Lab - Dutch Hormone Testing - Dutch PLUS - Urinary Female Panel

$469.00 $625.00 -25% OFF

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Lab - Dutch Hormone Testing - Dutch PLUS - Urinary Female Panel

$469.00 $625.00 -25% OFF
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Description of Lab - Dutch Hormone Testing - Dutch PLUS - Urinary Female Panel

Please note: you MUST be a course member or full member of ours to order labs!!


NOW you can order directly through our Partners at RUPA HEALTH through our Conners Clinic LAB STORE - HERE

Through Rupa Health's Physician referral services, we can now recommend labs for people in nearly every state. They have a licensed professional in every state to sign-off on any/all lab orders.

Also, all labs are just 7% over doctor's cost making these a HUGE savings for patient/members!!!!!

See Conners Clinic's LAB STORE HERE



The DUTCH Plus is a comprehensive dried urine and saliva test that maximizes the available information from sex and adrenal hormone production and metabolism. With easy, at-home sample collection over the course of one day, providers can gain insights into the overall diurnal pattern of free cortisol and cortisone, along with the total distribution of cortisol metabolites.
This test offers further insight by including organic acid testing, which evaluates potential nutritional deficiencies, oxidative stress, gut dysbiosis, melatonin levels, and neuroinflammation.
With the DUTCH Plus, providers also get a closer look into adrenal function with details about a patient’s cortisol awakening response (CAR) by showing cortisol's natural rise and fall within the first hour of waking.

The results include:

• Analysis of 35 different hormones: estrogen, progesterone, testosterone, DHEA-S, and cortisol along with their metabolites, plus the cortisol awakening response (CAR) 

• Graphical representation of results and embedded video tutorials

• DUTCH OATs: 8-Hydroxy-2-deoxyguanosine (8-OHdG), melatonin (6-OHMS), and nine organic acid tests (VMA, HVA, KYNA, MMA, Xanthurenate, Pyroglutamate, Indican, b-Hydroxyisovalerate, Quinolinate)


Analytical and Clinical Validation

Precision Analytical’s testing methods go through a rigorous validation process to verify accuracy, recovery, and linearity. We pride ourselves in relentlessly pursuing the most accurate and precise techniques available for testing. See the data on the next page to support the analytical and clinical validation of this powerful new testing model.

The Easiest Patient Collection

Patients collect just four or five dried urine samples over a 24-hour period. Dried samples are stable for several weeks making them convenient to ship worldwide.

Effective HRT Monitoring

DUTCH testing was designed to be optimally effective for most forms of hormone replacement therapy. Unique methods are used for improved monitoring of oral progesterone and vaginal hormones.

DUTCH vs. Saliva Testing

While the free cortisol pattern in saliva has clinical value, there is a significant missing piece to surveying a patient’s HPA-Axis function with saliva testing – measuring cortisol metabolites. To properly characterize a patient’s cortisol status, free and metabolized cortisol should be measured to avoid misleading results when cortisol clearance is abnormally high or low. Likewise with sex hormones, measuring estrogen and androgen metabolites gives a fuller picture for more precise clinical diagnosis of hormonal imbalances and HRT monitoring.

DUTCH vs. Serum Testing

While the most universally accepted testing method (due to the availability of FDA-cleared analyzers that are reliable and inexpensive), serum testing is lacking in some areas. Adrenal hormones cannot be effectively tested in serum because free cortisol cannot be tested throughout the day. There is also a lack of extensive metabolite testing (especially for cortisol and estrogens).

DUTCH vs. 24-Hour Urine Testing

There are two primary drawbacks to 24-hour urine testing of hormones. First, the collection is cumbersome, and as many as 40% of those who collect, do so in error (Tanaka, 2002). Secondly, dysfunction in the diurnal pattern of cortisol cannot be ascertained from a 24-hour collection. Some providers add saliva for daily free cortisol. DUTCH eliminates the need for two tests.

