Ortho Molecular Products

This will be fulfilled by a product that this manufacturer Private Labels for us By purchasing this product, you agree that you will be receiving OrthoMune in our new private-labeled bottle: Clear CV - Our own private labeled OrthoMune! By having Orthomolecular private label their great products for us, we are able to offer them to more people and receive/ship product in a more timely manner so YOU can get what you want, faster!!! OrthoMune/Clear CV is a balanced blend of flavonoids and crucial vitamins and minerals that provide safe, long-term immune support for all populations without overstimulating the immune system. OrthoMune/Clear CV is a targeted blend of nutrients designed to provide a broad-spectrum support to the body’s immune reserves. The formula includes quercetin, a powerful bioflavonoid that aids in supporting the immune system. Vitamin C and N-acetyl cysteine are potent antioxidants that promote respiratory function and support the function of quercetin. Vitamin D and zinc are important micronutrients needed to create a robust immune reserve. This powerful combination works to promote healthy respiratory and immune function. Vitamin D3 It has been shown that low vitamin D levels have immunologic implications with a significant decrease in immune function, affecting respiratory health.11,12,17 This is most likely because the vitamin D receptor is expressed by several immune cells including monocytes, macrophages, dendritic cells, B and T cells.18 Supplementation with vitamin D has been shown to modulate NK cell activity to promote a healthy innate immune response.15,19 Along with these immune-supporting benefits, vitamin D has also been shown to support the respiratory system and epithelial tight junction integrity.15,19,20,21 Zinc Zinc is essential for maintaining immune system integrity and healthy immune development.12,13,14 Supplementation with zinc supports key immune functions such as natural killer cell activity and phagocytosis by macrophages and neutrophils.15 Furthermore, studies show that zinc can directly support the body during immune system challenges and can help support healthy respiratory function.15,16 Vitamin C Vitamin C is a potent antioxidant that has been studied for many years for its immune-supporting effects. Through its antioxidant functions, vitamin C has been shown to protect important immune cells from oxidative damage.5 Data shows vitamin C is heavily concentrated in macrophages, supports lymphocyte activity, modulates cytokine release, improves endothelial function, restores mitochondrial function, and can directly support a challenged immune system.3 Of particular interest, vitamin C has been shown to recycle oxidized quercetin back to its parent compound, which supports a robust immune response while increasing the efficacy of quercetin.3,6 Quercetin Quercetin is best known for its antioxidant activity in scavenging free radicals. Additionally, quercetin helps balance the level of cytokines and improve T-lymphocyte balance. Several mechanism studies highlight quercetin’s ability to provide immune system support while also stimulating the ciliary beat frequency of the nasal epithelium, aiding the excretion of respiratory mucus.1,2,3 Quercetin has been shown to block the mechanisms by which microbes enter the host cells and replicate within the body.3 Additionally, a human clinical trial found quercetin supplementation supported healthy respiratory function following a stressor (i.e., intense bout of exercise), compared to placebo.4 N-acetyl cysteine (NAC) NAC is the precursor of the master antioxidant, glutathione. NAC has been shown to support mucus clearance and normal respiratory function, through its ability to cleave disulfide bonds in mucus.7,8 NAC is found to raise glutathione levels, which is important to protect the biologic activity and safe metabolism of quercetin.3,9 Along with protecting the activity of quercetin, NAC supports all detoxification pathways and helps maintain immune balance by supporting glutathione levels.10,11 Directions 2 capsules per day or as recommended by your health care professional.  Learn more about OrthoMune/Clear CV here >> ConnersClinic.com/blog   Studies on COVID-19 and Nutrition** US National Library of Medicine | National Institutes of Health: N-Acetylcysteine to Combat COVID-19: An Evidence Review US National Library of Medicine | National Institutes of Health: The prophylaxis and treatment potential of supplements for COVID-19 US National Library of Medicine | National Institutes of Health: Quercetin, Inflammation and Immunity FLCCC Alliance iMASK+: Preventions & Early Outpatient Treatment Protocol for COVID-19 References  1. Wu W, Li R, Li X, et al. Quercetin as an Antiviral Agent Inhibits Influenza A Virus (IAV) Entry. Viruses. 