Biotics Research

Why you may need VasculoSirt: Vascular aging is characterized by progressive arterial stiffness, loss of arterial elasticity and arterial compliance from a myriad of structural and functional changes. VasculoSirt’s revolutionary nutritional formula is designed to: Slow vascular aging Promote vascular and heart health Support longevity and metabolic function Provide support for healthy blood pressure, cholesterol, glucose and insulin levels within normal ranges Support sirtuin activity   Why we recommend VasculoSirt from Biotics Research: Not only is VasculoSirt one of the most comprehensive cardiovascular and antiaging supplements available, but each bottle of VasculoSirt takes the place of up to 12 separate supplements, providing distinct cost and convenience advantages for your patients. Dr. Mark Houston, Associate Clinical Professor of Medicine at Vanderbilt Medical School and Director of Hypertension Institute and Vascular Biology in Nashville, in conjunction with Biotics Research Corporation developed VasculoSirt, a state of the art nutritional supplement amalgamating the optimal nutrient levels used in a wide variety of clinical studies. In keeping with Biotics Research Corporation’s dedication to providing superior leading-edge supplements, each serving of VasculoSirt supplies 50 mg of Resveratrol (Trans-Resveratrol), 50 mg of R-Lipoic Acid, 250 mg of EGCG (Epigallocatechin Gallate), and 50 mg of Coenzyme Q10 (emulsified for increased uptake and utilization), along with 23 other vitamins and nutrients that have been shown to support a wide variety of cardiovascular processes. VasculoSirt was released for clinical use in August 2007 and is the first nutraceutical supplement designed to promote vascular and heart health, slow vascular aging, improve endothelial function and arterial compliance, support normal healthy blood pressure levels, metabolic function via enhanced mitochondria support, and possibly normalize atherosclerotic markers. Over the past five plus years, VasculoSirt ’s use has been clinically evaluated in well over 1,000 patients at the Hypertension Institute. Dr. Mark Houston has found that when VasculoSirt is used with an optimal program of nutrition, exercise, and weight management, improvements in vascular health were typically noted.

*This item will take a few extra days to ship* GTA® provides supplemental support for healthy endocrine function. It provides glandular (porcine), trace mineral and antioxidant enzyme support, and is fortified with the minerals rubidium and selenium.  

This product is on our Fire Sale of expired/soon to be expired products. But rest assured, they are still as potent for at least another 12-24 months! Cytozyme Orchic™ (bovine) supplies glandular specific support as Orchic Concentrate, combined with SOD and catalase, important antioxidant enzymes. Orchic concentrate is made from cattle testicles. 

Optimal EFAs®-BC supplies a unique balance of omega-3, -6, and -9 fatty acids by using the highest quality fish, flaxseed, and blackcurrant seed oils. Each capsule provides optimal ratios of alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), gamma-linolenic acid (GLA) and oleic fatty acids. Optimal EFAs®-BC contains EPA and DHA sourced from a strategically-placed facility in the far South Pacific Ocean off the coast of Chile, guaranteeing the freshest fish oil available with full traceability and unparalleled purity.

Source of supplemental selenium in a liquid form, with each drop supplying 95 mcg of elemental selenium, an essential trace mineral providing anti-oxidant activity. Selenium is key to the production of glutathione peroxidases.    *This item may take longer to ship*

*This item might take a few extra days to ship*   Super Phosphozyme™ is a source of organic phosphorus and orthophosphoric acid, along with RNA, inositol and vitamin C. It may be considered when the need for supplemental phosphorus is indicated. 

