies have shown that PEA is effective in reducing symptoms of IBS, such as abdominal pain and bloating. A recent clinical trial showed that a PEA-based product was able to significantly reduce IBS symptoms in patients who did not respond to standard therapy. PEA has also been shown to be effective in supporting other digestive disorders such as GERD and IBD. In a clinical trial, PEA was able to significantly reduce symptoms of GERD, such as heartburn and acid reflux.   *This item may take longer to ship*

BPC-157 is a pentadecapeptide made up of 15 amino acids that is derived from human gastric juice. It has a molecular weight of 2212 daltons and its sequence is: Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val. BPC-157 is also known as the “Wolverine” peptide, for its ability to help support repair and recovery, many have also found that it’s helped support gut issues, gastric reflux, depression, performance, and more.  BPC-157 has been studied for a variety of topics and has shown to be helpful in many areas such as: tendinopathy, gastric ulcers, general inflammation, and even neuroprotection. BPC-157 seems to work by interacting with our cells’ systems that are responsible for growth and repair, thus helping the body to heal itself. One of the most exciting potential benefits of BPC-157 is its ability to help with tendon repair. Tendons are the tough, fibrous tissues that connect our muscles to our bones and are essential for movement. However, tendons are also susceptible to injury and can often be slow to heal. This is where BPC-157 comes in; by aiding in the repair and regeneration of damaged tendons, BPC-157 could potentially help reduce recovery time and improve outcomes following an injury. BPC-157 has also been shown to be beneficial in supporting the healing of gastric ulcers. Gastric ulcers are a type of peptic ulcer that develops in the lining of the stomach. They are a common and often painful condition that can be difficult to treat. However, BPC-157 has been shown to promote healing of gastric ulcers and improve symptoms. There is also some evidence to suggest that BPC-157 may be helpful in supporting inflammatory bowel disease (IBD). IBD is a chronic condition that causes inflammation of the digestive tract. Symptoms can include abdominal pain, diarrhea, and weight loss. BPC-157 has been shown to reduce inflammation and improve symptoms in animal models of IBD. Overall, BPC-157 appears to be a promising compound with the potential to support a variety of gastrointestinal disorders.  One of the best things about BPC-157 is that it is orally bioavailable, particularly the arginate salt we use, is extremely stable.   We wanted to make sure that oral bioavailability was maximized which is why we included a molecule called SNAC in our formulation. Salcaprozate sodium, or SNAC, is one of the most advanced intestinal permeation enhancers that have been tested in clinical trials for oral delivery of macromolecules. It was originally designed for the oral delivery of insulin. In one study, SNAC increased the absorption of a peptide (a short chain of amino acids) by nine-fold without affecting tight junctions.  Healthgevity's formulation includes an optimal ratio of salcaprozate sodium to our active ingredients. This combination results in exceptional oral absorption of this combination without compromising its stability or efficacy. REFERENCES BPC-157: Staresinic M, Japjec M, Vranes H, Prtoric A, Zizek H, Krezic I, Gojkovic S, Smoday IM, Oroz K, Staresinic E, Dretar V, Yago H, Milavic M, Sikiric S, Lovric E, Batelja Vuletic L, Simeon P, Dobric I, Strbe S, Kokot A, Vlainic J, Blagaic AB, Skrtic A, Seiwerth S, Sikiric P. Stable Gastric Pentadecapeptide BPC 157 and Striated, Smooth, and Heart Muscle. Biomedicines. 2022; 10(12):3221. https://doi.org/10.3390/biomedicines10123221 Seiwerth, Sven et al. “BPC 157 and Standard Angiogenic Growth Factors. Gastrointestinal Tract Healing, Lessons from Tendon, Ligament, Muscle and Bone Healing.” Current pharmaceutical design vol. 24,18 (2018): 1972-1989. doi:10.2174/1381612824666180712110447 Gwyer, Daniel et al. “Gastric pentadecapeptide body protection compound BPC 157 and its role in accelerating musculoskeletal soft tissue healing.” Cell and tissue research vol. 377,2 (2019): 153-159. doi:10.1007/s00441-019-03016-8 Chang, Chung-Hsun et al. “The promoting effect of pentadecapeptide BPC 157 on tendon healing involves tendon outgrowth, cell survival, and cell migration.” Journal of applied physiology (Bethesda, Md. : 1985) vol. 110,3 (2011): 774-80. doi:10.1152/japplphysiol.00945.2010 Sikiric, Predrag et al. “Brain-gut Axis and Pentadecapeptide BPC 157: Theoretical and Practical Implications.” Current neuropharmacology vol. 14,8 (2016): 857-865. doi:10.2174/1570159x13666160502153022  Seiwerth, S., Sikiric, P., Grabarevic, Z., Zoricic, I., Hanzevacki, M., Ljubanovic, D., … Kolega, Z. (1997). BPC 157’s effect on Healing. Journal of Physiology Paris, 91(3–5), 173–178. https://doi.org/10.1016/S0928-4257(97)89480-6 Salcaprozate sodium (SNAC): Twarog, Caroline et al. “Intestinal Permeation Enhancers for Oral Delivery of Macromolecules: A Comparison between Salcaprozate Sodium (SNAC) and Sodium Caprate (C10).” Pharmaceutics vol. 11,2 78. 13 Feb. 2019, doi:10.3390/pharmaceutics11020078 Zhu Q, Chen Z, Paul PK, Lu Y, Wu W, Qi J. Oral delivery of proteins and peptides: Challenges, status quo and future perspectives. Acta Pharm Sin B. 2021 Aug;11(8):2416-2448. doi: 10.1016/j.apsb.2021.04.001. Epub 2021 Apr 29. PMID: 34522593; PMCID: PMC8424290. Aroda, V.R., Blonde, L. & Pratley, R.E. A new era for oral peptides: SNAC and the development of oral semaglutide for the treatment of type 2 diabetes. Rev Endocr Metab Disord 23, 979–994 (2022). https://doi.org/10.1007/s11154-022-09735-8