2015;8(1). 2. Mehrbod P, Hudy D, Shyntum D, Markowski J, Łos MJ, Ghavami S. Quercetin as a Natural Therapeutic Candidate for the Treatment of Influenza Virus. Biomolecules. 2020;11(1). 3. Colunga Biancatelli RML, Berrill M, Catravas JD, Marik PE. Quercetin and Vitamin C: An Experimental, Synergistic Therapy for the Prevention and Treatment of SARS-CoV-2 Related Disease (COVID-19). Frontiers in immunology. 2020;11:1451. 4. Nieman DC, Henson DA, Gross SJ, et al. Quercetin reduces illness but not immune perturbations after intensive exercise. Med Sci Sports Exerc. 2007;39(9):1561-1569. 5. Carr AC, Maggini S. Vitamin C and Immune Function. Nutrients. 2017;9(11). 6. Boots AW, Haenen GR, Bast A. Health effects of quercetin: from antioxidant to nutraceutical. European journal of pharmacology. 2008;585(2-3):325-337. 7. De Rosa SC, Zaretsky MD, Dubs JG, et al. N-acetylcysteine replenishes glutathione in HIV infection. European journal of clinical investigation. 2000;30(10):915-929. 8. Aldini G, Altomare A, Baron G, et al. N-Acetylcysteine as an antioxidant and disulphide breaking agent: the reasons why. Free Radic Res. 2018;52(7):751-762. 9. Rushworth GF, Megson IL. Existing and potential therapeutic uses for N-acetylcysteine: the need for conversion to intracellular glutathione for antioxidant benefits. Pharmacology therapeutics. 2014;141(2):150-159. 10. Grandjean EM, Berthet P, Ruffmann R, Leuenberger P. Efficacy of oral long-term N-acetylcysteine in chronic bronchopulmonary disease: a meta-analysis of published double-blind, placebo-controlled clinical trials. Clinical therapeutics. 2000;22(2):209-221. 11. Falluel-Morel A, Lin L, Sokolowski K, McCandlish E, Buckley B, DiCicco-Bloom E. N-acetyl cysteine treatment reduces mercury-induced neurotoxicity in the developing rat hippocampus. J Neurosci Res. 2012;90(4):743-750. 12. Linus Pauling Institute. Zinc. 2019; https://lpi.oregonstate.edu/mic/minerals/zinc#impaired-immune-function. Accessed January 7, 2021. 13. Baum, M. K., Shor-Posner, G., Campa, A. (2000). Zinc status in human immunodeficiency virus infection. The Journal of nutrition, 130(5S Suppl), 1421S–3S. https://doi.org/10.1093/jn/130.5.1421S 14. Maares, M., Haase, H. (2016). Zinc and immunity: An essential interrelation. Archives of biochemistry and biophysics, 611, 58–65. https://doi.org/10.1016/j.abb.2016.03.022 15. Rondanelli M, Miccono A, Lamburghini S, et al. Self-Care for Common Colds: The Pivotal Role of Vitamin D, Vitamin C, Zinc, and Echinacea in Three Main Immune Interactive Clusters (Physical Barriers, Innate and Adaptive Immunity) Involved during an Episode of Common Colds-Practical Advice on Dosages and on the Time to Take These Nutrients/Botanicals in order to Prevent or Treat Common Colds. Evidence-based complementary and alternative medicine : eCAM. 2018;2018:5813095. 16. Hemilä H. Zinc lozenges and the common cold: a meta-analysis comparing zinc acetate and zinc gluconate, and the role of zinc dosage. JRSM open. 2017;8(5):2054270417694291. 17. Ginde AA, Sullivan AF, Mansbach JM, Camargo CA, Jr. Vitamin D insufficiency in pregnant and nonpregnant women of childbearing age in the United States. Am J Obstet Gynecol. 2010;202(5):436.e431-438. 18. Sassi F, Tamone C, D’Amelio P. Vitamin D: Nutrient, Hormone, and Immunomodulator. Nutrients. 2018;10(11). 19. Prietl B, Treiber G, Pieber TR, Amrein K. Vitamin D and immune function. Nutrients. 2013;5(7):2502-2521. 20. Martineau AR, Jolliffe DA, Hooper RL, et al. Vitamin D supplementation to prevent acute respiratory tract infections: systematic review and meta-analysis of individual participant data. BMJ. 2017;356:i6583. 21. Shi, Y. Y., Liu, T. J., Fu, J. H., Xu, W., Wu, L. L., Hou, A. N., Xue, X. D. (2016). Vitamin D/VDR signaling attenuates lipopolysaccharide-induced acute lung injury by maintaining the integrity of the pulmonary epithelial barrier. Molecular medicine reports, 13(2), 1186–1194. https://doi.org/10.3892/mmr.2015.4685 **Disclaimer Regarding OrthoMune This information is for educational purposes only. We are not making the claim that OrthoMune or its ingredients can prevent or fight COVID-19. It is recommended that you do your own research and consult your physician before making any decisions on what to do for your health.

