ortho-molecular

  OVERVIEW In the US, eye health is a major concern for those over 60 years of age. The eye is the most susceptible organ to oxidative damage caused by light, toxins (smoke), atmospheric oxygen and abrasion. As ultraviolet and blue light pass through the retina to the photoreceptors (rods and cones) and the pigmented epithelial (PE) cells, reactive oxygen species (free radicals) are generated. If there are insufficient antioxidants available to neutralize free radicals, the eye undergoes excessive oxidative damage. 4Sight was formulated with a specific blend of botanicals, nutrients, antioxidants and minerals, shown in research to support healthy eye function. The formula provides antioxidant support as well as key nutrients to care for and maintain the long-term health of the eyes. Suggested Use: 2 capsules per day or as recommended by your health care professional. INGREDIENT BENEFITS Alpha Lipoic Acid Alpha lipoic acid (ALA) is a potent, versatile antioxidant that is both water- and fat-soluble. ALA has been shown to inhibit aldose reductase, which prevents sorbitol-induced leakage of important antioxidants from eye tissues and recharges ALA vitamin C, E and glutathione. Ginkgo Biloba Ginkgo biloba has been shown to provide key antioxidant support for eyes. Carotenoids: Lutein, Zeaxanthin, Lycopene Lutein and zeaxanthin are carotenoid pigments whose role in eye health is well-established from epidemiological, clinical and interventional studies. Zinc A vital coenzyme for eye tissue, zinc is a necessary component in antioxidant enzymes including superoxide dismutase, glutathione peroxidase and catalase. Bilberry Bilberry extract contains a high amount of the antioxidants known as anthocyanidins, similar to those found in grape seeds. Bilberry has a long history of use in eye health. Quercetin A flavonoid found in a variety of herbs, vegetables and fruits, quercetin provides antioxidant support for eyes. Taurine Taurine concentration is high in the retina and is required for retinal tissue growth.

Bergamot Bioactive Polyphenolic Fractions (BPF) contains a powerful and unique array of cholesterol-balancing and cardio-protective polyphenolic flavonoids. Emerging clinical research has demonstrated that BPF help maintain healthy total cholesterol (TC), high density lipoprotein (HDL), low density lipoprotein (LDL), very low density lipoprotein (VLDL) and triglyceride (TRI) levels. Research has also demonstrated that BPF provides antioxidant-balancing properties and maintains normal inflammatory balance to help preserve coronary arteries. Overview Optimizing cardiovascular health is a leading concern for many adults, and maintaining balanced cholesterol levels are an important part of that process. Though cholesterol can be consumed through food, circulating cholesterol levels are primarily produced and controlled by the liver using the rate control enzyme, HMG-CoA reductase (HMGCR). Because of its pronounced role in cholesterol synthesis, inhibiting HMGCR has become a primary target of many traditional therapies. Numerous clinical trials have shown the specific BPF found in Bergamot BPF works at the level of the liver to help maintain and support healthy cholesterol levels and preserve coronary arteries by maintaining normal inflammatory balance. What are Bergamot Polyphenolic Fractions? Bergamot (Citrus bergamia) is a citrus plant that grows almost exclusively in the narrow coastal Calabria region in southern Italy. The local population quickly discovered bergamot juice could be used to help support healthy cholesterol levels and optimize cardiovascular wellness. Bergamot’s health benefits derive from its unique profile of phenolic compounds such as, neoeriocitrin, neohesperidin, naringin, rutin, neodesmin, rhoifolin and poncirin. Naringin has been shown to be beneficial in maintaining normal inflammatory balance, while neoeriocitrin and rutin have been found to exhibit a strong capacity to quench free radicals and maintain healthy LDL cholesterol levels. Also, bergamot is rich in brutieridine and melitidine, which have a unique ability to dampen HMG-CoA reductase. Using a patented extraction technology through collaborative works of various universities and research institutions, Bergamot BPF contains Bergamonte®, the highest concentration available of these potent phenolic compounds. Cholesterol-Balancing Properties In a placebo-controlled, clinical trial consisting of 77 patients divided into four treatment groups, 1,000 mg of BPF helped maintain healthy levels of all blood lipid markers (HDL, LDL, TC, TRI).1 Also, this same clinical trial showed that BPF activated the inflammatory-balancing enzyme AKT and reduced malondialdehyde production in neutrophils.1 Another clinical trial conducted on 80 patients over six months showed 1,500 mg of BPF maintained normal levels of small density LDL and supported normal carotid IMT thickness.2 In a placebo- controlled study involving 238 patients, 1,000 mg of BPF maintained healthy cholesterol levels and outperformed the group receiving the traditional therapy. Following a 60-day wash out phase in patients who had been on traditional therapies, 1,500 mg of BPF maintained normal LDL levels and optimized several other parameters of cardiovascular health.3 Several other recently published placebo-controlled clinical trials have also documented that BPF can help maintain normal inflammatory balance, antioxidant potential, healthy cholesterol levels, and CoQ-10 levels in humans.  