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{"id":3551059705920,"title":"Lab - Dutch Hormone Testing - Dutch PLUS - Urinary Female Panel","handle":"lab-dutch-hormone-testing-dutch-panel-urinary-female-panel","description":"\u003ch1\u003e\u003cspan style=\"color: #ff2a00;\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003ePlease note: you MUST be a course member or full member of ours to order labs!!\u003c\/strong\u003e\u003c\/span\u003e\u003c\/h1\u003e\n\u003ch1\u003e\n\u003cspan style=\"color: #ff2a00;\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003e\u003c\/strong\u003e\u003c\/span\u003e\u003cbr\u003e\n\u003c\/h1\u003e\n\u003ch1\u003e\u003cstrong data-mce-fragment=\"1\"\u003eNOW you can order directly through our Partners at RUPA HEALTH through our Conners Clinic LAB STORE - \u003ca href=\"https:\/\/labs.rupahealth.com\/store\/storefront_N7KqK4X\" data-mce-href=\"https:\/\/labs.rupahealth.com\/store\/storefront_N7KqK4X\" target=\"_blank\"\u003eHERE\u003c\/a\u003e\u003c\/strong\u003e\u003c\/h1\u003e\n\u003ch3 data-mce-fragment=\"1\"\u003e\n\u003cstrong data-mce-fragment=\"1\"\u003e\u003c\/strong\u003eThrough Rupa Health's Physician referral services, we can now recommend labs for people in nearly every state. They have a licensed professional in every state to sign-off on any\/all lab orders.\u003c\/h3\u003e\n\u003ch3\u003eAlso, all labs are just 7% over doctor's cost making these a HUGE savings for patient\/members!!!!!\u003c\/h3\u003e\n\u003ch2 data-mce-fragment=\"1\"\u003e\u003ca href=\"https:\/\/labs.rupahealth.com\/store\/storefront_N7KqK4X\" data-mce-href=\"https:\/\/labs.rupahealth.com\/store\/storefront_N7KqK4X\" target=\"_blank\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eSee Conners Clinic's LAB STORE HERE\u003c\/strong\u003e\u003c\/a\u003e\u003c\/h2\u003e\n\u003cdiv data-node=\"5b8ec2e062528\" class=\"fl-module fl-module-rich-text fl-node-5b8ec2e062528\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv data-node=\"5b8ec2e062528\" class=\"fl-module fl-module-rich-text fl-node-5b8ec2e062528\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv class=\"fl-module-content fl-node-content\"\u003e\n\u003cmeta charset=\"utf-8\"\u003e\n\u003cmeta charset=\"utf-8\"\u003e\n\u003cspan\u003eThe DUTCH Plus is a comprehensive dried urine and saliva test that maximizes the available information from sex and adrenal hormone production and metabolism. With easy, at-home sample collection over the course of one day, providers can gain insights into the overall diurnal pattern of free cortisol and cortisone, along with the total distribution of cortisol metabolites. \u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"fl-module-content fl-node-content\"\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/div\u003e\n\u003cdiv class=\"fl-module-content fl-node-content\"\u003e\n\u003cspan\u003eThis test offers further insight by including organic acid testing, which evaluates potential nutritional deficiencies, oxidative stress, gut dysbiosis, melatonin levels, and neuroinflammation.\u003c\/span\u003e\u003cbr\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"fl-module-content fl-node-content\"\u003e\u003c\/div\u003e\n\u003cdiv class=\"fl-module-content fl-node-content\"\u003e\n\u003cmeta charset=\"utf-8\"\u003e\n\u003cspan\u003eWith the DUTCH Plus, providers also get a closer look into adrenal function with details about a patient’s cortisol awakening response (CAR) by showing cortisol's natural rise and fall within the first hour of waking.\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"fl-module-content fl-node-content\"\u003e\n\u003cspan\u003e\u003c\/span\u003e\u003cbr\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"fl-module-content fl-node-content\"\u003e\u003cstrong\u003eThe results include:\u003c\/strong\u003e\u003c\/div\u003e\n\u003cdiv class=\"fl-module-content fl-node-content\"\u003e\n\u003cspan\u003e\u003c\/span\u003e\u003cbr\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"fl-module-content fl-node-content\"\u003e\u003cspan\u003e• Analysis of 35 different hormones: estrogen, progesterone, testosterone, DHEA-S, and cortisol along with their metabolites, plus the cortisol awakening response (CAR) \u003c\/span\u003e\u003c\/div\u003e\n\u003cdiv class=\"fl-module-content fl-node-content\"\u003e\n\u003cspan\u003e\u003c\/span\u003e\u003cbr\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"fl-module-content