Lab - Genova - Fat Soluble Vitamin Assay

The Fat-Soluble Vitamins Profile is a great tool to gain an overall perspective of a patient's health, nutrient processing, and dietary insufficiencies. Serum levels of the fat-soluble vitamins A, D, E, K plus beta-carotene and coenzyme Q10 are measured to evaluate total body status of these antioxidant nutrients.

What are the benefits of measuring all fat-soluble vitamins together?

Testing these nutrients together in one panel is important because nutrient functionality is dependent on the adequate supply of each nutrient. For bone health, taking vitamin D without adequate levels of vitamins A, E, and K may be detrimental since all are needed for proper bone calcification. Antioxidants, such as vitamin E, CoQ10, and beta-carotene, help ensure proper oxidation-reduction chain reactions.

Vitamins measured include:

• Vitamin A specific maintenance roles have been reported for vision, bone growth, skin and mucosal integrity, spermatogenesis, as well as protection against cataracts, atherosclerosis, macular degeneration and cancer.
• Vitamin D, "the sunshine vitamin", is necessary for maintaining blood levels of calcium and phosphorus for healthy teeth and bones. Vitamin D also plays a vital role in immune functions and is essential for health maintenance.
• Vitamin E is an important free radical scavenger and protective antioxidant for membrane tissues, helping to stop damage to healthy cells. Both gamma and alpha tocopherol are reported to better assess oxidative stress and inflammation.
• Vitamin K1 and K2 is important in the deposition of ionic calcium needed for proper blood coagulation (K1) and bone formation(K2). Research finds vitamin K to be a potential protector against osteoporosis, atherosclerosis, and possibly cancer (K2).
• Beta-carotene serves as an important antioxidant in keeping cells healthy, and also serving as a pool that is converted to vitamin A when needed. Beta-carotene also helps to identify a healthy diet.
• Coenzyme Q10 (CoQ10) allows food energy to be converted into cellular energy. Organs with the highest need for energy, such as the heart, lungs, and liver, require high levels of CoQ10. CoQ10 also protects cells from free radicals, helps with proper mitochondrial function, and is associated with cardiovascular health.

The Fat-Soluble Vitamins Profile tests for levels of:

• Vitamin A
• Vitamin D
• Vitamin E
• Vitamin K
• Beta-Carotene
• Coenzyme Q10

Assessing fat-soluble vitamin levels is essential in patients with the following conditions:

• Impaired immune function
• Reoccuring infections
• Neurological disease
• Impaired digestion and absorption
• Heart disease
• Osteopenia and Osteoporosis
• Chronic fatigue
• Increased oxidative stress
• Poor dietary intake

Test name(s): 0036 - Fat-Soluble Vitamins Profile - Serum

Method: UPLC; EIA; Chemiluminescence

*Not reported in New York