Vitamin C is a water-soluble vitamin most widely known for its role in supporting immune health. It provides potent antioxidant protection, as it helps combat cellular damage from free radicals caused by oxidative stress, thus protecting health overall. Vitamin C also boosts the function of immune cells and is a key nutrient in the synthesis of collagen. Buffered C Powder is balanced with calcium, magnesium and potassium to gently deliver high-concentration vitamin C to reduce the potential of gastrointestinal upset.

CLINICAL APPLICATIONS Designed to Support Mood and Brighten Mental Outlook Supports the Production of the Neurotransmitters Serotonin, GABA, Dopamine, Norepinephrine and Epinephrine Supports Calming Alpha Brain Wave Activity Addresses Neurotransmitter Signaling Systems OVERVIEW Neurotransmitters are the chemical messengers that regulate mood, memory, the sleep cycle and daily stress. Adequate neurotransmitter production depends on an adequate supply of amino acids, vitamins and minerals in the diet. High levels of stress, dietary deficiencies, genetics, medications and toxins all play a role in neurotransmitter depletion. CereVive provides the nutrients required to help optimize neurotransmitter production. CereVive is formulated to support a positive mental outlook and a relaxed, focused state. It includes amino acid precursors and bioactive nutrients that support healthy levels of neurotransmitters such as gamma-aminobutyric acid (GABA), serotonin, dopamine, norepinephrine and epinephrine. Maintaining adequate neurotransmitter production is vital for regulating mood, appetite, memory, focus, energy levels and a healthy sleep cycle. Suggested Use: 4 capsules one to two times per day on an empty stomach or as recommended by your health care professional. INGREDIENTS L-Theanine L-theanine is an amino acid found abundantly in green tea. L-theanine has been shown to quickly improve stress perception and resilience. The stress-buffering mechanisms of L-theanine have been connected to its ability to increase serotonin and dopamine production in the brain. L-theanine has also been shown to significantly increase alpha brain wave activity, which is critical for increasing attention as well as promoting a sense of relaxation.  PharmaGABA® Gamma-amino butyric acid (GABA) is one of the major inhibitory neurotransmitters in the brain. GABA provides a calming effect and is a primary component of the body’s stress fighting mechanisms. Inositol Inositol is a B vitamin that is an important component of cell membrane signaling. As part of the cellular signaling system of the CNS, inositol is crucial for the release of neurotransmitters from within the nerve cells. A deficiency of inositol can affect brain signaling, resulting in inadequate neurotransmitter release causing irritability, worry and restlessness. 5-HTP 5-hydroxytryptophan (5-HTP) is an amino acid intermediate that is directly converted into the mood-regulating neurotransmitter, serotonin. Maintaining a healthy serotonin level is important regulating appetite and sleep cycle and for supporting a sense of calmness. L-Tyrosine L-tyrosine is an amino acid precursor to the neurotransmitters dopamine, norepinephrine and epinephrine. These neurotransmitters help regulate mood, memory and concentration. L-tyrosine is able to cross the blood-brain barrier by the large neutral amino acid (LNAA) carrier system that is present in brain capillaries. Mucuna pruriens Mucuna pruriens, commonly known as Velvet bean, includes standardized doses of L-dopa. L-dopa is the direct precursor to the neurotransmitter dopamine, which helps maintain a positive mental outlook, and motivation. It is also important for supporting cognitive function. Micronutrients CereVive includes several nutrients that are required in synthesis pathways for the neurotransmitters serotonin, GABA, dopamine, norepinephrine and epinephrine. This includes 5-methyltetrahydrofolate (5-MTHF), vitamin B6, vitamin C, zinc and magnesium. 5-MTHF is the biologically active form of the B vitamin folic acid, which is vital to supporting proper mood regulation. 5-MTHF works together with B12 as methyl group donor. Methyl (CH3) group donation is important for maintaining neurotransmitter synthesis. Magnesium is a mineral that calms the nervous system by binding to glutamate receptors, which reduces excitatory neurotransmitter activity.

