A common challenge that people face is dealing with chronic infections and autoimmune disorders. Often, sub-clinical bacterial, viral, fungal, and tick-born illness can be masked and difficult to discover and address. The chronicity of such conditions can lead to the formation of self-antibodies, often worsening the morbidity. If one you effectively aid the body in killing the active antigen, you may be able to ward off the B-cell production of antibodies and lower the risk of an autoimmune event.

LX Chronic has been specially designed for those with chronic, stubborn, and often hidden infections. Artemisia is an excellent fighter of intracellular bacteria as it readily absorbs and passes through cell membranes. Coriolus is one of the best sources of polysaccharides that help stimulate Macrophage attack on co-infections and Monolaurin is a proven, broad-spectrum killer of both gram-positive and gram-negative bacteria. The unique addition of thymus gland tissue gently supports your own production of immune cells. The Sodium Alginate serves as an excellent chelator of lipopolysaccharides, the byproducts of killing bacteria and the unique enzyme blend helps breakdown the bacteria’s protective biofilm. LX Chronic would also be a great supplement for other chronic viral, mold and fungal infections.

Ingredients

Artemisia annua (sweet wormwood): Artemisinin, extracted from the medicinal plant Artemisia sp. is an effective anti-malarial drug. In 2015, elucidation of the effectiveness of artemisinin as a potent anti-malarial drug was even acknowledged with a Nobel prize. (1) Recently, it has also been investigated for their antineoplasia properties, with interesting and promising results. (2) Artemisia annua also supports various condi- tions such as diabetes, heart diseases, arthritis and eczema and possess- es various effects such as antibacterial, antioxidant, anticoccidial, and antiviral effects. (3)

Thymus tissue: Thymus tissue concentrate derived from pure, lyophilized tissue concentrates from New Zealand, which is considered the cleanest and most environmentally responsible country to source from on the planet.

Sodium Alginate (Grifola frondosa and Ganoderma lucidum): Sodium alginate is a soluble dietary fiber extracted from brown seaweed and its solution has been used to support GUT healing, bind toxins in the intestinal tract, and as a hemostatic agent to support gastrointestinal bleeding due to gastric ulcers. (4, 5)

Turkey-tail Mushroom extract (Coriolus Versicolor): The polysaccharo-peptide (PSP) isolated from the Coriolus versicolor (Yun zhi) has its effects on various immune subsets, and the positive clinical data has led to its widespread adoption as an adjunct in neoplasias and immune therapies. Ancient Chinese formulations of CV have long been believed to generally promote health, strength, and longevity. Laboratory studies suggest it may have antimicrobial, antiviral, and anti-tumor properties. (6, 7)

Monolaurin (monolaurate): Monolaurin is a natural compound found in coconut oil and is known for its protective biological activities as an antimicrobial agent. It has also been shown to have antifungal activity against a variety of biofilms as measured by decreased numbers of viable biofilm-associated bacteria as well as decreased biofilm biomass. (8, 9)

Enzyme blend (Glucoamylase, Chitosanase, Cellulase, Hemicellulase, Pectinase, Beta-Glucanase): Our unique enzyme formula supports normal gastrointestinal function and microbiota by assisting degradation of biofilm of bacteria and yeast common with chronic infections. It has been shown that enzymes act synergistically, as demonstrated by crystal violet staining of static biofilms, significantly reducing viable cell counts compared to individual enzyme treatment in the dynamic model. (10) The biofilm matrix is the glue that holds cells together and can be key to protect invading species and up to 80% of human bacterial infections are biofilm associated. (11, 12)

Directions

Take 2 capsules daily, preferably 30 minutes away from food, or as recommended by your Health Care Professional.

References

1. Kiani BH, Suberu J, Mirza B. Cellular engineering of Artemisia annua and Artemisia dubia with the rol ABC genes for enhanced production of potent anti-malari- al drug artemisinin. Malar J. 2016;15(1):252. Published 2016 May 4. doi:10.1186/s12936-016-1312-8

2. Isani G, Bertocchi M, Andreani G, et al. Cytotoxic Effects of Artemisia annua L. and Pure Artemisinin on the D-17 Canine Osteosarcoma Cell Line. Oxid Med Cell Longev. 2019;2019:1615758. Published 2019 Jul 4. doi:10.1155/2019/1615758

3. Alesaeidi S, Miraj S. A Systematic Review of Anti-malarial Properties, Immunosuppressive Properties, Anti-inflammatory Properties, and Anti-cancer Properties of Artemisia Annua. Electron Physician. 2016;8(10):3150–3155. Published 2016 Oct 25. doi:10.19082/3150

4. Horibe S, Tanahashi T, Kawauchi S, Mizuno S, Rikitake Y. Preventative Effects of Sodium Alginate on Indomethacin-induced Small-intestinal Injury in Mice. Int J Med Sci. 2016;13(9):653–663. Published 2016 Aug 1. doi:10.7150/ijms.16232

5. Mackie AR, Macierzanka A, Aarak K, et al. Sodium alginate decreases the permeability of intestinal mucus. Food Hydrocoll. 2016;52:749–755. doi:10.1016/j.food- hyd.2015.08.004

6. Saleh MH, Rashedi I, Keating A. Immunomodulatory Properties of Coriolus versicolor: The Role of Polysaccharopeptide. Front Immunol. 2017;8:1087. Published 2017 Sep 6. doi:10.3389/fimmu.2017.01087

7. Friedman M. Mushroom Polysaccharides: Chemistry and Antiobesity, Antidiabetes, Anticancer, and Antibiotic Properties in Cells, Rodents, and Humans. Foods. 2016;5(4):80. Published 2016 Nov 29. doi:10.3390/foods5040080

8. Seleem D, Chen E, Benso B, Pardi V, Murata RM. In vitro evaluation of antifungal activity of monolaurin against Candida albicans biofilms. PeerJ. 2016;4:e2148. Published 2016 Jun 22. doi:10.7717/peerj.2148

9. Hess DJ, Henry-Stanley MJ, Wells CL. The Natural Surfactant Glycerol Monolaurate Significantly Reduces Development of Staphylococcus aureus and Enterococ- cus faecalis Biofilms. Surg Infect (Larchmt). 2015;16(5):538–542. doi:10.1089/sur.2014.162

10. Olsen NMC, Thiran E, Hasler T, et al. Synergistic Removal of Static and Dynamic Staphylococcus aureus Biofilms by Combined Treatment with a Bacteriophage Endolysin and a Polysaccharide Depolymerase. Viruses. 2018;10(8):438. Published 2018 Aug 18. doi:10.3390/v10080438

11. Visick KL, Schembri MA, Yildiz F, Ghigo JM. Biofilms 2015: Multidisciplinary Approaches Shed Light into Microbial Life on Surfaces. J Bacteriol. 2016;198(19):2553–2563. Published 2016 Sep 9. doi:10.1128/JB.00156-16

12. Biofilm infections, their resilience to therapy and innovative treatment strategies. J Intern Med. 2012 Dec;272(6):541-61. doi: 10.1111/joim.12004. Epub 2012 Oct 29.

13. Song M, Zeng Q, Xiang Y, et al. The antibacterial effect of topical ozone on the treatment of MRSA skin infection. Mol Med Rep. 2018;17(2):2449–2455. doi:10.3892/mmr.2017.8148

14. Gupta G, Mansi B. Ozone therapy in periodontics. J Med Life. 2012;5(1):59–67.