fl-node-content\"\u003e\u003cspan\u003e• Graphical representation of results and embedded video tutorials \u003c\/span\u003e\u003c\/div\u003e\n\u003cdiv class=\"fl-module-content fl-node-content\"\u003e\n\u003cspan\u003e\u003c\/span\u003e\u003cbr\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"fl-module-content fl-node-content\"\u003e\u003cspan\u003e• DUTCH OATs: 8-Hydroxy-2-deoxyguanosine (8-OHdG), melatonin (6-OHMS), and nine organic acid tests (VMA, HVA, KYNA, MMA, Xanthurenate, Pyroglutamate, Indican, b-Hydroxyisovalerate, Quinolinate)\u003c\/span\u003e\u003c\/div\u003e\n\u003cdiv class=\"fl-module-content fl-node-content\"\u003e\n\u003cb\u003e\u003c\/b\u003e\u003cbr\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"fl-module-content fl-node-content\"\u003e\u003cb\u003e\u003ciframe title=\"DUTCH Plus® Report Overview\" src=\"https:\/\/www.youtube.com\/embed\/UvboBV0zHc4\" height=\"534\" width=\"950\" allowfullscreen=\"\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture\" frameborder=\"0\"\u003e\u003c\/iframe\u003e\u003c\/b\u003e\u003c\/div\u003e\n\u003cdiv class=\"fl-module-content fl-node-content\"\u003e\n\u003cb\u003e\u003c\/b\u003e\u003cbr\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"fl-module-content fl-node-content\"\u003e\u003cb\u003eAnalytical and Clinical Validation\u003c\/b\u003e\u003c\/div\u003e\n\u003cdiv class=\"fl-module-content fl-node-content\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv class=\"fl-module-content fl-node-content\"\u003ePrecision Analytical’s testing methods go through a rigorous validation process to verify accuracy, recovery, and linearity. We pride ourselves in relentlessly pursuing the most accurate and precise techniques available for testing. See the data on the next page to support the analytical and clinical validation of this powerful new testing \u003cspan class=\"s1\"\u003emodel.\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"fl-module-content fl-node-content\"\u003e\u003cspan class=\"s1\"\u003e\u003c\/span\u003e\u003c\/div\u003e\n\u003cdiv data-node=\"5b8ec237b7ce1\" class=\"fl-module fl-module-rich-text fl-node-5b8ec237b7ce1\"\u003e\n\u003cdiv class=\"fl-module-content fl-node-content\"\u003e\n\u003cdiv class=\"fl-rich-text\"\u003e\n\u003cp class=\"p1\"\u003e\u003cb\u003eThe Easiest Patient Collection\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003ePatients collect just four or five dried urine samples over a 24-hour period. Dried samples are stable for several weeks making them convenient to ship \u003cspan class=\"s1\"\u003eworldwide. \u003c\/span\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv data-node=\"5b8ec326c7f82\" class=\"fl-module fl-module-rich-text fl-node-5b8ec326c7f82\"\u003e\n\u003cdiv class=\"fl-module-content fl-node-content\"\u003e\n\u003cdiv class=\"fl-rich-text\"\u003e\n\u003cp class=\"p1\"\u003e\u003cb\u003eEffective HRT Monitoring\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan class=\"s1\"\u003eDUTCH testing was designed to \u003c\/span\u003ebe optimally effective for most forms of hormone replacement therapy. Unique methods are used for improved monitoring of oral progesterone and vaginal hormones.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDUTCH vs. Saliva Testing\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eWhile the free cortisol pattern in saliva has clinical value, there is a significant missing piece to surveying a patient’s HPA-Axis function with saliva testing – measuring cortisol metabolites. To properly characterize a patient’s cortisol status, free and metabolized cortisol should be measured to avoid misleading results when cortisol clearance is abnormally high or low. Likewise with sex hormones, measuring estrogen and androgen metabolites gives a fuller picture for more precise clinical diagnosis of hormonal imbalances and HRT monitoring.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDUTCH vs. Serum Testing\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eWhile the most universally accepted testing method (due to the availability of FDA-cleared analyzers that are reliable and inexpensive), serum testing is lacking in some areas. Adrenal hormones cannot be effectively tested in serum because free cortisol cannot be tested throughout the day. There is also a lack of extensive metabolite testing (especially for cortisol and estrogens).