{"id":9036610207964,"title":"NAD SUPPORT+ 60 Caps *","handle":"nad-support-60-caps","description":"\u003cp\u003e \u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp class=\"MsoNormal\"\u003eIntroducing a powerful, cutting-edge supplement designed to support and enhance healthy NAD+ levels—vital for energy, cellular repair, and overall vitality. This innovative formula combines NMN (Nicotinamide Mononucleotide), a precursor to NAD+, with TMG(Trimethylglycine), which helps optimize methylation and support detoxification. Added Pterostilbene, a potent antioxidant, helps protect cells from oxidative stress while promoting healthy aging, and Apigenin, a natural flavonoid, further supports cellular health and cognitive function. Together, these ingredients work synergistically to elevate NAD+ levels, boost energy support, improve metabolic function, and promote longevity.\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cb\u003e\u003cspan\u003eNicotinamide Mononucleotide: 1,000mg\u003c\/span\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cb\u003e\u003cspan\u003eKey Benefits:\u003c\/span\u003e\u003c\/b\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli class=\"MsoNormal\"\u003e\n\u003cb\u003e\u003cspan\u003eBoosts NAD+ Levels:\u003c\/span\u003e\u003c\/b\u003e\u003cspan\u003e Nicotinamide Mononucleotide is a direct precursor to NAD+, an essential molecule for energy production and cellular repair. By replenishing NAD+, NMN combats age-related declines in mitochondrial function and supports optimal metabolism.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli class=\"MsoNormal\"\u003e\n\u003cb\u003e\u003cspan\u003eSupports Longevity Pathways:\u003c\/span\u003e\u003c\/b\u003e\u003cspan\u003e Nicotinamide Mononucleotide activates sirtuins, enzymes that regulate DNA repair, inflammation control, and cellular health.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli class=\"MsoNormal\"\u003e\n\u003cb\u003e\u003cspan\u003eEnhances Physical and Cognitive Performance:\u003c\/span\u003e\u003c\/b\u003e\u003cspan\u003e Higher NAD+ levels improve endurance, recovery, and brain function.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cb\u003e\u003cspan\u003eScientific Evidence:\u003c\/span\u003e\u003c\/b\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli class=\"MsoNormal\"\u003e\n\u003cspan\u003eStudies show Nicotinamide Mononucleotide supplementation restores NAD+ levels, improving mitochondrial function and lifespan in animal models\u003c\/span\u003e\u003cspan\u003e【\u003c\/span\u003e\u003cspan\u003e1\u003c\/span\u003e\u003cspan\u003e】\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli class=\"MsoNormal\"\u003e\n\u003cspan\u003eHuman trials demonstrate Nicotinamide Mononucleotide's ability to enhance blood flow and muscle oxygenation\u003c\/span\u003e\u003cspan\u003e【\u003c\/span\u003e\u003cspan\u003e2\u003c\/span\u003e\u003cspan\u003e】\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cdiv class=\"MsoNormal\" align=\"center\"\u003e\u003chr size=\"0\" width=\"100%\" align=\"center\"\u003e\u003c\/div\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cb\u003e\u003cspan\u003eTrimethylglycine (TMG) (as Betaine Anhydrous): 500mg\u003c\/span\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cb\u003e\u003cspan\u003eKey Benefits:\u003c\/span\u003e\u003c\/b\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli class=\"MsoNormal\"\u003e\n\u003cb\u003e\u003cspan\u003eSupports Methylation Processes:\u003c\/span\u003e\u003c\/b\u003e\u003cspan\u003e TMG acts as a methyl donor, critical for processing homocysteine into methionine. This helps maintain healthy DNA and supports NMN's conversion into NAD+.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli class=\"MsoNormal\"\u003e\n\u003cb\u003e\u003cspan\u003eProtects Cells from Stress:\u003c\/span\u003e\u003c\/b\u003e\u003cspan\u003e TMG stabilizes proteins and cell membranes under osmotic stress, ensuring cellular integrity.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli class=\"MsoNormal\"\u003e\n\u003cb\u003e\u003cspan\u003eSupports Heart and Liver Health:\u003c\/span\u003e\u003c\/b\u003e\u003cspan\u003e Helps support homocysteine levels and cardiovascular risk factors.