Ortho Molecular Products

CLINICAL APPLICATIONS Supports Immune Balance in Hypersensitive Individuals Supports Sinus and Respiratory Health Promotes Normal Viscosity of Mucus Clears Nasal Passages OVERVIEW Natural D-Hist is a targeted blend of flavonoids, antioxidants, proteolytic enzymes and botanicals designed to provide comprehensive support for seasonal challenges caused by common environmental allergens. The formula includes quercetin, bromelain, stinging nettles leaf, and N-acetyl cysteine. The powerful combination actively promotes healthy nasal and sinus passages for individuals with elevated histamine and respiratory irritation. Suggested Use: Loading Dose: 2 capsules three times per day for 7-10 days or as recommended by your health care professional Maintenance: 1 or more capsules per day or as recommended by your health care professional INGREDIENT BENEFITS Quercetin Quercetin has strong antioxidant activity and has been shown to support immune health by mediating the release of inflammatory compounds including leukotrienes and prostaglandins. Quercetin is known for its ability to stabilize mast cells, diminishing the release of histamine, the compound known to cause hypersensitivity reactions during seasonal changes. Stinging Nettles Leaf Extract Stinging nettles leaf is a plant that has been shown to balance immune response, specifically in the airways and nasal passages. Studies have shown that the extract of stinging nettles leaf balances a variety of inflammatory activities that affect respiratory health. Bromelain Bromelain is a plant enzyme naturally found on the stem and fruit of the pineapple plant. Bromelain is a proteolytic (protein-digesting) enzyme that aids in in the breakdown of large protein complexes, including antigenic compounds, and has been shown to enhance the absorption of quercetin. Bromelain has been shown to reduce circulating allergenic protein complexes associated with hyper-immune sensitivity and seasonal discomfort. N-Acetyl Cysteine N-acetyl cysteine (NAC) is an amino acid precursor to one of the most important antioxidants in the body, glutathione. Both glutathione and NAC help reduce the viscosity of the mucus allowing for clearing of the airways and improved respiratory health.  Vitamin C Vitamin C cannot be synthesized by humans and is therefore an essential nutrient that must be consumed in the diet. Among its numerous health-promoting properties, vitamin C is an essential vitamin that supports the immune system and is also a potent antioxidant. When the body is under a significant amount of stress, vitamin C is excreted rapidly. Vitamin C has many immune boosting properties, but is distinctively beneficial for individuals with seasonal discomfort because of its ability to deactivate histamine. *This item may take longer to ship*

CLINICAL APPLICATIONS Provides Protection for Neurons from Free Radical Damage Enhances Cerebral Blood Flow and Cognitive Health Provides Targeted Antioxidant Support for the Brain OVERVIEW Maintaining cognitive function is an increasingly important challenge with the aging United States population. Aging is often associated with functional changes in the brain that can affect event recall ability, thought organization, and ability for self-expression. While some memory loss is common in the aging population, factors such as free-radical damage, nutrient deficiencies, lifestyle choices and emotional stress are known to affect cognition with age. The brain is part of the nervous system, which is made up of neurons responsible for processing and transmitting information using neurotransmitters and electrical ion channels. Maintaining the function of various aspects of neuron communication is integral to maintaining optimal cognitive function.  Membrin provides vinpocetine and ginkgo biloba to support cerebral blood circulation, decrease excitotoxicity and scavenge damaging free radicals. In addition, vinpocetine has specifically been shown to inhibit phosphodiesterase, and therefore helps increase cerebrvascular blood flow and improve memory. Together with huperzine A, a potent acetylcholine sparing nutrient, Membrin provides optimal dosages of three of the most well studied ingredients for targeted, multidimensional cognitive support. Suggested Use: 1 capsule per day or as recommended by your health care professional INGREDIENT BENEFITS Ginkgo Biloba Ginkgo biloba extract is the most well-studied botanical for cognitive support. In addition to protecting overall neuronal function, ginkgo biloba increases cerebral blood flow, and protects neurons from a variety of hypoxic conditions and oxidant-induced damage. Vinpocetine Synthesized from tabersonine, a natural extract from the seeds of the West African plant Voacanga africana, vinpocetine has recently been the subject of research related to cognitive health because of its neuroprotective mechanisms, including its antioxidant, and vasodilating activities. Vinpocetine has the ability to cross the blood brain barrier and has vasorelaxant effects on cerebral smooth muscle tissue. Huperzine A A purified component derived from Chinese club moss, huperzine A has been shown in research to improve memory and support optimal cognitive health.