\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDUTCH vs. 24-Hour Urine Testing\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThere are two primary drawbacks to 24-hour urine testing of hormones. First, the collection is cumbersome, and as many as 40% of those who collect, do so in error (Tanaka, 2002). Secondly, dysfunction in the diurnal pattern of cortisol cannot be ascertained from a 24-hour collection. Some providers add saliva for daily free cortisol. DUTCH eliminates the need for two tests.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","published_at":"2020-05-21T16:38:05-05:00","created_at":"2019-04-23T12:25:24-05:00","vendor":"Conners Clinic Labs","type":"Lab Test Kit","tags":["Cancer","Men","Women"],"price":46900,"price_min":46900,"price_max":46900,"available":true,"price_varies":false,"compare_at_price":62500,"compare_at_price_min":62500,"compare_at_price_max":62500,"compare_at_price_varies":false,"variants":[{"id":28159893831744,"title":"Default Title","option1":"Default Title","option2":null,"option3":null,"sku":"210000001109","requires_shipping":true,"taxable":true,"featured_image":null,"available":true,"name":"Lab - Dutch Hormone Testing - Dutch PLUS - Urinary Female Panel","public_title":null,"options":["Default Title"],"price":46900,"weight":170,"compare_at_price":62500,"inventory_management":"shopify","barcode":"","requires_selling_plan":false,"selling_plan_allocations":[],"quantity_rule":{"min":1,"max":null,"increment":1}}],"images":["\/\/shop.connersclinic.com\/cdn\/shop\/products\/lab-dutch-hormone-testing-dutch-panel-urinary-female-panel-conners-clinic-conners-clinic-11015976878144.png?v=1729200684","\/\/shop.connersclinic.com\/cdn\/shop\/products\/lab-dutch-hormone-testing-dutch-panel-urinary-female-panel-conners-clinic-conners-clinic-11015976976448.jpg?v=1625836852","\/\/shop.connersclinic.com\/cdn\/shop\/files\/lab-dutch-hormone-testing-dutch-plus-urinary-female-panel-conners-clinic-conners-clinic-40562291179740.png?v=1715621149"],"featured_image":"\/\/shop.connersclinic.com\/cdn\/shop\/products\/lab-dutch-hormone-testing-dutch-panel-urinary-female-panel-conners-clinic-conners-clinic-11015976878144.png?v=1729200684","options":["Title"],"media":[{"alt":"Lab - Dutch Hormone Testing- Dutch Panel- Urinary Female Panel Conners Clinic Lab Test Kit - Conners Clinic","id":22089997090982,"position":1,"preview_image":{"aspect_ratio":1.0,"height":560,"width":560,"src":"\/\/shop.connersclinic.com\/cdn\/shop\/products\/lab-dutch-hormone-testing-dutch-panel-urinary-female-panel-conners-clinic-conners-clinic-11015976878144.png?v=1729200684"},"aspect_ratio":1.0,"height":560,"media_type":"image","src":"\/\/shop.connersclinic.com\/cdn\/shop\/products\/lab-dutch-hormone-testing-dutch-panel-urinary-female-panel-conners-clinic-conners-clinic-11015976878144.png?v=1729200684","width":560},{"alt":"Lab - Dutch Hormone Testing- Dutch Panel- Urinary Female Panel Conners Clinic Lab Test Kit - Conners Clinic","id":22065391960230,"position":2,"preview_image":{"aspect_ratio":2.267,"height":375,"width":850,"src":"\/\/shop.connersclinic.com\/cdn\/shop\/products\/lab-dutch-hormone-testing-dutch-panel-urinary-female-panel-conners-clinic-conners-clinic-11015976976448.jpg?v=1625836852"},"aspect_ratio":2.267,"height":375,"media_type":"image","src":"\/\/shop.connersclinic.com\/cdn\/shop\/products\/lab-dutch-hormone-testing-dutch-panel-urinary-female-panel-conners-clinic-conners-clinic-11015976976448.jpg?v=1625836852","width":850},{"alt":"Lab - Dutch Hormone Testing - Dutch PLUS - Urinary Female Panel Conners Clinic Lab Test Kit - Conners Clinic","id":33229686833372,"position":3,"preview_image":{"aspect_ratio":0.653,"height":1344,"width":878,"src":"\/\/shop.connersclinic.com\/cdn\/shop\/files\/lab-dutch-hormone-testing-dutch-plus-urinary-female-panel-conners-clinic-conners-clinic-40562291179740.png?v=1715621149"},"aspect_ratio":0.653,"height":1344,"media_type":"image","src":"\/\/shop.connersclinic.com\/cdn\/shop\/files\/lab-dutch-hormone-testing-dutch-plus-urinary-female-panel-conners-clinic-conners-clinic-40562291179740.png?v=1715621149","width":878}],"requires_selling_plan":false,"selling_plan_groups":[],"content":"\u003ch1\u003e\u003cspan style=\"color: #ff2a00;\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003ePlease note: you MUST be a course member or full member of ours to order labs!!