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cb\u003e\u003cspan\u003eScientific Evidence:\u003c\/span\u003e\u003c\/b\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli class=\"MsoNormal\"\u003e\n\u003cspan\u003eResearch highlights TMG’s role in enhancing cellular methylation and metabolic efficiency\u003c\/span\u003e\u003cspan\u003e【\u003c\/span\u003e\u003cspan\u003e3\u003c\/span\u003e\u003cspan\u003e】【4】\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli class=\"MsoNormal\"\u003e\n\u003cspan\u003eTMG improves physical endurance and energy production in athletes\u003c\/span\u003e\u003cspan\u003e【\u003c\/span\u003e\u003cspan\u003e5\u003c\/span\u003e\u003cspan\u003e】\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cdiv class=\"MsoNormal\" align=\"center\"\u003e\u003chr size=\"0\" width=\"100%\" align=\"center\"\u003e\u003c\/div\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cb\u003e\u003cspan\u003ePterostilbene: 50mg \u003c\/span\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cb\u003e\u003cspan\u003eKey Benefits:\u003c\/span\u003e\u003c\/b\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli class=\"MsoNormal\"\u003e\n\u003cb\u003e\u003cspan\u003eAntioxidant Powerhouse:\u003c\/span\u003e\u003c\/b\u003e\u003cspan\u003e A more bioavailable analog of resveratrol, pterostilbene neutralizes free radicals and protects against oxidative damage.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli class=\"MsoNormal\"\u003e\n\u003cb\u003e\u003cspan\u003eActivates Sirtuins:\u003c\/span\u003e\u003c\/b\u003e\u003cspan\u003e Supports longevity by enhancing sirtuin activity, which depends on NAD+.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli class=\"MsoNormal\"\u003e\n\u003cb\u003e\u003cspan\u003eSupports Cognitive Function:\u003c\/span\u003e\u003c\/b\u003e\u003cspan\u003e Protects brain cells from age-related decline, enhancing memory and focus.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cb\u003e\u003cspan\u003eScientific Evidence:\u003c\/span\u003e\u003c\/b\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli class=\"MsoNormal\"\u003e\n\u003cspan\u003eStudies suggest pterostilbene is more bioavailable and effective than resveratrol at promoting cellular health\u003c\/span\u003e\u003cspan\u003e【\u003c\/span\u003e\u003cspan\u003e6\u003c\/span\u003e\u003cspan\u003e】【\u003c\/span\u003e\u003cspan\u003e7\u003c\/span\u003e\u003cspan\u003e】\u003c\/span\u003e\u003cspan\u003e.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli class=\"MsoNormal\"\u003e\n\u003cspan\u003ePterostilbene has anti-inflammatory effects, supporting cardiovascular and brain health\u003c\/span\u003e\u003cspan\u003e【\u003c\/span\u003e\u003cspan\u003e8\u003c\/span\u003e\u003cspan\u003e】\u003c\/span\u003e\u003cspan\u003e.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cdiv class=\"MsoNormal\" align=\"center\"\u003e\u003chr size=\"0\" width=\"100%\" align=\"center\"\u003e\u003c\/div\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cb\u003e\u003cspan\u003eApigenin: 50mg \u003c\/span\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cb\u003e\u003cspan\u003eKey Benefits:\u003c\/span\u003e\u003c\/b\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli class=\"MsoNormal\"\u003e\n\u003cb\u003e\u003cspan\u003eInhibits CD38:\u003c\/span\u003e\u003c\/b\u003e\u003cspan\u003e Apigenin blocks CD38, an enzyme that depletes NAD+ levels, ensuring more NAD+ is available for critical cellular processes.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli class=\"MsoNormal\"\u003e\n\u003cb\u003e\u003cspan\u003eAnti-Inflammatory Properties:\u003c\/span\u003e\u003c\/b\u003e\u003cspan\u003e Supports chronic inflammation, a key driver of aging and age-related diseases.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli class=\"MsoNormal\"\u003e\n\u003cb\u003e\u003cspan\u003eProtects Against Oxidative Stress:\u003c\/span\u003e\u003c\/b\u003e\u003cspan\u003e Enhances cellular resilience by reducing oxidative damage to DNA, proteins, and lipids.