Orthomega® provides 820 mg of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) as well as 50 mg of docosapentaemoic acid (DPA) per soft gel as natural triglycerides, the preferred form with superior absorption. Vitamin E (as mixed tocopherols) and rosemary extract are used to ensure maximum purity and freshness. Clinical Applications Supports Cardiovascular Health and Blood Sugar Metabolism Supports Cognitive Function and Development Supports Healthy Skin, Joints and Connective Tissues Increases Visual and Ocular Health Maintains Normal Inflammatory Balance Omega-3 fatty acids are essential cornerstones of human nutrition. They are deemed "essential" because we need them for proper health-much like certain vitamins and minerals but cannot produce them on our own. We must therefore consume these fats through diet or supplementation. Since omega-3 fatty acids are known to benefit cardiovascular health, support healthy brain function and cognition, and have also been proven to maintain a healthy inflammatory response, achieving the proper balance of omega-3s has become an important health strategy, requiring supplementation for most people. The American Heart Association recommends that those concerned about blood lipids take up to 4 g of omega-3 fatty acids per day.  Orthomega® 820 is a high-concentration fish oil sourced from waters off the Chilean coast. As the world’s least industrialized coastline, these cold, fresh waters provide the cleanest, most sustainable source of fish in the world. Orthomega® provides 820 mg of eicosapentaenoic acid (EPA)and docosahexaenoic acid (DHA) as well as 50 mg of docosapentaemoic acid (DPA) per soft gel as natural triglycerides, the preferred form with superior absorption. To stabilize the oil, vitamin E (as mixed tocopherols) and rosemary extract are used to ensure maximum purity and freshness. This exclusive fish oil is purified, vacuum distilled, and independently tested to ensure heavy metals, pesticides and polychlorinated biphenyls (PCBs) are removed to undetectable levels. With over 10,000 published studies in the last three decades, EPA and DHA from fish oil are among the most researched natural ingredients available and have a long history of safety and efficacy. Suggested Use: 1 soft gel capsule per day or as recommended by your health care professional

Clinical Applications Supports Healthy Digestion and Maximizes Nutrient Absorption Targeted Enzyme Support for Food Sensitivities Designed to Enhance the Benefits of a Plant-Rich Diet Stimulates the Release and Production of Natural DigestiveEnzymes in the Pancreas Supports Gastric Acid Balance and Digestive Function Because of our hectic lifestyle, and the way we often consume food that is frequently overcooked, digestion can often be less than optimal. A thorough digestion of foodstuffs with enzymes prevents foods from being fermented in the gut and the proliferation of “bad” bacteria and yeast at the expense of “good” intestinal bacteria. Another benefit of enzymes is that more nutrition can be derived from food. In addition, regular bowel movements result from this better digestion. Digestzyme-V is specifically designed to support digestion and help unlock more nutrition from food. Digestzyme-V is a comprehensive blend of acid-resistant, plant-based enzymes designed to help maximize the digestion and absorption of nutrients from food. Each capsule includes lipase, amylase, lactase, CereCalase® and protease to aid in the digestion of protein, fat, starches, fiber and other difficult to digest foods known to cause food sensitivities. CereCalase®, a special blend of hemicellulase, beta-glucanase and phytase, is specially formulated to digest the cell walls of plants, providing better nutrition from a plant-based diet. Digestzyme-V also includes Gentian root, a traditional bitter herb, and artichoke, a natural choleretic, added to stimulate the body’s natural production of enzymes and bile. Suggested Use: 1-2 capsules 15 minutes before a meal or as recommended by your health care professional

