Dual Phase Optimizers to Support Phase I & II Detox
Dual Phase Detox is designed to support balanced activity of the body’s Phase I and Phase II detoxification processes.* It has been formulated to contain select ingredients, Dual Phase Optimizers (DPO), to enhance the activities of hepatic detoxification enzymes and support healthy detoxification pathways.
The 5-MTHF in this formula – Quatrefolic® – is the most biologically active form of folate, allowing rapid uptake into the bloodstream.* The 5-MTHF in this formula is also known as the "L" form of 5-MTHF since it is the reduced form of folate.
Dual Phase Detox features ingredients that work solely to enhance Phase II detoxification and support the excretion of toxins from the body.* For example, during the process of sulfation, toxins are neutralized through the addition of a sulfate.
Therefore, sulfur-containing substances such as sodium sulfate, methylsulfonylmethane (MSM), and NAC are effective detoxifiers. Ellagic acid (from pomegranate), Calcium D-Glucarate, watercress, alpha lipoic acid, and catechins from green tea leaf extract, also stimulate Phase II detoxification pathways.
Calcium D-Glucarate improves the metabolism of toxins due to its ability to increase glucuronidation. Through this process, glucuronic acid is added to a substance, yielding compounds called glucuronides. These end products are more water soluble than their parent compounds, facilitating their elimination from the body. Many xenobiotic substances — such as drugs, pollutants, and hormones — are processed through glucuronidation.
Animal research indicates calcium d-glucarate protects tissues against excessive estrogen exposure through enhancing glucuronidation. Finally, Dual Phase Detox incorporates antioxidants to help quench any free radicals released during the first phase of detoxification, such as artichoke leaf extract and alpha lipoic acid. Artichoke also helps increase bile secretion and urine output, both of which enhance the excretion of toxins.
NOTE: All of the above statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