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cb\u003e\u003cspan\u003eScientific Evidence:\u003c\/span\u003e\u003c\/b\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli class=\"MsoNormal\"\u003e\n\u003cspan\u003eResearch confirms apigenin’s ability to inhibit CD38 and increase NAD+ availability\u003c\/span\u003e\u003cspan\u003e【\u003c\/span\u003e\u003cspan\u003e9\u003c\/span\u003e\u003cspan\u003e】【\u003c\/span\u003e\u003cspan\u003e10\u003c\/span\u003e\u003cspan\u003e】\u003c\/span\u003e\u003cspan\u003e.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli class=\"MsoNormal\"\u003e\n\u003cspan\u003eApigenin also shows neuroprotective effects, supporting healthy brain aging\u003c\/span\u003e\u003cspan\u003e【\u003c\/span\u003e\u003cspan\u003e11\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cdiv class=\"MsoNormal\" align=\"center\"\u003e\u003chr size=\"0\" width=\"100%\" align=\"center\"\u003e\u003c\/div\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cb\u003e\u003cspan\u003eThe Synergy of Science\u003c\/span\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eBy combining these four powerhouse ingredients, \u003cstrong\u003e \u003c\/strong\u003esupports NAD+ production through multiple pathways:\u003c\/span\u003e\u003c\/p\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli class=\"MsoNormal\"\u003e\n\u003cb\u003e\u003cspan\u003eNMN:\u003c\/span\u003e\u003c\/b\u003e\u003cspan\u003e Directly replenishes NAD+ levels.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli class=\"MsoNormal\"\u003e\n\u003cb\u003e\u003cspan\u003eTMG:\u003c\/span\u003e\u003c\/b\u003e\u003cspan\u003e Facilitates Nicotinamide Mononucleotide metabolism via methylation.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli class=\"MsoNormal\"\u003e\n\u003cb\u003e\u003cspan\u003ePterostilbene:\u003c\/span\u003e\u003c\/b\u003e\u003cspan\u003e Protects and enhances NAD+ and Sirtuin\u003cb\u003e \u003c\/b\u003eactivity.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli class=\"MsoNormal\"\u003e\n\u003cb\u003e\u003cspan\u003eApigenin:\u003c\/span\u003e\u003c\/b\u003e\u003cspan\u003e Reduces NAD+ depletion by inhibiting CD38.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cdiv class=\"MsoNormal\" align=\"center\"\u003e\u003chr size=\"0\" width=\"100%\" align=\"center\"\u003e\u003c\/div\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cb\u003e\u003cspan\u003eReferences\u003c\/span\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003col start=\"1\" type=\"1\"\u003e\n\u003cli class=\"MsoNormal\"\u003e\u003cspan\u003eMills, K. F., et al. (2016). Long-term administration of nicotinamide mononucleotide mitigates age-associated physiological decline in mice. \u003ci\u003eCell Metabolism.\u003c\/i\u003e\u003c\/span\u003e\u003c\/li\u003e\n\u003cli class=\"MsoNormal\"\u003e\u003cspan\u003eImai, S., \u0026amp; Guarente, L. (2014). NAD+ and sirtuins in aging and disease. \u003ci\u003eTrends in Cell Biology.\u003c\/i\u003e\u003c\/span\u003e\u003c\/li\u003e\n\u003cli class=\"MsoNormal\"\u003e\u003cspan\u003eCraig, S. A. (2004). Betaine in human nutrition. \u003ci\u003eAmerican Journal of Clinical Nutrition.\u003c\/i\u003e\u003c\/span\u003e\u003c\/li\u003e\n\u003cli class=\"MsoNormal\"\u003e\u003cspan\u003eZhao, X., et al. (2018). TMG alleviates mitochondrial stress by supporting methylation. \u003ci\u003eCell Reports.\u003c\/i\u003e\u003c\/span\u003e\u003c\/li\u003e\n\u003cli class=\"MsoNormal\"\u003e\u003cspan\u003eHoffman, J. R., et al. (2009). Betaine supplementation and exercise performance. \u003ci\u003eJournal of the International Society of Sports Nutrition.\u003c\/i\u003e\u003c\/span\u003e\u003c\/li\u003e\n\u003cli class=\"MsoNormal\"\u003e\u003cspan\u003eRemsberg, C. M., et al. (2008). Pharmacokinetics and metabolism of pterostilbene. \u003ci\u003eLife Sciences.\u003c\/i\u003e\u003c\/span\u003e\u003c\/li\u003e\n\u003cli class=\"MsoNormal\"\u003e\u003cspan\u003eRimando, A. M., et al. (2005). Pterostilbene as an antioxidant. \u003ci\u003eJournal of Agricultural and Food Chemistry.\u003c\/i\u003e\u003c\/span\u003e\u003c\/li\u003e\n\u003cli class=\"MsoNormal\"\u003e\u003cspan\u003eMcCormack, D., \u0026amp; McFadden, D. (2013). Pterostilbene and cancer. \u003ci\u003eAntioxidants \u0026amp; Redox Signaling.