Dr. Conners has found a FAR SUPERIOR product: TheralacPRO Professional-only version of Theralac. TheralacPRO contains 50 billion CFU of Lactobacilli and Bifidobacteria probiotic cultures for complete intestinal coverage. The strains synergize and work together to promote digestive health throughout your digestive system so you can feel your best! Overview The GI tract is a finely balanced environment where roughly 500 different strains of bacteria compete for space and nutrients. When there is a healthy balance (eubiosis), few symptoms exist. However, dysbiosis can occur when an overabundance of potentially harmful organisms prevail. The natural microflora balance can be upset by medications (such as antibiotics, oral contraceptives, etc.), excessive alcohol consumption, or poor dietary intake. Probiotics have been extensively studied and are characterized as having broad GI and immune benefits, including increasing the population of healthy bacteria following microflora imbalance; supporting healthy bowel function; increasing the production of short-chain fatty acids, which provide energy to the cells of the intestinal lining; strengthening the gut-immune barrier by promoting a healthy gut mucosa; aiding in the digestion of difficult-to- breakdown compounds like lactose and casein; and enhancing detoxification of harmful compounds. Because probiotics are live organisms, there are many challenges associated with manufacturing and distributing probiotic supplements. For a probiotic to be effective, it must be shelf-stable through the expiration date and precisely delivered to the intestinal tract, where it can have maximum benefit.  Free Download - The 7 Phases of Detox

Super Aloe is intended for the relief of occasional constipation. Cape aloe, the solid residue obtained by evaporating liquid aloe vera, has been shown in research to affect regularity, due to its influence on colon peristalsis, which it triggers to contract, resulting in accelerated intestinal passage. Super Aloe is available as 250 and 450 mg capsules, two potencies to provide tailored natural support for elimination. Cape aloe has been used for thousands of years to promote the health of epithelial tissue, including the bowel lining. Cape aloe is one of a class of compounds called anthraquinone glycosides. When ingested, these molecules are activated through bacterial metabolism in the gut. They promote water retention in the stool and stimulate peristalsis in the large intestine. By stimulating active chloride secretion, aloe increases the water and electrolyte content in the stool1-4 and eases its passage without the artificial additives and associated cramping common to other therapies. Free Download - The 7 Phases of Detox

CLINICAL APPLICATIONS Provides Support for Healthy Urinary Tract Function Supports Healthy Microbial Balance in the Urinary Tract Helps Maintain a Healthy Mucosal Surface in the Urinary Tract Promotes Healthy Immune Function OVERVIEW UT Defense is a formula designed to support kidney and urinary tract health and to help to promote microbial balance. The formula includes Anthocran®, a cranberry extract which standardized to 36 mg proanthocyanidins (PACs), which makes it has been shown to be the optimal daily dose for urinary tract health. UT Defense also includes dandelion leaf extract, a natural diuretic and Ellirose™, an extract of hibiscus flower shown to promote healthy microbial balance in the urinary tract. Each capsule of UT Defense includes 120 mg Anthocran®, 225 mg dandelion leaf extract and 200 mg Ellirose™. Suggested Use: 1 capsule per day or as recommended by your health care professional INGREDIENT BENEFITS Anthocran® and Ellirose™ UT Defense includes Anthocran®, a concentrated source of proabtocyanidins (PACs), and Ellirose™, an extract of hibiscus flower. Both have been shown to support urinary tract health by promoting microflora balance. Dandelion Leaf Extract Dandelion leaf extract promotes healthy urinary tract function by providing support for natural urinary flow.

