Conners Originals Vira Clear features three herbs that have been used traditionally for immune support and stimulation. Contemporary research on these herbs - andrographis, licorice root, and indigowoad - confirms the wisdom of their historical use. Vira Clear may be especially helpful in supporting cytokine balance and respiratory function.
- Andrographis extract
- Indigowoad 10:1 extract
- Licorice extract
Does Not Contain:
Wheat, gluten, yeast, soy, animal or dairy products, fish, shellfish, peanuts, tree nuts, egg, ingredients derived from genetically modified organisms (GMOs), artificial colors, artificial sweeteners, or artificial preservatives.
- helps the immune system target viral infections
- supports upper respiratory health and immune response
- increases in white blood cell and lymphocyte counts
- maintains a healthy mucous membrane
- stimulates healthy mucous production
- supports eicosanoid balance
- can increase spleen weight
- increases the number of circulating white blood cells, lymphocytes in particular
- scavenges superoxide free radicals
Vira Clear comprises three herbs that have been used to support the body’s immune system:
Andrographis Extract (Andrographis paniculata) - has been used widely in traditional medical systems as a bitter herb that works quickly to support upper respiratory health and immune response. The herb has been used to support temperature regulation, respiratory health, immune function, and cytokine and eicosanoid balance. A randomized, double-blind, placebo-controlled study investigated the use of 1200 mg/ day (standardized to 4% andrographolides) in 158 adult patients. Results revealed that individuals receiving the herb had a significant improvement in several of the parameters measured when compared to placebo. A “high degree of effectiveness” was observed by day two of treatment.
Research on andrographolide, a major constituent of andrographis, suggests that this bioactive component supports immune activity in human cells by increasing proliferation of lymphocytes, production of interleukin-2, tumor necrosis factor-alpha, and cluster of differentiation (CD) marker expression. A phase I dose-escalating trial of andrographolide was conducted in a select group of individuals. A significant rise in mean CD4(+) lymphocytes was observed in individuals receiving 10 mg/kg andrographolide (p = 0.002). It was noted in the study that prolonged use of concentrated andrographolide may lead to dose-related (5-10 mg/kg) adverse effects for some individuals, a point that should be considered when calculating individual dosing. Acute toxicology studies in rodents noted no observed adverse effects at doses up to 5 g/ kg of andrographolide. Researchers did note significant increases in white blood cell and lymphocyte counts as well as a reduction in urea, suggesting that andrographolide had immune-stimulant and renal protective effects. Andrographolide is standardized to 50% in Vira Clear.
Licorice Root Extract (Glycyrrhiza glabra) - Medicinal use of licorice dates back to ancient Greece, China, India, and Egypt. Contemporary research suggests that its active component glycyrrhizin supports the human immune system in the presence of pathogens. A 2004 study found that glycyrrhizin more effectively supported immune function than other compounds studied (ribavirin, 6-azauridine, pyrazofurin, and mycophenolic acid). Research suggests that mechanisms of action for glycyrrhizin include induction of T-cell interferon-gamma and interference with the pathogen’s membrane.
Indigowoad 10:1 Root Extract (Isatis indigotica) - Indigowoad is commonly used to support the immune system and upper respiratory tract. A closer look at the mechanism of action for indigowoad root extract in animals revealed that the extract significantly increased spleen weight as well as the number of circulating white blood cells, lymphocytes in particular. The same study found that the indigowoad extract stimulated macrophage phagocytic activity and reduced the suppressive effect that hydrocortisone has on the immune system. A human neutrophil cell study indicated that the isaindigotone derivative of I indigotica was able to scavenge superoxide free radicals and inhibit 5-lipoxygenase and leukotriene B(4) metabolism, ultimately supporting a healthy eicosanoid balance.
Take 2 capsules daily, or as directed by your healthcare practitioner. Do not open capsule before consumption. Recommended for short-term use.
Consult your healthcare practitioner prior to use. Individuals taking medication should discuss potential interactions with their healthcare practitioner. Consult your healthcare practitioner if you have uncontrolled hypertension. Do not use if tamper seal is damaged.