\u003c\/i\u003e\u003c\/span\u003e\u003c\/li\u003e\n\u003cli class=\"MsoNormal\"\u003e\u003cspan\u003eChini, C., et al. (2017). CD38 as a regulator of cellular NAD+ homeostasis. \u003ci\u003eNature Metabolism.\u003c\/i\u003e\u003c\/span\u003e\u003c\/li\u003e\n\u003cli class=\"MsoNormal\"\u003e\u003cspan\u003eEscande, C., et al. (2013). Apigenin and CD38 inhibition. \u003ci\u003eJournal of Molecular Biology.\u003c\/i\u003e\u003c\/span\u003e\u003c\/li\u003e\n\u003cli class=\"MsoNormal\"\u003e\u003cspan\u003eNabavi, S. F., et al. (2015). Neuroprotective effects of apigenin. \u003ci\u003eCurrent Neurovascular Research.\u003c\/i\u003e\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cstrong\u003e\u003ci\u003eAdditional Key References on NAD\u003c\/i\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003e\u003ci\u003eSong, Qin et al. “The Safety and Antiaging Effects of Nicotinamide Mononucleotide in Human Clinical Trials: an Update.” Advances in nutrition (Bethesda, Md.) vol. 14,6 (2023): 1416-1435. doi:10.1016\/j.advnut.2023.08.008\u003c\/i\u003e\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003e\u003ci\u003eYi, Lin et al. “The efficacy and safety of β-nicotinamide mononucleotide (NMN) supplementation in healthy middle-aged adults: a randomized, multicenter, double-blind, placebo-controlled, parallel-group, dose-dependent clinical trial.” GeroScience vol. 45,1 (2023): 29-43. doi:10.1007\/s11357-022-00705-1\u003c\/i\u003e\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003e\u003ci\u003eSoma, Mounica, and Satya Kumar Lalam. “The role of nicotinamide mononucleotide (NMN) in anti-aging, longevity, and its potential for treating chronic conditions.” Molecular biology reports vol. 49,10 (2022): 9737-9748. doi:10.1007\/s11033-022-07459-1\u003c\/i\u003e\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003e\u003ci\u003eWei, Zisong et al. “Nicotinamide mononucleotide: An emerging nutraceutical against cardiac aging?.” Current opinion in pharmacology vol. 60 (2021): 291-297. doi:10.1016\/j.coph.2021.08.006\u003c\/i\u003e\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003e\u003ci\u003eRahman, Sajid Ur et al. “Role and Potential Mechanisms of Nicotinamide Mononucleotide in Aging.” Aging and disease vol. 15,2 565-583. 1 Apr. 2024, doi:10.14336\/AD.2023.0519-1\u003c\/i\u003e\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003e\u003ci\u003eFukamizu, Yuichiro et al. “Safety evaluation of β-nicotinamide mononucleotide oral administration in healthy adult men and women.” Scientific reports vol. 12,1 14442. 24 Aug. 2022, doi:10.1038\/s41598-022-18272-y\u003c\/i\u003e\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: rgb(255, 42, 0); font-size: 0.875rem;\"\u003e*This item may take longer to ship out*\u003c\/span\u003e\u003cbr\u003e\u003c\/p\u003e","published_at":"2025-08-18T14:35:41-05:00","created_at":"2025-08-18T14:32:34-05:00","vendor":"Healthgevity","type":"Supplement","tags":["Anti-inflammatory","Detoxification","Immune","Immune Health","Inflammation Support","Neurologic and Cognitive Support"],"price":7999,"price_min":7999,"price_max":7999,"available":true,"price_varies":false,"compare_at_price":null,"compare_at_price_min":0,"compare_at_price_max":0,"compare_at_price_varies":false,"variants":[{"id":46834044600540,"title":"Default Title","option1":"Default Title","option2":null,"option3":null,"sku":null,"requires_shipping":true,"taxable":true,"featured_image":null,"available":true,"name":"NAD SUPPORT+ 60 Caps *","public_title":null,"options":["Default Title"],"price":7999,"weight":170,"compare_at_price":null,"inventory_management":"shopify","barcode":null,"requires_selling_plan":false,"selling_plan_allocations":[],"quantity_rule":{"min":1,"max":null,"increment":1}}],"images":["\/\/shop.connersclinic.com\/cdn\/shop\/files\/nad-support-60-caps-healthgevity-conners-clinic-1186024228.png?v=1755550027","\/\/shop.connersclinic.com\/cdn\/shop\/files\/nad-support-60-caps-healthgevity-conners-clinic-1186024227.png?v=1755550024","\/\/shop.connersclinic.com\/cdn\/shop\/files\/nad-support-60-caps-healthgevity-conners-clinic-1186024226.png?v=1755550021"],"featured_image":"\/\/shop.connersclinic.com\/cdn\/shop\/files\/nad-support-60-caps-healthgevity-conners-clinic-1186024228.png?v=1755550027","options":["Title"],"media":[{"alt":"NAD