NOTE: If this product is on Backorder, consider Whole Body Collagen Powder CLINICAL APPLICATIONS Protects and Promotes Connective Tissue Biosynthesis Supports the Body’s Processes of Cartilage, Tendon, Ligament and Fascia Self-Repair Supports Joint Lubrication, Joint Cushioning, and Normal Connective Tissue Inflammatory Response Supports Normal Rejuvenation of Healthy Hair, Skin and Nails OVERVIEW Over time lifestyle factors can cause reduced elasticity in cartilage, tendons, ligaments and skin. This not only leads to wrinkles and decreased dermal matrix, but to soft tissue and joint discomfort. FORTIGEL® has been shown in human studies to stimulate collagen regeneration, type II collagen and aggrecan, which all help to maintain healthy connective tissue. Most therapies simply block joint pain and connective tissue discomfort, and in doing so inhibit the regeneration and elongation of specific precursors, such as polysaccharides, and deplete nutrients such as vitamin C and magnesium that maintain joint and connective tissue health. FORTIGEL®, TendoActive® and Mobilee® protect and preserve cartilage, tendons, ligaments, intervertebral discs, and fascia. These patented ingredients support the natural healing process and maintain the structure of connective tissues. Suggested Use: 1 scoop (7.6 grams) in 8 oz of water or the beverage of your choice per day or as recommended b your health care professional. Can also be added to food and baking products. INGREDIENT BENEFITS Collagen Hydrolysate as FORTIGEL®, is backed by more than fifteen studies, provides bioactive collagen peptides (BCPs), which contain high concentrations of specific peptides that comprise connective tissue. The precise length of the short-chain peptides and their low average molecular weight allows easy absorption, transport, and accumulation to target connective tissue. FORTIGEL® provides 5 g hypoallergenic protein per serving from a sustainable protein source without the risk of oxalate kidney stones from higher-dose collagen products. Clinical studies on FORTIGEL® demonstrate joint and tendon health benefits. Hyaluronic Acid Extract as Mobilee®, is a patented rooster comb extract rich in high molecular weight hyaluronic acid (HA), which is responsible for the viscoelastic, lubricating properties of synovial fluid. This extract also contains collagen and other glycosaminoglycans (GAGs). Hyaluronic acid also plays a role in the biophysical, biochemical and cell regulation processes in joint synovial tissues. Scientific evidence shows Mobilee® supports chrondrocytes and synovial cell function, and is two to four times more active than regular HA in supporting synovial fluid health. The latest clinical research includes HA in proactive and maintenance approaches to joint care and supports normal range-of-motion. Research suggests Mobilee® supports the quality of synovial fluid by positively influencing synovial HA concentration, and by reducing the expression of degradative factors in synovial fluid. Type I Collagen and Mucopolysaccharides as TendoActive®, is a combination of type I collagen and mucopolysaccharides. Adult tendons, ligaments and fascial tissue are comprised mainly of type I collagen molecules organized into structural units. The molecular structure and organization of tendon, ligament and fascial collagen fibrils are key determinants in the ability of these tissues to endure mechanical force and fuel self-repair. While collagen provides much of tendon/ligament structure and strength, mucopolysaccharides are the “glue” that holds them together and allows them to stretch, flex, bend and maintain their resilience. Mucopolysaccharides are a critical component of extracellular matrix and are important in maintaining structural integrity, lubrication and spacing of collagen fibers. Furthermore, mucopolysaccharides have been shown to increase collagen and non-collagenous protein synthesis in cultures of bovine tenocytes and ligament cells. TendActive® has been shown to be efficacious in medial and lateral epicondyle tendon patients, Achilles tendon patients and plantar fascia patients. Cofactor support for optimal connective tissue support and collagen production is provided by vitamin C and magnesium in the highest bioavailable form as Albion TRAACS® Magnesium Bisglycinate Chelate. Vitamin C not only protects connective tissue from free radical damage, but is critical for peptide folding and tri-helical peptide pro-collagen fiber formation before they are exported from the cytoplasm for final fiber trimming. Magnesium also plays a critical role as a cofactor for every enzyme involved in collagen formation, as well as balancing MMP and TIMP enzyme activity for optimal degradation and formation. *This product may take longer to ship out*