\u003c\/strong\u003e\u003c\/span\u003e\u003c\/h1\u003e\n\u003ch1\u003e\n\u003cspan style=\"color: #ff2a00;\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003e\u003c\/strong\u003e\u003c\/span\u003e\u003cbr\u003e\n\u003c\/h1\u003e\n\u003ch1\u003e\u003cstrong data-mce-fragment=\"1\"\u003eNOW you can order directly through our Partners at RUPA HEALTH through our Conners Clinic LAB STORE - \u003ca href=\"https:\/\/labs.rupahealth.com\/store\/storefront_N7KqK4X\" data-mce-href=\"https:\/\/labs.rupahealth.com\/store\/storefront_N7KqK4X\" target=\"_blank\"\u003eHERE\u003c\/a\u003e\u003c\/strong\u003e\u003c\/h1\u003e\n\u003ch3 data-mce-fragment=\"1\"\u003e\n\u003cstrong data-mce-fragment=\"1\"\u003e\u003c\/strong\u003eThrough Rupa Health's Physician referral services, we can now recommend labs for people in nearly every state. They have a licensed professional in every state to sign-off on any\/all lab orders.\u003c\/h3\u003e\n\u003ch3\u003eAlso, all labs are just 7% over doctor's cost making these a HUGE savings for patient\/members!!!!!\u003c\/h3\u003e\n\u003ch2 data-mce-fragment=\"1\"\u003e\u003ca href=\"https:\/\/labs.rupahealth.com\/store\/storefront_N7KqK4X\" data-mce-href=\"https:\/\/labs.rupahealth.com\/store\/storefront_N7KqK4X\" target=\"_blank\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eSee Conners Clinic's LAB STORE HERE\u003c\/strong\u003e\u003c\/a\u003e\u003c\/h2\u003e\n\u003cdiv data-node=\"5b8ec2e062528\" class=\"fl-module fl-module-rich-text fl-node-5b8ec2e062528\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv data-node=\"5b8ec2e062528\" class=\"fl-module fl-module-rich-text fl-node-5b8ec2e062528\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv class=\"fl-module-content fl-node-content\"\u003e\n\u003cmeta charset=\"utf-8\"\u003e\n\u003cmeta charset=\"utf-8\"\u003e\n\u003cspan\u003eThe DUTCH Plus is a comprehensive dried urine and saliva test that maximizes the available information from sex and adrenal hormone production and metabolism. With easy, at-home sample collection over the course of one day, providers can gain insights into the overall diurnal pattern of free cortisol and cortisone, along with the total distribution of cortisol metabolites. \u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"fl-module-content fl-node-content\"\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/div\u003e\n\u003cdiv class=\"fl-module-content fl-node-content\"\u003e\n\u003cspan\u003eThis test offers further insight by including organic acid testing, which evaluates potential nutritional deficiencies, oxidative stress, gut dysbiosis, melatonin levels, and neuroinflammation.\u003c\/span\u003e\u003cbr\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"fl-module-content fl-node-content\"\u003e\u003c\/div\u003e\n\u003cdiv class=\"fl-module-content fl-node-content\"\u003e\n\u003cmeta charset=\"utf-8\"\u003e\n\u003cspan\u003eWith the DUTCH Plus, providers also get a closer look into adrenal function with details about a patient’s cortisol awakening response (CAR) by showing cortisol's natural rise and fall within the first hour of waking.\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"fl-module-content fl-node-content\"\u003e\n\u003cspan\u003e\u003c\/span\u003e\u003cbr\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"fl-module-content fl-node-content\"\u003e\u003cstrong\u003eThe results include:\u003c\/strong\u003e\u003c\/div\u003e\n\u003cdiv class=\"fl-module-content fl-node-content\"\u003e\n\u003cspan\u003e\u003c\/span\u003e\u003cbr\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"fl-module-content fl-node-content\"\u003e\u003cspan\u003e• Analysis of 35 different hormones: estrogen, progesterone, testosterone, DHEA-S, and cortisol along with their metabolites, plus the cortisol awakening response (CAR) \u003c\/span\u003e\u003c\/div\u003e\n\u003cdiv class=\"fl-module-content fl-node-content\"\u003e\n\u003cspan\u003e\u003c\/span\u003e\u003cbr\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"fl-module-content fl-node-content\"\u003e\u003cspan\u003e• Graphical representation of results and embedded video tutorials \u003c\/span\u003e\u003c\/div\u003e\n\u003cdiv class=\"fl-module-content fl-node-content\"\u003e\n\u003cspan\u003e\u003c\/span\u003e\u003cbr\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"fl-module-content fl-node-content\"\u003e\u003cspan\u003e• DUTCH OATs: 8-Hydroxy-2-deoxyguanosine (8-OHdG), melatonin (6-OHMS), and nine organic acid tests (VMA, HVA, KYNA, MMA, Xanthurenate, Pyroglutamate, Indican, b-Hydroxyisovalerate, Quinolinate)\u003c\/span\u003e\u003c\/div\u003e\n\u003cdiv