SUPPORT+ 60 Caps * Healthgevity Supplement - Conners Clinic","id":35420589850844,"position":1,"preview_image":{"aspect_ratio":0.547,"height":1354,"width":740,"src":"\/\/shop.connersclinic.com\/cdn\/shop\/files\/nad-support-60-caps-healthgevity-conners-clinic-1186024228.png?v=1755550027"},"aspect_ratio":0.547,"height":1354,"media_type":"image","src":"\/\/shop.connersclinic.com\/cdn\/shop\/files\/nad-support-60-caps-healthgevity-conners-clinic-1186024228.png?v=1755550027","width":740},{"alt":"NAD SUPPORT+ 60 Caps * Healthgevity Supplement - Conners Clinic","id":35420590506204,"position":2,"preview_image":{"aspect_ratio":1.089,"height":1218,"width":1326,"src":"\/\/shop.connersclinic.com\/cdn\/shop\/files\/nad-support-60-caps-healthgevity-conners-clinic-1186024227.png?v=1755550024"},"aspect_ratio":1.089,"height":1218,"media_type":"image","src":"\/\/shop.connersclinic.com\/cdn\/shop\/files\/nad-support-60-caps-healthgevity-conners-clinic-1186024227.png?v=1755550024","width":1326},{"alt":"NAD SUPPORT+ 60 Caps * Healthgevity Supplement - Conners Clinic","id":35420591128796,"position":3,"preview_image":{"aspect_ratio":1.069,"height":1270,"width":1358,"src":"\/\/shop.connersclinic.com\/cdn\/shop\/files\/nad-support-60-caps-healthgevity-conners-clinic-1186024226.png?v=1755550021"},"aspect_ratio":1.069,"height":1270,"media_type":"image","src":"\/\/shop.connersclinic.com\/cdn\/shop\/files\/nad-support-60-caps-healthgevity-conners-clinic-1186024226.png?v=1755550021","width":1358}],"requires_selling_plan":false,"selling_plan_groups":[],"content":"\u003cp\u003e \u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp class=\"MsoNormal\"\u003eIntroducing a powerful, cutting-edge supplement designed to support and enhance healthy NAD+ levels—vital for energy, cellular repair, and overall vitality. This innovative formula combines NMN (Nicotinamide Mononucleotide), a precursor to NAD+, with TMG(Trimethylglycine), which helps optimize methylation and support detoxification. Added Pterostilbene, a potent antioxidant, helps protect cells from oxidative stress while promoting healthy aging, and Apigenin, a natural flavonoid, further supports cellular health and cognitive function. Together, these ingredients work synergistically to elevate NAD+ levels, boost energy support, improve metabolic function, and promote longevity.\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cb\u003e\u003cspan\u003eNicotinamide Mononucleotide: 1,000mg\u003c\/span\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cb\u003e\u003cspan\u003eKey Benefits:\u003c\/span\u003e\u003c\/b\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli class=\"MsoNormal\"\u003e\n\u003cb\u003e\u003cspan\u003eBoosts NAD+ Levels:\u003c\/span\u003e\u003c\/b\u003e\u003cspan\u003e Nicotinamide Mononucleotide is a direct precursor to NAD+, an essential molecule for energy production and cellular repair. By replenishing NAD+, NMN combats age-related declines in mitochondrial function and supports optimal metabolism.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli class=\"MsoNormal\"\u003e\n\u003cb\u003e\u003cspan\u003eSupports Longevity Pathways:\u003c\/span\u003e\u003c\/b\u003e\u003cspan\u003e Nicotinamide Mononucleotide activates sirtuins, enzymes that regulate DNA repair, inflammation control, and cellular health.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli class=\"MsoNormal\"\u003e\n\u003cb\u003e\u003cspan\u003eEnhances Physical and Cognitive Performance:\u003c\/span\u003e\u003c\/b\u003e\u003cspan\u003e Higher NAD+ levels improve endurance, recovery, and brain function.