B6/B1 Plus Zinc - 90 Capsules

{"id":3798800302144,"title":"B6\/B1 Plus Zinc - 90 Capsules","handle":"b6-b1-plus-zinc-90-capsules","description":"\u003cp\u003e\u003cspan\u003eVitamin B\u003c\/span\u003e\u003cspan\u003e6 \u003c\/span\u003e\u003cspan\u003e(pyridoxine) toxicity has been reported at dosages above 300 mg per day for extended periods. However, the biologically active form of vitamin B\u003c\/span\u003e\u003cspan\u003e6\u003c\/span\u003e\u003cspan\u003e,\u003c\/span\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cdiv class=\"page\" title=\"Page 1\"\u003e\n\u003cdiv class=\"layoutArea\"\u003e\n\u003cdiv class=\"column\"\u003e\n\u003cp\u003e\u003cspan\u003e pyridoxal‐5‐phosphate (P5P), has no reported toxicity. Therefore, P5P is the preferred form of vitamin B\u003c\/span\u003e\u003cspan\u003e6 \u003c\/span\u003e\u003cspan\u003efor higher utilization. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eWhile Vitamin B\u003c\/span\u003e\u003cspan\u003e1 \u003c\/span\u003e\u003cspan\u003eis widely distributed in the food chain, highly refined foods are virtually absent in thiamin, thus a diet high in these foods will ultimately be low in thiamin. Functionally, thiamin is a part of the coenzyme thiamin pyrophosphate (TPP), also known as cocarboxyase, and is a required component in the metabolism of carbohydrates as a part of the coenzyme thiamine cocarboxylase. \u003c\/span\u003e\u003cspan\u003eSpecifically, TPP “is required for the oxidative decarboxylation of pyruvate to form acetyl‐coenzyme A, providing entry of oxidizable substrate(s) into the Krebs cycle for the generation of energy. Additionally, it is also a coenzyme for transketolase, which functions in the pentose phosphate pathway, an alternate pathway for glucose oxidation.”\u003c\/span\u003e\u003c\/p\u003e\n\u003cdiv class=\"page\" title=\"Page 1\"\u003e\n\u003cdiv class=\"layoutArea\"\u003e\n\u003cdiv class=\"column\"\u003e\n\u003cp\u003e\u003cspan\u003eThiamine is most strongly linked with carbohydrate metabolism, but TPP is also required for the oxidative decarboxylation of other alpha‐keto acids such as \u003c\/span\u003ealpha‐ketoglutarate and branched‐chain alpha‐keto acids (i.e., 2‐ketocarboxylates) derived from certain amino acids (e.g., valine, isoleucine, leucine). The pyrophosphate ester of thiamine, thiamine diphosphate is a cofactor for enzymatic reactions that cleave alpha‐keto acids. TPP activates the decarboxylation of pyruvate in the pyruvate dehydrogenase complex.\u003c\/p\u003e\n\u003cdiv class=\"page\" title=\"Page 2\"\u003e\n\u003cdiv class=\"layoutArea\"\u003e\n\u003cdiv class=\"column\"\u003e\n\u003cp\u003e\u003cspan\u003eVitamin B\u003c\/span\u003e\u003cspan\u003e1 \u003c\/span\u003e\u003cspan\u003e(thiamin) is also noted for its benefits for inflammation of the nerves (neuritis), and deficiency is associated with “high calorie malnutrition.” \u003c\/span\u003e\u003cspan\u003eDeficiency may be established by determination of the erythrocyte (red blood cell) transketolase activity. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eZinc serves as an essential cofactor for greater than seventy (70) enzymes, and participates in binding DNA as a component of the zinc binding proteins (zinc fingers), which consists of a combination of the protein and zinc.\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eZinc also functions in many other roles in the body, including participation in the role of insulin release.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eZinc functions in membrane stabilization, and is part of the bone mineral apatite. Zinc has also been demonstrated to “increase osteogenic effect” via\u003cbr\u003emultiple mechanisms, including via cellular proliferation stimulation, increased alkaline phosphatase (ALP) activity, increased synthesis of collagen in osteoblastic cells, and via a concentration increase of cellular collagen.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eA deficiency in zinc results in a decrease in bone weight, delays growth in bone metabolism, and retards bone growth, development and maintenance.\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eBoth \u003c\/span\u003e\u003cspan\u003ein vivo \u003c\/span\u003e\u003cspan\u003eand \u003c\/span\u003e\u003cspan\u003ein vitro \u003c\/span\u003e\u003cspan\u003estudies have also demonstrated that zinc possess stimulatory effects on bone formation and mineralization.