NOTE: If this product is on Backorder, consider Whole Body Collagen Powder CLINICAL APPLICATIONS Protects and Promotes Connective Tissue Biosynthesis Supports the Body’s Processes of Cartilage, Tendon, Ligament and Fascia Self-Repair Supports Joint Lubrication, Joint Cushioning, and Normal Connective Tissue Inflammatory Response Supports Normal Rejuvenation of Healthy Hair, Skin and Nails OVERVIEW Over time lifestyle factors can cause reduced elasticity in cartilage, tendons, ligaments and skin. This not only leads to wrinkles and decreased dermal matrix, but to soft tissue and joint discomfort. FORTIGEL® has been shown in human studies to stimulate collagen regeneration, type II collagen and aggrecan, which all help to maintain healthy connective tissue. Most therapies simply block joint pain and connective tissue discomfort, and in doing so inhibit the regeneration and elongation of specific precursors, such as polysaccharides, and deplete nutrients such as vitamin C and magnesium that maintain joint and connective tissue health. FORTIGEL®, TendoActive® and Mobilee® protect and preserve cartilage, tendons, ligaments, intervertebral discs, and fascia. These patented ingredients support the natural healing process and maintain the structure of connective tissues. Suggested Use: 1 scoop (7.6 grams) in 8 oz of water or the beverage of your choice per day or as recommended b your health care professional. Can also be added to food and baking products. INGREDIENT BENEFITS Collagen Hydrolysate as FORTIGEL®, is backed by more than fifteen studies, provides bioactive collagen peptides (BCPs), which contain high concentrations of specific peptides that comprise connective tissue. The precise length of the short-chain peptides and their low average molecular weight allows easy absorption, transport, and accumulation to target connective tissue. FORTIGEL® provides 5 g hypoallergenic protein per serving from a sustainable protein source without the risk of oxalate kidney stones from higher-dose collagen products. Clinical studies on FORTIGEL® demonstrate joint and tendon health benefits. Hyaluronic Acid Extract as Mobilee®, is a patented rooster comb extract rich in high molecular weight hyaluronic acid (HA), which is responsible for the viscoelastic, lubricating properties of synovial fluid. This extract also contains collagen and other glycosaminoglycans (GAGs). Hyaluronic acid also plays a role in the biophysical, biochemical and cell regulation processes in joint synovial tissues. Scientific evidence shows Mobilee® supports chrondrocytes and synovial cell function, and is two to four times more active than regular HA in supporting synovial fluid health. The latest clinical research includes HA in proactive and maintenance approaches to joint care and supports normal range-of-motion. Research suggests Mobilee® supports the quality of synovial fluid by positively influencing synovial HA concentration, and by reducing the expression of degradative factors in synovial fluid. Type I Collagen and Mucopolysaccharides as TendoActive®, is a combination of type I collagen and mucopolysaccharides. Adult tendons, ligaments and fascial tissue are comprised mainly of type I collagen molecules organized into structural units. The molecular structure and organization of tendon, ligament and fascial collagen fibrils are key determinants in the ability of these tissues to endure mechanical force and fuel self-repair. While collagen provides much of tendon/ligament structure and strength, mucopolysaccharides are the “glue” that holds them together and allows them to stretch, flex, bend and maintain their resilience. Mucopolysaccharides are a critical component of extracellular matrix and are important in maintaining structural integrity, lubrication and spacing of collagen fibers. Furthermore, mucopolysaccharides have been shown to increase collagen and non-collagenous protein synthesis in cultures of bovine tenocytes and ligament cells. TendActive® has been shown to be efficacious in medial and lateral epicondyle tendon patients, Achilles tendon patients and plantar fascia patients. Cofactor