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cb\u003e\u003cspan\u003eScientific Evidence:\u003c\/span\u003e\u003c\/b\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli class=\"MsoNormal\"\u003e\n\u003cspan\u003eStudies show Nicotinamide Mononucleotide supplementation restores NAD+ levels, improving mitochondrial function and lifespan in animal models\u003c\/span\u003e\u003cspan\u003e【\u003c\/span\u003e\u003cspan\u003e1\u003c\/span\u003e\u003cspan\u003e】\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli class=\"MsoNormal\"\u003e\n\u003cspan\u003eHuman trials demonstrate Nicotinamide Mononucleotide's ability to enhance blood flow and muscle oxygenation\u003c\/span\u003e\u003cspan\u003e【\u003c\/span\u003e\u003cspan\u003e2\u003c\/span\u003e\u003cspan\u003e】\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cdiv class=\"MsoNormal\" align=\"center\"\u003e\u003chr size=\"0\" width=\"100%\" align=\"center\"\u003e\u003c\/div\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cb\u003e\u003cspan\u003eTrimethylglycine (TMG) (as Betaine Anhydrous): 500mg\u003c\/span\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cb\u003e\u003cspan\u003eKey Benefits:\u003c\/span\u003e\u003c\/b\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli class=\"MsoNormal\"\u003e\n\u003cb\u003e\u003cspan\u003eSupports Methylation Processes:\u003c\/span\u003e\u003c\/b\u003e\u003cspan\u003e TMG acts as a methyl donor, critical for processing homocysteine into methionine. This helps maintain healthy DNA and supports NMN's conversion into NAD+.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli class=\"MsoNormal\"\u003e\n\u003cb\u003e\u003cspan\u003eProtects Cells from Stress:\u003c\/span\u003e\u003c\/b\u003e\u003cspan\u003e TMG stabilizes proteins and cell membranes under osmotic stress, ensuring cellular integrity.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli class=\"MsoNormal\"\u003e\n\u003cb\u003e\u003cspan\u003eSupports Heart and Liver Health:\u003c\/span\u003e\u003c\/b\u003e\u003cspan\u003e Helps support homocysteine levels and cardiovascular risk factors.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cb\u003e\u003cspan\u003eScientific Evidence:\u003c\/span\u003e\u003c\/b\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli class=\"MsoNormal\"\u003e\n\u003cspan\u003eResearch highlights TMG’s role in enhancing cellular methylation and metabolic efficiency\u003c\/span\u003e\u003cspan\u003e【\u003c\/span\u003e\u003cspan\u003e3\u003c\/span\u003e\u003cspan\u003e】【4】\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli class=\"MsoNormal\"\u003e\n\u003cspan\u003eTMG improves physical endurance and energy production in athletes\u003c\/span\u003e\u003cspan\u003e【\u003c\/span\u003e\u003cspan\u003e5\u003c\/span\u003e\u003cspan\u003e】\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cdiv class=\"MsoNormal\" align=\"center\"\u003e\u003chr size=\"0\" width=\"100%\" align=\"center\"\u003e\u003c\/div\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cb\u003e\u003cspan\u003ePterostilbene: 50mg \u003c\/span\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cb\u003e\u003cspan\u003eKey Benefits:\u003c\/span\u003e\u003c\/b\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli class=\"MsoNormal\"\u003e\n\u003cb\u003e\u003cspan\u003eAntioxidant Powerhouse:\u003c\/span\u003e\u003c\/b\u003e\u003cspan\u003e A more bioavailable analog of resveratrol, pterostilbene neutralizes free radicals and protects against oxidative damage.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli class=\"MsoNormal\"\u003e\n\u003cb\u003e\u003cspan\u003eActivates Sirtuins:\u003c\/span\u003e\u003c\/b\u003e\u003cspan\u003e Supports longevity by enhancing sirtuin activity, which depends on NAD+.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli class=\"MsoNormal\"\u003e\n\u003cb\u003e\u003cspan\u003eSupports Cognitive Function:\u003c\/span\u003e\u003c\/b\u003e\u003cspan\u003e Protects brain cells from age-related decline, enhancing memory and focus.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cb\u003e\u003cspan\u003eScientific Evidence:\u003c\/span\u003e\u003c\/b\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli class=\"MsoNormal\"\u003e\n\u003cspan\u003eStudies suggest pterostilbene is more bioavailable and effective than resveratrol at promoting cellular health\u003c\/span\u003e\u003cspan\u003e【\u003c\/span\u003e\u003cspan\u003e6\u003c\/span\u003e\u003cspan\u003e】【\u003c\/span\u003e\u003cspan\u003e7\u003c\/span\u003e\u003cspan\u003e】\u003c\/span\u003e\u003cspan\u003e.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli class=\"MsoNormal\"\u003e\n\u003cspan\u003ePterostilbene has anti-inflammatory effects, supporting cardiovascular and brain health\u003c\/span\u003e\u003cspan\u003e【\u003c\/span\u003e\u003cspan\u003e8\u003c\/span\u003e\u003cspan\u003e】\u003c\/span\u003e\u003cspan\u003e.