Vitamin B6 (pyridoxine) toxicity has been reported at dosages above 300 mg per day for extended periods. However, the biologically active form of vitamin B6, pyridoxal‐5‐phosphate (P5P), has no reported toxicity. Therefore, P5P is the preferred form of vitamin B6 for higher utilization. While Vitamin B1 is widely distributed in the food chain, highly refined foods are virtually absent in thiamin, thus a diet high in these foods will ultimately be low in thiamin. Functionally, thiamin is a part of the coenzyme thiamin pyrophosphate (TPP), also known as cocarboxyase, and is a required component in the metabolism of carbohydrates as a part of the coenzyme thiamine cocarboxylase. Specifically, TPP “is required for the oxidative decarboxylation of pyruvate to form acetyl‐coenzyme A, providing entry of oxidizable substrate(s) into the Krebs cycle for the generation of energy. Additionally, it is also a coenzyme for transketolase, which functions in the pentose phosphate pathway, an alternate pathway for glucose oxidation.” Thiamine is most strongly linked with carbohydrate metabolism, but TPP is also required for the oxidative decarboxylation of other alpha‐keto acids such as alpha‐ketoglutarate and branched‐chain alpha‐keto acids (i.e., 2‐ketocarboxylates) derived from certain amino acids (e.g., valine, isoleucine, leucine). The pyrophosphate ester of thiamine, thiamine diphosphate is a cofactor for enzymatic reactions that cleave alpha‐keto acids. TPP activates the decarboxylation of pyruvate in the pyruvate dehydrogenase complex. Vitamin B1 (thiamin) is also noted for its benefits for inflammation of the nerves (neuritis), and deficiency is associated with “high calorie malnutrition.” Deficiency may be established by determination of the erythrocyte (red blood cell) transketolase activity. Zinc serves as an essential cofactor for greater than seventy (70) enzymes, and participates in binding DNA as a component of the zinc binding proteins (zinc fingers), which consists of a combination of the protein and zinc. Zinc also functions in many other roles in the body, including participation in the role of insulin release. Zinc functions in membrane stabilization, and is part of the bone mineral apatite. Zinc has also been demonstrated to “increase osteogenic effect” via multiple mechanisms, including via cellular proliferation stimulation, increased alkaline phosphatase (ALP) activity, increased synthesis of collagen in osteoblastic cells, and via a concentration increase of cellular collagen. A deficiency in zinc results in a decrease in bone weight, delays growth in bone metabolism, and retards bone growth, development and maintenance. Both in vivo and in vitro studies have also demonstrated that zinc possess stimulatory effects on bone formation and mineralization.

KappArest™ is a proprietary formula designed to downregulate inflammatory pathways, primarily through the inhibition of NF-kappaB, a molecule inside each cell. Many disease conditions are associated with inappropriate activation of nuclear transcription factor kappaB (NF-KappaB). The modulation of NF-KappaB has become a major therapeutic goal in the management of a wide range of illnesses. KappArest™ supplies a broad array of antioxidants and phytonutrient components, demonstrated to suppress the activation of NF-kappaB, and associated kinases, including AP-1. Seven of the eight ingredients have documented activity in suppressing NF-KappaB. Phytolens, a Biotics Research patented extract from lentil, has also demonstrated broad antioxidant properties, and displays potent free radical scavenging ability, resulting in marked benefits on the inflammatory process.

Bio-HPF® is a special digestive support formula supplying a synergistic complement of herbal components. Despite the highly acidic environment of the stomach, H. pylori is able to persist, thought to be due primarily to its characteristic spiral morphology, and its high motility. Acute H. pylori induced gastritis is associated with hypochlorhydria, and colonization is speculated to have the ability to modify the net gastric acidity, by virtue of the substances the bacterium secretes. H. pylori infestation is associated with a dysregulation in the function of the gastric epithelial barrier, as well as with increased epithelial permeability. Additionally, the inflammatory response to H. pylori is well documented, implicated to result in cellular proliferation and gastric mucosal damage. H. pylori components have been demonstrated to act directly on gastric epithelium and to induce an increased release of cytokines. These actions have been primarily attributed to the up-regulation of inflammatory markers, including COX-2 and IL-1β. To curtail this deleterious effect on the gastric mucosa, a comprehensive blend of phytochemical nutrients, known to have a positive impact on the gastrointestinal tissues, may aide in healing and repairing these tissues. Select herbs are recognized as possessing anti-pylori activity, noted to downregulate inflammatory markers associated with H. pylori infestation and correlated to gastric inflammation. Additionally, the use of select herbal components has demonstrated a positive effect in reducing the antigens associated with H. pylori.  *This item may take longer to ship*