class=\"fl-module-content fl-node-content\"\u003e\n\u003cb\u003e\u003c\/b\u003e\u003cbr\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"fl-module-content fl-node-content\"\u003e\u003cb\u003e\u003ciframe title=\"DUTCH Plus® Report Overview\" src=\"https:\/\/www.youtube.com\/embed\/UvboBV0zHc4\" height=\"534\" width=\"950\" allowfullscreen=\"\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture\" frameborder=\"0\"\u003e\u003c\/iframe\u003e\u003c\/b\u003e\u003c\/div\u003e\n\u003cdiv class=\"fl-module-content fl-node-content\"\u003e\n\u003cb\u003e\u003c\/b\u003e\u003cbr\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"fl-module-content fl-node-content\"\u003e\u003cb\u003eAnalytical and Clinical Validation\u003c\/b\u003e\u003c\/div\u003e\n\u003cdiv class=\"fl-module-content fl-node-content\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv class=\"fl-module-content fl-node-content\"\u003ePrecision Analytical’s testing methods go through a rigorous validation process to verify accuracy, recovery, and linearity. We pride ourselves in relentlessly pursuing the most accurate and precise techniques available for testing. See the data on the next page to support the analytical and clinical validation of this powerful new testing \u003cspan class=\"s1\"\u003emodel.\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"fl-module-content fl-node-content\"\u003e\u003cspan class=\"s1\"\u003e\u003c\/span\u003e\u003c\/div\u003e\n\u003cdiv data-node=\"5b8ec237b7ce1\" class=\"fl-module fl-module-rich-text fl-node-5b8ec237b7ce1\"\u003e\n\u003cdiv class=\"fl-module-content fl-node-content\"\u003e\n\u003cdiv class=\"fl-rich-text\"\u003e\n\u003cp class=\"p1\"\u003e\u003cb\u003eThe Easiest Patient Collection\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003ePatients collect just four or five dried urine samples over a 24-hour period. Dried samples are stable for several weeks making them convenient to ship \u003cspan class=\"s1\"\u003eworldwide. \u003c\/span\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv data-node=\"5b8ec326c7f82\" class=\"fl-module fl-module-rich-text fl-node-5b8ec326c7f82\"\u003e\n\u003cdiv class=\"fl-module-content fl-node-content\"\u003e\n\u003cdiv class=\"fl-rich-text\"\u003e\n\u003cp class=\"p1\"\u003e\u003cb\u003eEffective HRT Monitoring\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan class=\"s1\"\u003eDUTCH testing was designed to \u003c\/span\u003ebe optimally effective for most forms of hormone replacement therapy. Unique methods are used for improved monitoring of oral progesterone and vaginal hormones.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDUTCH vs. Saliva Testing\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eWhile the free cortisol pattern in saliva has clinical value, there is a significant missing piece to surveying a patient’s HPA-Axis function with saliva testing – measuring cortisol metabolites. To properly characterize a patient’s cortisol status, free and metabolized cortisol should be measured to avoid misleading results when cortisol clearance is abnormally high or low. Likewise with sex hormones, measuring estrogen and androgen metabolites gives a fuller picture for more precise clinical diagnosis of hormonal imbalances and HRT monitoring.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDUTCH vs. Serum Testing\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eWhile the most universally accepted testing method (due to the availability of FDA-cleared analyzers that are reliable and inexpensive), serum testing is lacking in some areas. Adrenal hormones cannot be effectively tested in serum because free cortisol cannot be tested throughout the day. There is also a lack of extensive metabolite testing (especially for cortisol and estrogens).\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDUTCH vs. 24-Hour Urine Testing\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThere are two primary drawbacks to 24-hour urine testing of hormones. First, the collection is cumbersome, and as many as 40% of those who collect, do so in error (Tanaka, 2002). Secondly, dysfunction in the diurnal pattern of cortisol cannot be ascertained from a 24-hour collection. Some providers add saliva for daily free cortisol. DUTCH eliminates the need for two tests.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e"}

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