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cdiv class=\"MsoNormal\" align=\"center\"\u003e\u003chr size=\"0\" width=\"100%\" align=\"center\"\u003e\u003c\/div\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cb\u003e\u003cspan\u003eApigenin: 50mg \u003c\/span\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cb\u003e\u003cspan\u003eKey Benefits:\u003c\/span\u003e\u003c\/b\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli class=\"MsoNormal\"\u003e\n\u003cb\u003e\u003cspan\u003eInhibits CD38:\u003c\/span\u003e\u003c\/b\u003e\u003cspan\u003e Apigenin blocks CD38, an enzyme that depletes NAD+ levels, ensuring more NAD+ is available for critical cellular processes.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli class=\"MsoNormal\"\u003e\n\u003cb\u003e\u003cspan\u003eAnti-Inflammatory Properties:\u003c\/span\u003e\u003c\/b\u003e\u003cspan\u003e Supports chronic inflammation, a key driver of aging and age-related diseases.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli class=\"MsoNormal\"\u003e\n\u003cb\u003e\u003cspan\u003eProtects Against Oxidative Stress:\u003c\/span\u003e\u003c\/b\u003e\u003cspan\u003e Enhances cellular resilience by reducing oxidative damage to DNA, proteins, and lipids.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cb\u003e\u003cspan\u003eScientific Evidence:\u003c\/span\u003e\u003c\/b\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli class=\"MsoNormal\"\u003e\n\u003cspan\u003eResearch confirms apigenin’s ability to inhibit CD38 and increase NAD+ availability\u003c\/span\u003e\u003cspan\u003e【\u003c\/span\u003e\u003cspan\u003e9\u003c\/span\u003e\u003cspan\u003e】【\u003c\/span\u003e\u003cspan\u003e10\u003c\/span\u003e\u003cspan\u003e】\u003c\/span\u003e\u003cspan\u003e.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli class=\"MsoNormal\"\u003e\n\u003cspan\u003eApigenin also shows neuroprotective effects, supporting healthy brain aging\u003c\/span\u003e\u003cspan\u003e【\u003c\/span\u003e\u003cspan\u003e11\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cdiv class=\"MsoNormal\" align=\"center\"\u003e\u003chr size=\"0\" width=\"100%\" align=\"center\"\u003e\u003c\/div\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cb\u003e\u003cspan\u003eThe Synergy of Science\u003c\/span\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eBy combining these four powerhouse ingredients, \u003cstrong\u003e \u003c\/strong\u003esupports NAD+ production through multiple pathways:\u003c\/span\u003e\u003c\/p\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli class=\"MsoNormal\"\u003e\n\u003cb\u003e\u003cspan\u003eNMN:\u003c\/span\u003e\u003c\/b\u003e\u003cspan\u003e Directly replenishes NAD+ levels.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli class=\"MsoNormal\"\u003e\n\u003cb\u003e\u003cspan\u003eTMG:\u003c\/span\u003e\u003c\/b\u003e\u003cspan\u003e Facilitates Nicotinamide Mononucleotide metabolism via methylation.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli class=\"MsoNormal\"\u003e\n\u003cb\u003e\u003cspan\u003ePterostilbene:\u003c\/span\u003e\u003c\/b\u003e\u003cspan\u003e Protects and enhances NAD+ and Sirtuin\u003cb\u003e \u003c\/b\u003eactivity.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli class=\"MsoNormal\"\u003e\n\u003cb\u003e\u003cspan\u003eApigenin:\u003c\/span\u003e\u003c\/b\u003e\u003cspan\u003e Reduces NAD+ depletion by inhibiting CD38.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cdiv class=\"MsoNormal\" align=\"center\"\u003e\u003chr size=\"0\" width=\"100%\" align=\"center\"\u003e\u003c\/div\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cb\u003e\u003cspan\u003eReferences\u003c\/span\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003col start=\"1\" type=\"1\"\u003e\n\u003cli class=\"MsoNormal\"\u003e\u003cspan\u003eMills, K. F., et al. (2016). Long-term administration of nicotinamide mononucleotide mitigates age-associated physiological decline in mice. \u003ci\u003eCell Metabolism.\u003c\/i\u003e\u003c\/span\u003e\u003c\/li\u003e\n\u003cli class=\"MsoNormal\"\u003e\u003cspan\u003eImai, S., \u0026amp; Guarente, L. (2014). NAD+ and sirtuins in aging and disease. \u003ci\u003eTrends in Cell Biology.