Lab- Cyrex Array 14- Mucosal Immune Reactivity Screen - Conners Clinic
Lab- Cyrex Array 14- Mucosal Immune Reactivity Screen - Conners Clinic
Lab- Cyrex Array 14- Mucosal Immune Reactivity Screen - Conners Clinic
Lab- Cyrex Array 14- Mucosal Immune Reactivity Screen - Conners Clinic

Lab- Cyrex Array 14- Mucosal Immune Reactivity Screen

Vendor
Conners Clinic
Regular price
$439.00
Sale price
$439.00
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This Array is a very cost effective, easy, and non-invasive method, to measure mucosal immune reactivity to a range of exogenous and endogenous antigens. The categories of antigens include assessments for intestinal dysfunction, food immune reactivity, gut dysbiosis, infection, and possible enteric nervous system autoimmune reactivity. This mucosal immune response is the body’s first immune system reaction. If steps to bring balance back to the mucosal immune response are not taken, the immune reactivity may result in a breach of the intestinal barrier, followed by a systemic immune reaction. The inflammation of systemic autoantibodies contributes to the progression of autoimmune and neuroautoimmune reactivities.

Mucosal screening with Array 14 has the following advantages:

  • Non-invasive specimen collection

  • Assesses the unique mucosal reactions to an array of gut-related environmental antigens

  • Identifies an early event in immune reactivity to an array of gut-related environmental antigens

  • Measures immune reactivity at its earliest stage for potential Celiac disease, non-celiac gluten-

    sensitivity, irritable bowel disease, etc.

  • Identify gut dysbiosis

  • Monitor effectiveness of dietary protocols and other interventions

  • Cost effectively assess multiple antigens at once

Since the mucosal immune system is a central component of host defense, as a whole, any dysregulation and inflammatory reaction in the GI tissue may result in intestinal barrier dysfunction and the entry of digested, or undigested, dietary proteins into the circulation. Dietary proteins in the circulation result in systemic immune response and the production of very high levels of IgG and IgA against dietary proteins and peptides.

This breach of the intestinal barrier by dietary proteins, and other molecules, due to loss of tolerance not only can lead to IgG and IgA production in blood, but also might lead to an immune response to different target organs and the induction of autoimmune diseases.29 44 45 46 47 48 49

Environmental triggers may have the capacity to affect the tight junctions. Such triggers may include bacterial antigens, viral antigens, mold antigens, xenobiotics, dietary components, and associated tissue antigens. The antibodies can react with their specific antigens and form immune complexes, which further contribute to the entry of antigens, immune complexes, or other inflammatory molecules into the submucosa, and then into circulation. Due to structural similarity between the intestinal barrier and blood- brain barrier (BBB), these IgA + IgM antibodies, immune complexes and inflammatory signals can also affect the integrity of the BBB resulting in autoimmunity against nervous system tissues.