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","published_at":"2023-05-17T13:36:47-05:00","created_at":"2019-06-05T09:49:18-05:00","vendor":"Biotics Research","type":"Supplement","tags":["Biotics","Cancer","Genetics","Lyme","Men","Women"],"price":3240,"price_min":3240,"price_max":3240,"available":true,"price_varies":false,"compare_at_price":null,"compare_at_price_min":0,"compare_at_price_max":0,"compare_at_price_varies":false,"variants":[{"id":28978123833408,"title":"Default Title","option1":"Default Title","option2":null,"option3":null,"sku":"210000002097","requires_shipping":true,"taxable":true,"featured_image":null,"available":true,"name":"B6\/B1 Plus Zinc - 90 Capsules","public_title":null,"options":["Default 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B\u003c\/span\u003e\u003cspan\u003e6\u003c\/span\u003e\u003cspan\u003e,\u003c\/span\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cdiv class=\"page\" title=\"Page 1\"\u003e\n\u003cdiv class=\"layoutArea\"\u003e\n\u003cdiv class=\"column\"\u003e\n\u003cp\u003e\u003cspan\u003e pyridoxal‐5‐phosphate (P5P), has no reported toxicity. Therefore, P5P is the preferred form of vitamin B\u003c\/span\u003e\u003cspan\u003e6 \u003c\/span\u003e\u003cspan\u003efor higher utilization. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eWhile Vitamin B\u003c\/span\u003e\u003cspan\u003e1 \u003c\/span\u003e\u003cspan\u003eis widely distributed in the food chain, highly refined foods are virtually absent in thiamin, thus a diet high in these foods will ultimately be low in thiamin. Functionally, thiamin is a part of the coenzyme thiamin pyrophosphate (TPP), also known as cocarboxyase, and is a required component in the metabolism of carbohydrates as a part of the coenzyme thiamine cocarboxylase. \u003c\/span\u003e\u003cspan\u003eSpecifically, TPP “is required for the oxidative decarboxylation of pyruvate to form acetyl‐coenzyme A, providing entry of oxidizable substrate(s) into the Krebs cycle for the generation of energy. Additionally, it is also a coenzyme for transketolase, which functions in the pentose phosphate pathway, an alternate pathway for glucose oxidation.”\u003c\/span\u003e\u003c\/p\u003e\n\u003cdiv class=\"page\" title=\"Page 1\"\u003e\n\u003cdiv class=\"layoutArea\"\u003e\n\u003cdiv class=\"column\"\u003e\n\u003cp\u003e\u003cspan\u003eThiamine is most strongly linked with carbohydrate metabolism, but TPP is also required for the oxidative decarboxylation of other alpha‐keto acids such as \u003c\/span\u003ealpha‐ketoglutarate and branched‐chain alpha‐keto acids (i.e., 2‐ketocarboxylates) derived from certain amino acids (e.g., valine, isoleucine, leucine). The pyrophosphate ester of thiamine, thiamine diphosphate is a cofactor for enzymatic reactions that cleave alpha‐keto acids. TPP activates the decarboxylation of pyruvate in the pyruvate dehydrogenase complex.\u003c\/p\u003e\n\u003cdiv class=\"page\" title=\"Page 2\"\u003e\n\u003cdiv class=\"layoutArea\"\u003e\n\u003cdiv class=\"column\"\u003e\n\u003cp\u003e\u003cspan\u003eVitamin B\u003c\/span\u003e\u003cspan\u003e1 \u003c\/span\u003e\u003cspan\u003e(thiamin) is also noted for its benefits for inflammation of the nerves (neuritis), and deficiency is associated with “high calorie malnutrition.” \u003c\/span\u003e\u003cspan\u003eDeficiency may be established by determination of the erythrocyte (red blood cell) transketolase activity. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eZinc serves as an essential cofactor for greater than seventy (70) enzymes, and participates in binding DNA as a component of the zinc binding proteins (zinc fingers), which consists of a combination of the protein and zinc.\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eZinc also functions in many other roles in the body, including participation in the role of insulin release.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eZinc functions in membrane stabilization, and is part of the bone mineral apatite. Zinc has also been demonstrated to “increase osteogenic effect” via\u003cbr\u003emultiple mechanisms, including via cellular proliferation stimulation, increased alkaline phosphatase (ALP) activity, increased synthesis of collagen in osteoblastic cells, and via a concentration increase of cellular collagen.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eA deficiency in zinc results in a decrease in bone weight, delays growth in bone metabolism, and retards bone growth, development and maintenance.\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan\u003eBoth \u003c\/span\u003e\u003cspan\u003ein vivo \u003c\/span\u003e\u003cspan\u003eand \u003c\/span\u003e\u003cspan\u003ein vitro \u003c\/span\u003e\u003cspan\u003estudies have also demonstrated that zinc possess stimulatory effects on bone formation and mineralization.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e\u003c\/h3\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e"}