OVERVIEW CoQ-10 is a lipid-soluble antioxidant found in every cell in the body. CoQ-10 is abundant in the mitochondrial membrane and plays an important role in the synthesis of adenosine triphosphate (ATP), a molecule of chemical energy upon which all cellular functions depend. This CoQ-10 300 mg formulation is delivered in an oil-based proprietary form and includes natural vitamin E for enhanced absorption and maximum stability. Suggested Use: 1 soft gel capsule per day or as recommended by your health care professional INGREDIENT BENEFITS CoQ-10 Depletion The body’s ability to produce and metabolize CoQ-10 has been reported to decrease with age. CoQ-10 deficiency may be caused by insufficient dietary intake of CoQ-10, impairment in CoQ-10 production, drug-induced CoQ10 depletion, gene mutations and oxidative stress. HMG-CoA reductase is an enzyme required for the synthesis of cholesterol and CoQ-10. Cholesterol lowering medications inhibit this enzyme in order to reduce cholesterol synthesis, but may also simultaneously deplete CoQ-10 status. Cardiovascular Health CoQ-10 is important for all energy-dependent processes, and is especially helpful in strengthening contraction of the heart muscle. CoQ-10 is also important for protection against free radical damage to the arterial vessels. Blood Sugar Balance The electron transport chain, a biochemical pathway in which CoQ-10 plays a major role, significantly impacts carbohydrate metabolism. CoQ-10 has been shown to support healthy blood sugar metabolism.

Clinical Applications Supports Healthy Digestion and Maximizes Nutrient Absorption Targeted Enzyme Support for Food Sensitivities Designed to Enhance the Benefits of a Plant-Rich Diet Stimulates the Release and Production of Natural DigestiveEnzymes in the Pancreas Supports Gastric Acid Balance and Digestive Function Because of our hectic lifestyle, and the way we often consume food that is frequently overcooked, digestion can often be less than optimal. A thorough digestion of foodstuffs with enzymes prevents foods from being fermented in the gut and the proliferation of “bad” bacteria and yeast at the expense of “good” intestinal bacteria. Another benefit of enzymes is that more nutrition can be derived from food. In addition, regular bowel movements result from this better digestion. Digestzyme-V is specifically designed to support digestion and help unlock more nutrition from food. Digestzyme-V is a comprehensive blend of acid-resistant, plant-based enzymes designed to help maximize the digestion and absorption of nutrients from food. Each capsule includes lipase, amylase, lactase, CereCalase® and protease to aid in the digestion of protein, fat, starches, fiber and other difficult to digest foods known to cause food sensitivities. CereCalase®, a special blend of hemicellulase, beta-glucanase and phytase, is specially formulated to digest the cell walls of plants, providing better nutrition from a plant-based diet. Digestzyme-V also includes Gentian root, a traditional bitter herb, and artichoke, a natural choleretic, added to stimulate the body’s natural production of enzymes and bile. Suggested Use: 1-2 capsules 15 minutes before a meal or as recommended by your health care professional