This may be fulfilled by a product that this manufacturer Private Labels for us CLINICAL APPLICATIONS Provides Safe, Highly Absorbed Iron for a Variety of Protocols High-Concentration Iron for Energy Support Supports Oxygen Transport and Energy Production OVERVIEW Iron is one of the most abundant minerals on earth. It is essential to the majority of life forms, especially human physiology. Iron supports prenatal and cognitive health, as well as energy balance. Iron is an integral component of the proteins involved in oxygen transport and storage: hemoglobin, myoglobin and ferritin. Iron, as part of the protein hemoglobin, carries oxygen from the lungs to various parts of the body. Hemoglobin accounts for nearly two-thirds of the iron found in the body, and carries essential oxygen to tissues and organs. Approximately one-sixth of the body’s iron is stored as ferritin for use when dietary intake is not sufficient. Iron must be maintained at balanced levels within the body – too much can cause toxicity and too little may lead to impairment of optimal health outcomes. Iron has to be carefully absorbed by the body. Interference can easily occur, making adequate consumption through diet and supplementation imperative to achieving a healthy balance. Reacted Iron provides 29 mg of elemental iron per serving, ideally formulated using the amino acid chelate form of iron (ferrous bisglycinate) for enhanced absorption, optimal utilization and gastrointestinal (GI) comfort. Some individuals, who take other forms of iron supplements, may experience GI side effects, including gas, bloating, constipation or a combination of these symptoms. Supplementing the right form of iron can be key to maintaining healthy levels within the body and compliance to a supplement regimen. Suggested Use: 1 capsule per day or as recommended by your health care professional INGREDIENT BENEFITS Iron Bioavailability The importance of bioavailability is obvious. If consuming an iron supplement has little effect on improving the body’s iron balance, there is no reason to ingest it. Signs of inferior mineral supplements include the use of cheap, poorly absorbed, rocksalt minerals. Reacted Iron is formulated with the superior amino acid chelate form, ferrous bisglycinate, which does not ionize in the gut. Like heme iron (the most bioavailable form of iron found in some protein food sources), Ferrochel® Ferrous Bisglycinate is not impacted by dietary factors and is absorbed at a 59% higher rate than lesser forms, such as ferrous sulfate. Comparison studies have shown significantly superior absorption of the iron chelate form compared to other rocksalt forms (most commonly ferrous sulfate): Ferrochel® iron shows absorption rates 59% higher than ferrous sulfate Ferrochel® iron is absorbed at a rate 3.8 times higher than ferrous sulfate Ferrochel® iron shows a reduced number of adverse complaints compared to ferrous sulfate No complaints of side effects were reported by subjects at 30 mg per serving

This may be fulfilled by a product this manufacturer Private Labels for us Note: We Private Label this product from Orthomolecular so you may receive it in our private label - Clear Hist Jr. It is the EXACT same product!!! CLINICAL APPLICATIONS Supports Immune Balance in Hypersensitive Individuals Supports Sinus and Respiratory Health Promotes Normal Viscosity of Mucus Clears Nasal Passages OVERVIEW D-Hist Jr. / Clear Hist Jr. is a great-tasting, chewable tablet that includes a targeted blend of flavonoids, antioxidants, proteolytic enzymes and botanicals designed to provide comprehensive support for children with seasonal challenges caused by common environmental allergens. D-Hist Jr. /Clear Hist Jr. includes quercetin, a powerful flavonoid to support healthy histamine levels. It supplies bromelain to enhance the absorption of quercetin and to support mucosal tissue health and stinging nettles leaf to balance hyper-immune response. N-acetyl cysteine clears the airways by promoting normal viscosity of mucus. This unique nutritional combination safely promotes healthy nasal and sinus passages for children with elevated histamine and respiratory irritation. Suggested Use: 1 tablet as needed or as recommended by your health care professional INGREDIENT BENEFITS Quercetin Quercetin is a biologically active flavonoid antioxidant that is widely distributed in plants, oak trees, onions and tea leaves. Quercetin has strong antioxidant activity and has also been shown to support immune health by mediating the