\u003c\/i\u003e\u003c\/span\u003e\u003c\/li\u003e\n\u003cli class=\"MsoNormal\"\u003e\u003cspan\u003eCraig, S. A. (2004). Betaine in human nutrition. \u003ci\u003eAmerican Journal of Clinical Nutrition.\u003c\/i\u003e\u003c\/span\u003e\u003c\/li\u003e\n\u003cli class=\"MsoNormal\"\u003e\u003cspan\u003eZhao, X., et al. (2018). TMG alleviates mitochondrial stress by supporting methylation. \u003ci\u003eCell Reports.\u003c\/i\u003e\u003c\/span\u003e\u003c\/li\u003e\n\u003cli class=\"MsoNormal\"\u003e\u003cspan\u003eHoffman, J. R., et al. (2009). Betaine supplementation and exercise performance. \u003ci\u003eJournal of the International Society of Sports Nutrition.\u003c\/i\u003e\u003c\/span\u003e\u003c\/li\u003e\n\u003cli class=\"MsoNormal\"\u003e\u003cspan\u003eRemsberg, C. M., et al. (2008). Pharmacokinetics and metabolism of pterostilbene. \u003ci\u003eLife Sciences.\u003c\/i\u003e\u003c\/span\u003e\u003c\/li\u003e\n\u003cli class=\"MsoNormal\"\u003e\u003cspan\u003eRimando, A. M., et al. (2005). Pterostilbene as an antioxidant. \u003ci\u003eJournal of Agricultural and Food Chemistry.\u003c\/i\u003e\u003c\/span\u003e\u003c\/li\u003e\n\u003cli class=\"MsoNormal\"\u003e\u003cspan\u003eMcCormack, D., \u0026amp; McFadden, D. (2013). Pterostilbene and cancer. \u003ci\u003eAntioxidants \u0026amp; Redox Signaling.\u003c\/i\u003e\u003c\/span\u003e\u003c\/li\u003e\n\u003cli class=\"MsoNormal\"\u003e\u003cspan\u003eChini, C., et al. (2017). CD38 as a regulator of cellular NAD+ homeostasis. \u003ci\u003eNature Metabolism.\u003c\/i\u003e\u003c\/span\u003e\u003c\/li\u003e\n\u003cli class=\"MsoNormal\"\u003e\u003cspan\u003eEscande, C., et al. (2013). Apigenin and CD38 inhibition. \u003ci\u003eJournal of Molecular Biology.\u003c\/i\u003e\u003c\/span\u003e\u003c\/li\u003e\n\u003cli class=\"MsoNormal\"\u003e\u003cspan\u003eNabavi, S. F., et al. (2015). Neuroprotective effects of apigenin. \u003ci\u003eCurrent Neurovascular Research.\u003c\/i\u003e\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e\u003cstrong\u003e\u003ci\u003eAdditional Key References on NAD\u003c\/i\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003e\u003ci\u003eSong, Qin et al. “The Safety and Antiaging Effects of Nicotinamide Mononucleotide in Human Clinical Trials: an Update.” Advances in nutrition (Bethesda, Md.) vol. 14,6 (2023): 1416-1435. doi:10.1016\/j.advnut.2023.08.008\u003c\/i\u003e\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003e\u003ci\u003eYi, Lin et al. “The efficacy and safety of β-nicotinamide mononucleotide (NMN) supplementation in healthy middle-aged adults: a randomized, multicenter, double-blind, placebo-controlled, parallel-group, dose-dependent clinical trial.” GeroScience vol. 45,1 (2023): 29-43. doi:10.1007\/s11357-022-00705-1\u003c\/i\u003e\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003e\u003ci\u003eSoma, Mounica, and Satya Kumar Lalam. “The role of nicotinamide mononucleotide (NMN) in anti-aging, longevity, and its potential for treating chronic conditions.” Molecular biology reports vol. 49,10 (2022): 9737-9748. doi:10.1007\/s11033-022-07459-1\u003c\/i\u003e\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003e\u003ci\u003eWei, Zisong et al. “Nicotinamide mononucleotide: An emerging nutraceutical against cardiac aging?.” Current opinion in pharmacology vol. 60 (2021): 291-297. doi:10.1016\/j.coph.2021.08.006\u003c\/i\u003e\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003e\u003ci\u003eRahman, Sajid Ur et al. “Role and Potential Mechanisms of Nicotinamide Mononucleotide in Aging.” Aging and disease vol. 15,2 565-583. 1 Apr. 2024, doi:10.14336\/AD.2023.0519-1\u003c\/i\u003e\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003e\u003ci\u003eFukamizu, Yuichiro et al. “Safety evaluation of β-nicotinamide mononucleotide oral administration in healthy adult men and women.” Scientific reports vol. 12,1 14442. 24 Aug. 2022, doi:10.1038\/s41598-022-18272-y\u003c\/i\u003e\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: rgb(255, 42, 0); font-size: 0.875rem;\"\u003e*This item may take longer to ship out*\u003c\/span\u003e\u003cbr\u003e\u003c\/p\u003e"}