support for optimal connective tissue support and collagen production is provided by vitamin C and magnesium in the highest bioavailable form as Albion TRAACS® Magnesium Bisglycinate Chelate. Vitamin C not only protects connective tissue from free radical damage, but is critical for peptide folding and tri-helical peptide pro-collagen fiber formation before they are exported from the cytoplasm for final fiber trimming. Magnesium also plays a critical role as a cofactor for every enzyme involved in collagen formation, as well as balancing MMP and TIMP enzyme activity for optimal degradation and formation. *This product may take longer to ship out*

Bergamot Bioactive Polyphenolic Fractions (BPF) contains a powerful and unique array of cholesterol-balancing and cardio-protective polyphenolic flavonoids. Emerging clinical research has demonstrated that BPF help maintain healthy total cholesterol (TC), high density lipoprotein (HDL), low density lipoprotein (LDL), very low density lipoprotein (VLDL) and triglyceride (TRI) levels. Research has also demonstrated that BPF provides antioxidant-balancing properties and maintains normal inflammatory balance to help preserve coronary arteries. Overview Optimizing cardiovascular health is a leading concern for many adults, and maintaining balanced cholesterol levels are an important part of that process. Though cholesterol can be consumed through food, circulating cholesterol levels are primarily produced and controlled by the liver using the rate control enzyme, HMG-CoA reductase (HMGCR). Because of its pronounced role in cholesterol synthesis, inhibiting HMGCR has become a primary target of many traditional therapies. Numerous clinical trials have shown the specific BPF found in Bergamot BPF works at the level of the liver to help maintain and support healthy cholesterol levels and preserve coronary arteries by maintaining normal inflammatory balance. What are Bergamot Polyphenolic Fractions? Bergamot (Citrus bergamia) is a citrus plant that grows almost exclusively in the narrow coastal Calabria region in southern Italy. The local population quickly discovered bergamot juice could be used to help support healthy cholesterol levels and optimize cardiovascular wellness. Bergamot’s health benefits derive from its unique profile of phenolic compounds such as, neoeriocitrin, neohesperidin, naringin, rutin, neodesmin, rhoifolin and poncirin. Naringin has been shown to be beneficial in maintaining normal inflammatory balance, while neoeriocitrin and rutin have been found to exhibit a strong capacity to quench free radicals and maintain healthy LDL cholesterol levels. Also, bergamot is rich in brutieridine and melitidine, which have a unique ability to dampen HMG-CoA reductase. Using a patented extraction technology through collaborative works of various universities and research institutions, Bergamot BPF contains Bergamonte®, the highest concentration available of these potent phenolic compounds. Cholesterol-Balancing Properties In a placebo-controlled, clinical trial consisting of 77 patients divided into four treatment groups, 1,000 mg of BPF helped maintain healthy levels of all blood lipid markers (HDL, LDL, TC, TRI).1 Also, this same clinical trial showed that BPF activated the inflammatory-balancing enzyme AKT and reduced malondialdehyde production in neutrophils.1 Another clinical trial conducted on 80 patients over six months showed 1,500 mg of BPF maintained normal levels of small density LDL and supported normal carotid IMT thickness.2 In a placebo- controlled study involving 238 patients, 1,000 mg of BPF maintained healthy cholesterol levels and outperformed the group receiving the traditional therapy. Following a 60-day wash out phase in patients who had been on traditional therapies, 1,500 mg of BPF maintained normal LDL levels and optimized several other parameters of cardiovascular health.3 Several other recently published placebo-controlled clinical trials have also documented that BPF can help maintain normal inflammatory balance, antioxidant potential, healthy cholesterol levels, and CoQ-10 levels in humans.  