release of inflammatory compounds, including leukotrienes and prostaglandins. Quercetin is known for its ability to stabilize mast cells, which diminishes the release of histamine, the compound known to cause hypersensitivity reactions during seasonal changes. Stinging Nettles Leaf Urtica dioica, commonly known as stinging nettles, is a plant that has been shown to balance immune response, specifically in the airways and nasal passages. Studies have shown that the extract of stinging nettles leaf balances several of inflammatory activities that affect respiratory health. In addition to controlling mast-cell degranulation, stinging nettles leaf controls prostaglandin formation and histamine action, thus contributing to a balanced inflammatory response. Bromelain Bromelain is a plant enzyme naturally found on the stem and fruit of the pineapple plant. Bromelain is a proteolytic enzyme that aids in in the breakdown of large protein complexes, including antigenic compounds. Bromelain has been shown to enhance the absorption of quercetin and to reduce circulating allergenic protein complexes associated with hyper-immune sensitivity and seasonal discomfort. N-Acetyl Cysteine N-acetyl cysteine (NAC) is an amino acid precursor to one of the most important antioxidants in the body: glutathione. Both glutathione and NAC help reduce the viscosity of the mucus allowing for clearing of the airways and improved respiratory health. Vitamin C Because vitamin C cannot be synthesized by the human body, it is an essential nutrient that must be consumed in the diet. Among its numerous health-promoting properties, vitamin C supports the immune system and is also a potent antioxidant. When the body is under a significant amount of stress, vitamin C is excreted rapidly. Vitamin C has many immune boosting properties, but is distinctively beneficial for individuals with seasonal discomfort because of its ability to deactivate histamine.

This may be fulfilled by a product that this manufacturer Private Labels for us We Private Label Orthomolecular's SBI Protect as our Clear SBI Pro. By purchasing this product you are agreeing to receive it as our private labeled Clear SBI Pro. It is the exact same product the Orthomolecular packages and labels for us. SBI Protect is the only purified, dairy-free source of immunoglobulin G (IgG) available as a dietary supplement. Pure IgG helps to maintain a healthy intestinal immune system by binding a broad ranges of microbes and toxins within the gut lumen. CLINICAL APPLICATIONS Provides Concentrated Immunoglobulins to Enhance Mucosal Immunity Helps Maintain Microbial Balance Supports GI Barrier Health and Integrity Helps Maintain Normal Inflammatory Balance OVERVIEW The discovery that the gut barrier plays a key role in immune health fueled the search to strengthen it. In that search, researchers found that the binding capabilities of immunoglobulins have a positive effect on gut barrier function. Immunoglobulins bind microbes and toxins in the GI tract and eliminate them prior to immune system activation. As these unwanted triggers are removed, it resets healthy immune tolerance and builds a stronger barrier to the external environment. Suggested Use: 1 scoop (2.5 grams) in 4 ounces of water or the beverage of your choice 2 times daily or as recommended by your health care professional. INGREDIENT BENEFITS SBI and GI Health SBI has been shown to bind microbes and toxins, further enhancing microbiome balance and facilitating gut barrier strength. Broad-spectrum binding capabilities demonstrate the positive influence of non-allergenic forms of immunoglobulins. As seen in several studies, SBI has the potential to bind many types of microbes and toxins. This binding and elimination decreases microbe and toxin encounters by the immune system and resets immune tolerance. SBI and Immune Health In studies evaluating the effect of SBI on immune function, subjects showed positive outcomes in several areas, including inflammatory balance, gut barrier function and immune cell counts. In an open-label human clinical study, GI-challenged patients were given 2.5 mg SBI twice daily. They had increased CD4+ counts in the duodenum after eight weeks, indicating a regenerative effect on the tissue and immune function in the intestines. ALSO, check out this product in our: GUT HEALING BUNDLE - PROTOCOL #1 (FOR THOSE WITH A HISTORY OF CANCER OR GLUTAMATE ISSUES) - YOU RECEIVE ALL 5 PRODUCTS IN THIS BUNDLE GIVING YOU A 10% SAVINGS OVER INDIVIDUAL PRODUCT PURCHASE.