CLINICAL APPLICATIONS Supports Cardiovascular and Neurologic Health Supports Homocysteine Balance Supports Healthy Arterial Function Maintains Normal Inflammatory Balance OVERVIEW For some women, the accompanying signs and effects that can occur during the transition years can be strong enough to significantly disrupt daily activities and sense of well-being. Femarin contains five key ingredients that provide proven phytoestrogen shown to support a woman’s unique needs during this period. Specifically, Femarin’s formula addresses hormonal balance, maintains normal inflammatory balance and provides antioxidant support, as well as cardiovascular and bone support for a full spectrum of protection and menopausal symptom relief. Suggested Use: 2 capsules per day in divided doses or as recommended by your health care professional. INGREDIENT BENEFITS Black Cohosh Root Extract Black cohosh root extract has been extensively studied for its hormone balancing benefits during peri-menopause and menopause. Trans-Resveratrol Resveratrol, a polyphenol found in grapes and red wine, has been shown to have an effect on free radical scavenging and antioxidant properties in various tissues. Trans-resveratrol provides a range of supportive activities including hormonal balance and maintaining normal inflammatory balance. Licorice Root Extract Licorice root is a botanical used medicinally in both Western and Eastern cultures for several thousands of years, and is widely used today in Chinese medicine. The active components of licorice root include glycyrrhizin and isoflavones. Licorice root’s isoflavones have been shown to exert a balancing effect on estrogen levels. Gamma Oryzanol Gamma oryzanol (ferulic acid) is a natural compound extracted from rice bran oil. Gamma oryzanol was first shown to be effective for relieving hot flashes in the early 1960s. Numerous studies have highlighted the benefits of gamma oryzanol for menopausal complaints. Dong Quai Considered by many as the woman’s herb, Dong quai (Angelica sinensis) is native to China and Korea, where it is considered as a “female ginseng” due to its ability to reduce painful menstruation, support a regular and healthy menstrual cycle, and reduce menopausal symptoms, including hot flashes.

Dr. Conners' Note: We've found a BETTER product: PharmaGABA from DFH is a better product.  *This item may take longer to ship*

CLINICAL APPLICATIONS Provides Protection for Neurons from Free Radical Damage Enhances Cerebral Blood Flow and Cognitive Health Provides Targeted Antioxidant Support for the Brain OVERVIEW Maintaining cognitive function is an increasingly important challenge with the aging United States population. Aging is often associated with functional changes in the brain that can affect event recall ability, thought organization, and ability for self-expression. While some memory loss is common in the aging population, factors such as free-radical damage, nutrient deficiencies, lifestyle choices and emotional stress are known to affect cognition with age. The brain is part of the nervous system, which is made up of neurons responsible for processing and transmitting information using neurotransmitters and electrical ion channels. Maintaining the function of various aspects of neuron communication is integral to maintaining optimal cognitive function.  Membrin provides vinpocetine and ginkgo biloba to support cerebral blood circulation, decrease excitotoxicity and scavenge damaging free radicals. In addition, vinpocetine has specifically been shown to inhibit phosphodiesterase, and therefore helps increase cerebrvascular blood flow and improve memory. Together with huperzine A, a potent acetylcholine sparing nutrient, Membrin provides optimal dosages of three of the most well studied ingredients for targeted, multidimensional cognitive support. Suggested Use: 1 capsule per day or as recommended by your health care professional INGREDIENT BENEFITS Ginkgo Biloba Ginkgo biloba extract is the most well-studied botanical for cognitive support. In addition to protecting overall neuronal function, ginkgo biloba increases cerebral blood flow, and protects neurons from a variety of hypoxic conditions and oxidant-induced damage. Vinpocetine Synthesized from tabersonine, a natural extract from the seeds of the West African plant Voacanga africana, vinpocetine has recently been the subject of research related to cognitive health because of its neuroprotective mechanisms, including its antioxidant, and vasodilating activities. Vinpocetine has the ability to cross the blood brain barrier and has vasorelaxant effects on cerebral smooth muscle tissue. Huperzine A A purified component derived from Chinese club moss, huperzine A has been shown in research to improve memory and support optimal cognitive health.