Pendulum Akkermansia contains the strain Akkermansia muciniphila, the prebiotic inulin and is on-GMO verified, vegan, gluten-free, sourced & manufactured in the USA. Research indicates that Akkermansia nurtures the gut microbiome, optimizes the balance of the gut-mucus layer, and maintains a healthy ecosystem of beneficial bacteria in the gut microbiome. This keystone strain is found in over 1,000+ science publications and is known as the next-generation strain at the forefront of gut health. Strain in the product: Akkermansia muciniphila WB-STR-0001 AFU Information: 100 million AFUs per capsule

Each spray gives a dose of propolis, oregano oil, eucalyptus, xylitol, and saline.

Recommended Dosage: CAUTION: Dangerously hot for oral consumption. Mixing with water before consumption is highly recommended. ORGANIC See MORE HERE *This item may take longer to ship out*

Udo’s Oil® Omega 3 • 6 • 9 Blend is a foundational oil that provides the omega-3 and omega-6 essential fatty acids (EFAs) the body needs but cannot make on its own – they must be obtained from our diet. This plant-sourced, organic unrefined oil blend is designed to provide the ideal 2-to-1 ratio of omega-3 and omega-6 fatty acids. Omega-9, a monounsaturated fatty acid is featured in the Mediterranean diet, touted as one of the healthiest diets known for its benefits to cardiovascular health. Award-winning Udo’s Oil® Omega 3 • 6 • 9 Blend contains all the good fats you need without the bad fats you should avoid, with natural, unrefined oils from fresh, certified organic flax, sunflower, sesame, and evening primrose seeds as well as oils from coconut, and oat and rice bran. • Each 15 mL serving of Udo’s Oil® Omega 3 • 6 • 9 Blend provides 6 grams of omega-3 and 3 grams of omega-6 fatty acids• Unrefined and freshly pressed in a state-of-the-art, low light, temperature controlled and oxygen-free environment to optimize freshness and provide maximum nutritional value• Made exclusively with 100% sustainable, plant-based ingredients• Non-GMO + Organic + Vegan + Keto-Friendly