This may be fulfilled by a product that this manufacturer Private Labels for us Clear Estro DIM Pro / CDG EstroDIM is a targeted supplement that combines the synergistic benefits of the cruciferous vegetable metabolites Indole-3-carbinol (I3C) and diindolylmethane (DIM) to support proper estrogen metabolism. Formulating I3C and DIM together creates the ideal combination of beneficial metabolites to support estrogen balance and breast and prostate health. We Private Label Orthomolecular's CDG EstroDIM as our Clear Estro DIM Pro. By purchasing this product you are agreeing to receive it as our private labeled Clear Estro DIM Pro. It is the exact same product the Orthomolecular packages and labels for us. The Health Benefits of Cruciferous Vegetable Metabolites† Many of the health benefits derived from eating cruciferous vegetables (cabbage, brussels sprouts, broccoli, etc.), especially those that may be beneficial for breast and prostate health, are thought to be derived from the group of secondary metabolites known as glucosinolates. When these vegetables are cut, crushed or chewed the enzyme myrosinase (released from the cells) hydrolyses these glucosinolates into other compounds. For instance, glucosinolates from broccoli and brussel sprouts readily convert into I3C when consumed. I3C can then be further converted via stomach acid into other health promoting compounds, including DIM. These compounds are generally thought to be responsible for the various cellular activities that lead to hormone health. Overview Estrogen collectively refers to the female hormones estradiol, estrone and estriol. Hormones have important functions in every area of the body. They are chemical messengers that interact with cells all over the body (especially tissues that are more sensitive to them, including breast and prostate tissues). The most important message they deliver to cells is to grow, divide and multiply. For this reason, hormones are critically important in human development and tissue repair. Supporting proper estrogen synthesis, metabolism and detoxification is essential for proper hormonal balance. The means in which estrogen is metabolized can result in different metabolites, each with individual biological activity. By keeping hormones in balance and ensuring the body is able to process hormones properly, cruciferous vegetable metabolites (such as I3C and DIM) work together to reduce hormone overload and maintain cellular health. Current data on I3C and DIM suggests that these phytonutrients have strong potential for supporting breast, cervical, uterine and prostate health.1-4 Together, I3C and DIM promote the creation of the favorable and protective 2-hydroxyestrone (2-OHE) metabolite versus production of 4-hydroxyestrone (4-OHE) and 16-alpha-hydroxyestrone (16-alphaOHE), metabolites which can overstimulate cells and create free radicals that cause DNA damage.5 The influence of I3C and DIM on estrogen metabolism creates a more desirable ratio of 2-OHE to 16-alpha-OHE. This assessment of 2:16-alpha- OHE ratio has been used to evaluate breast health. With this in mind, CDG EstroDIM includes targeted doses of both I3C and DIM in a two capsule per day dosing to make daily balancing of hormones easy and convenient. I3C† I3C (indole-3-carbinol) is a naturally occurring compound found in numerous cruciferous vegetables, such as broccoli, cauliflower, kale and cabbage. Following ingestion of I3C, the body converts it to several different metabolites, one of which is diindolylmethane (DIM). Both of these compounds, as well as many other I3C metabolites, have been shown to impact metabolic shifts and cellular activities for improved health outcomes. I3C has also been shown to temper estrogen signals by competing for binding sites and inhibiting the activity of estrogen receptors.6-15 A study published in the Journal of Nutrition unveiled evidence that I3C supports healthy cellular function related to estrogen metabolism.16 DIM† Diindolylmethane (DIM) is a phytonutrient and plant indole also found in cruciferous vegetables with potential for enhancing proliferation of healthy cells and cellular activities. As a dimer (formed chemical structure of two substances) of indole-3-carbinol, DIM promotes beneficial estrogen metabolism in both sexes supporting the formation of healthy estrogen metabolites and enhancing the potential for greater antioxidant activity.17-19 Calcium D-Glucarate † Calcium D-Glucarate is the supplemental calcium salt form of D-glucaric acid, a substance produced naturally in the body and obtained through consumption of certain fruits and vegetables. Calcium D-glucarate has been extensively studied and has been shown to inhibit beta-glucuronidase, an enzyme found in certain bacteria that reside in the gut. This activity supports the body’s ability to detoxify estrogens, foreign molecules and fat-soluble toxins.20-23 Directions 2 capsules per day or as recommended by your health care professional. Does Not Contain Wheat, gluten, corn, yeast, animal or dairy products, fish, shellfish, peanuts, tree nuts, egg, artificial colors, artificial sweeteners or preservatives. Cautions Do not consume this product if you are pregnant or nursing.