Note: Typical recommended dose for acute sinus infections is 9/day for a few days then drop to 3/day The standardized nutrients and botanicals in Sinatrol help support microflora balance, promote normal mucus viscosity for healthy sinus function, and promote a balanced inflammatory response. CLINICAL APPLICATIONS Provides Immediate Support for Sinus and Respiratory Challenges Maintains Optimal Sinus Clearance Boosts Immune Response Aids in the Breakdown of Mucus Helps Soothe the Sinuses OVERVIEW Optimal sinus health requires proper circulation through the sinus cavities that is free of mucus build-up. The sinuses are composed of hollow cavities that are lined with soft tissue, called mucosa. Under healthy conditions, the sinuses are empty and contain a thin layer of mucus. A healthy process that occurs in the sinus cavities, termed mucociliary clearance, allows the ciliated epithelium (hair-like structures located on tissues), in coordination with mucus production, to continually remove waste from the sinuses by facilitating drainage and particle removal. Typical particles that collect in the sinus cavities include dust, pollen, dirt, allergens and fungi. Sinatrol contains a synergistic blend of ingredients that support sinus health by increasing mucociliary clearance, decreasing the build-up of mucus and boosting immune response during seasonal respiratory challenges. Sinatrol is a specialized preparation of botanicals and nutrients formulated to support immune health and provide immediate support for respiratory challenges. The standardized botanicals and nutrients in Sinatrol target sinus related issues by clearing airway passages, decreasing the viscosity of mucus and supporting immune health. Suggested Use: 3 capsules per day or as recommended by your health care professional INGREDIENT BENEFITS N-Acetyl Cysteine N-acetyl cysteine (NAC) is a powerful amino acid that dissolves mucus by breaking up disulfide bonds which make up the protein network that contributes to mucus density. This results in improved drainage out of the sinus cavity. In a double-blind study examining 12 healthy volunteers with slow mucociliary clearance, NAC administration for 60 days resulted in a 35% increase in mucociliary clearance rate in treated subjects, compared to no improvement in the placebo group. Additional studies have also demonstrated an improvement in mucus clearance following NAC administration. Turmeric Root (Complete Turmeric Matrix) Whole-root turmeric and its active compounds have been used in traditional Ayurvedic Medicine for centuries. New research on turmeric shows that more than curcumin, additional turmeric bioactives in turmeric have added benefits and enhance bioavailability. Sinatrol offers a full spectrum turmeric ingredient with an exclusive blend of bioactive turmeric nutrients. The complete turmeric matrix formula provides a comprehensive systemic effect where it maintains normal inflammatory balance, supports microbiome diversity and balances immune function. Bromelain Bromelain is a plant enzyme that is naturally found in the stem and fruit of the pineapple plant. Bromelain exerts a synergistic effect when combined with NAC due to its proteolytic (protein-digesting) effects. Bromelain has been shown to be effective at thinning nasal secretions and provides an additional benefit of balancing inflammatory response. Berberine Sulfate Hydrate Berberine sulfate is a botanical extract found in the roots and barks of various plants including Oregon grape root, barberry and goldenseal. Berberine extract has been shown to support immune response by increasing blood flow to the spleen and by activating immune compounds such as macrophages. Berberine maintains healthy sinus function by quieting localized inflammatory response- Berberine has been shown to inhibit activator protein 1 (AP-1) and inhibits thromboxane A2 from platelets. Licorice Root Extract Licorice root has been used in Western and Eastern cultures for thousands of years. Licorice’s health-promoting benefits include soothing respiratory irritation.  The active components in licorice, glycyrrhizin and glycyrrhetinic acid, strengthen immune response by inducing interferon activity, activating macrophages and augmenting natural killer cell activity. Glycyrrhizin exerts its inflammatory balancing response by inhibiting the production of reacted oxygen species released by neutrophils. Andrographis Andrographis paniculata is a plant that has been used in Asian medicine for centuries. The immune boosting properties of andrographis have been research extensively in clinical studies- Per the analysis of seven double-blind controlled trials, andrographis has been shown to be a safe botanical for supporting upper respiratory tract health.   Eleuthero Recent studies utilizing the combination of Eleuthero and Andrographis have demonstrated the combination of herbs to be particularly helpful for patients with upper respiratory challenges.  Thyme Thyme has been traditionally used to help soothe sinuses and loosen phlegm.  Thymol, the active ingredient in thyme, also has immune supporting properties and competes with pathogens commonly found throughout the sinuses and respiratory tract. The German Commission E has approved thyme to help support respiratory challenges.