This may be fulfilled by a product that this manufacturer Private Labels for us Phase 6 Assist / Super Aloe 250 is intended for the relief of occasional constipation. Cape aloe, the solid residue obtained by evaporating liquid aloe vera, has been shown in research to affect regularity, due to its influence on colon peristalsis, which it triggers to contract, resulting in accelerated intestinal passage.  Cape aloe has been used for thousands of years to promote the health of epithelial tissue, including the bowel lining. Cape aloe is one of a class of compounds called anthraquinone glycosides. When ingested, these molecules are activated through bacterial metabolism in the gut. They promote water retention in the stool and stimulate peristalsis in the large intestine. By stimulating active chloride secretion, aloe increases the water and electrolyte content in the stool1-4 and eases its passage without the artificial additives and associated cramping common to other therapies. Free Download - The 7 Phases of Detox

Ortho Spore IG™ is a spore-based, broad-spectrum probiotic formula designed to promote a healthy gut microflora, protect mucosal integrity, and relieve small intestinal bacterial overgrowth (SIBO). Uniquely included in this formula are serum-derived bovine immunoglobulins that bind to and eliminate microbes and toxins that are common in SIBO. Clinical Applications Helps Maintain Normal Gastrointestinal Balance Provides Concentrated Immunoglobulins to Enhance Mucosal Immunity Supports Digestion and Micronutrient Absorption Maintains GI Barrier Health and Integrity Overview SIBO is a condition that occurs when there is an overabundance of commensal bacteria from the colon present in the small intestine. The health of the small intestines relies on balanced microbiota, and probiotics and immunoglobulins can contribute to that balance by having a positive influence on the intestinal environment, including pH, organism diversity, and immune signaling. Probiotics have been extensively studied and are characterized as having broad GI and immune benefits. Probiotics are live organisms and must be shelf stable through the expiration date, so they can be precisely delivered to the intestinal tract to have maximum benefit. Bacillus spores remain dormant in harsh environments until they reach more favorable environments like the human gastrointestinal tract. The combination of specific strains, particularly Bacillus coagulans, Bacillus clausii, and Bacillus subtilis, relieve symptoms for common GI complaints and reinforce healthy gut function. In the search for innovative ways to improve microbiome diversity, we have combined our blend of spore-forming probiotics alongside immunoglobulins uniquely shown to bind to bacteria and toxins, driving immune response. IgG helps to maintain a healthy intestinal immune system by binding a broad range of microbes and toxins within the gut lumen. Suggested Use 3 capsules per day or as recommended by your health care professional. Guaranteed potency at expiration. No refrigeration required. INGREDIENT BENEFITS Bacillus coagulansBacillus coagulans has been shown to increase the commensal GI microbiota. B. coagulans also significantly improved bowel movements in healthy adults with occasional constipation, as well as decreased abdominal discomfort. Bacillus clausiiB. clausii is commonly used as a probiotic to promote balance in the microbiome and has showed promising results in individuals with SIBO. Bacillus subtilisBacillus subtilis has been shown to relieve GI distress in patients. Serum-derived bovine immunoglobulinsBroad-spectrum binding capabilities demonstrate the positive influence of serum-derived bovine immunoglobulins. This binding and elimination decreases microbe and toxin encounters by the immune system and resets immune tolerance. Free Download - The 7 Phases of Detox

This may be fulfilled by a product that this manufacturer Private Labels for us Dr. Conners recommends Motility Pro for help with what he calls, Phase 4 of the detoxification process. We Private Label Orthomolecular's Motility Pro as our Phase 4 Assist. By purchasing this product you are agreeing to receive it as our private labeled Phase 4 Assist. It is the exact same product the Orthomolecular packages and labels for us. Motility PRO / Phase 4 Assist is a patented combination of ginger (Zingiber officinale) and artichoke leaf extract (Cynara cardunculus L.) delivered at a clinically proven dose to restore gastric motility, improve digestion, and relieve temporary gastric discomfort. This distinctive blend of bioactives promotes contractions in the migrating motor complex, helping to restore proper motility, which ensures the steady flow of food particles and bacteria through the small intestine. In addition, it provides support for improved digestion and relief from gas, bloating and associated GI discomfort. Free Download - The 7 Phases of Detox

CLINICAL APPLICATIONS Promotes Healthy Microbial Balance Helps Maintain Gastro-Intestinal Comfort Provides Nutrients that Increase Antioxidant Protection Enhances Immune Function OVERVIEW Gastrointestinal health is directly affected by factors like poor diet and a stressful lifestyle. The prevalence of refined sugars and carbohydrates and lack of fiber in Western diets have been directly linked to changes in the intestinal and colonic environments. Since more than 70% of the body’s immune system resides in the gut, establishing a healthy microbial balance is critical in reducing immune challenges and maintaining inflammatory balance. Candicid Forte provides a blend of nutrients, potent botanicals and essential oils to promote healthy microbial balance and immune support. Formulated with the goal of building a healthy gastrointestinal (GI) flora, Candicid Forte includes biotin, a nutrient that inhibits yeast from converting into the more aggressive fungal form. In addition, sodium caprylate is included to disrupt the metabolism of Candida and create a hostile environment for colonization. It also includes potent botanicals, such as berberine HCl, Pau d’Arco, oregano, rosemary, cinnamon and ginger, to sooth the GI tract, provide potent antioxidant support, and ensure microbial balance. Suggested Use: 2 capsules three times per day or as recommended by your health care professional INGREDIENT BENEFITS Biotin Biotin is a water-soluble vitamin and cofactor for carboxylases; the nutrient affects several key systemic functions such as tissue growth, development, immunity and metabolism. Deficiencies in biotin have also been linked with mild immune impairment. The role that biotin can play in the GI tract is primarily based on its ability to establish microflora balance by preventing yeast, especially Candida albicans, from converting to its more invasive fungal form. In the presence of biotin, yeast is unable to change into the mycelium form. Oregano Phytonutrients from oregano, such as rosmarinic acid and quercetin, have been shown to play a role in supporting antioxidant mechanisms and healthy microbial balance in the body. In addition, the high ORAC (oxygen radical absorbance capacity), on a scale developed by scientists at the National Institute of Aging) value of oregano, indicates its significant antioxidant-scavenging capacity to combat free radicals that cause oxidative stress. Oregano oil also contains two naturally occurring microbial balancing agents named carvacrol and thymol. Research suggests that these compounds relieve GI dysbiosis and promote a healthy GI microflora. Pau d’Arco The inner portion of the Pau d’Arco bark has been used by Native Americans for thousands of years to support intestinal microbial health. The herb has been shown to be effective in promoting healthy intestinal flora and is recommended by herbalists for a wide variety of GI challenges. Studies have shown that Pau d’Arco may also balance musculoskeletal inflammation and in vitro studies have shown fractions from Pau d’Arco support microbial balance. Sodium Caprylate Sodium Caprylate is the stable sodium salt of caprylic acid, a fatty acid found in coconuts. In vitro studies show that sodium caprylate inhibits aerobic and anaerobic growth, provokes loss of cytoplasm organization and organelles, inhibits budding, triggers potassium loss, and is destructive to the cellular integrity of Candida albicans. Caprylic acid has been shown to contribute to microbial balance. Berberine HCl An alkaloid extracted from plant roots, berberine has been found to express strong microbe balancing activity in vitro, and was found to be the best of four agents studied in inhibition of Candida albicans’ adherence to HT-29 epithelial cells. Berberine was also found to inhibit SAP (secreted aspartyl proteinases) activity by 70.2% +/-6%, a marker of yeast conversion to the aggressive fungal form. In one in vitro study, mice given 1 mg/kg body weight of berberine had a potent effect on microbial balance, and displayed synergistic effects with fungal balancing agents. Rosemary The essential oil of rosemary has been shown to exhibit broad-spectrum microbial balancing effects. The oil was analyzed in vitro for its microbial balancing and antioxidant activities and was found to have strong activity. Rosemary extract has also been shown to decrease oxidative stress in various tissues. Cinnamon Bark Extract In an in vitro study looking at different strains of microbes, including MRSA and Candida species, the essential oil of cinnamon showed consistent ability to maintain microbial balance. In vitro research has shown that cinnamon extract causes a change in cell morphology, destruction of organelles and cellular burst when microbes are exposed to the essential oils of cinnamon.