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*This item may take extra time to ship* Cardiovascular Support* HIGH OMEGA-3™ FISH OIL contains over 1000mg of Omega-3 fatty acids that are essential for good nutrition and overall wellness. * Studies have shown that the health benefits of fish oil include its ability to support various heart conditions and supports the management of cholesterol levels already within the normal range. * Fish oil supports a positive mood, strengthens the immune system and supports healthy muscles and joints. It also supports healthy weight loss and overall skin care.

Item Description: Male Libido Support HisSynergy™ provides premium Ayurvedic herbal extract support for healthy male sexual function, libido, and vitality—in one formula. Gluten Free Vegetarian Non-GMO

NEW: Now in NEW packaging Conners Clinic Originals Hista Clear is a patented enzyme formula containing diamine oxidase (DAO) - the main enzyme responsible for the degradation of ingested histamine.  This enzyme has been clinically tested and found to break down food-derived histamine in the digestive tract.   Our bodies are complex, and there is usually more at play than we think. What most don’t take into consideration when addressing histamine-related health issues is genetics. Whether you’re on a low histamine diet due to histamine intolerance, or simply trying to reduce high histamine foods for general health, you will benefit from understanding how your genes are related. Learn more about histamine and genetics here! Our body has two distinct methods of clearing things that could bring it harm: our immune system kills living toxins (bacteria, virus, parasites…) and our detoxification pathways clear non-living toxins (chemicals, heavy metals, drugs…). We have one other system that sits somewhere in the middle between the immune and the detoxification systems that helps with both: the mast cells. Read more about Histamine’s Double-edge Sword in the Formation and Progression of Cancer.   Clinical Applications Supports Healthy Degradation of Food-Derived Histamine* Enhances the Presence of Diamine Oxidase in the Digestive Tract* Description: Hista Clear provides a concentrated source of diamine oxidase (DAO)—the main enzyme responsible for the degradation of ingested histamine. This formula delivers the clinically researched dose of DAO in an easy-to-swallow, gastro-resistant mini-tablet, which is essential for releasing DAO in the small intestine, where it breaks down food-derived histamine. HistDAO does not manage or address antibody-related or IgE-related food allergies.* Discussion: Histamine is a bioactive or “vasoactive” amine produced in the body in response to an injury or foreign substance. It has an array of physiological effects, including increasing blood supply to specific sites in the body. In addition, histamine is involved in the immune response, regulation of gastric acid, permeability of blood vessels, contraction of muscles, and the normal response to inflammation.[1] The highest concentrations of histamine in the body are found in the gastrointestinal tract, lungs, and skin, with lesser amounts in the brain and heart.* Histamine is not only produced in the body but is also present in many fermented foods, such as sauerkraut, sausage, cheese, yogurt, and alcoholic beverages. Tuna, olives, spinach, eggplant, avocados, tomatoes, cherries, and citrus fruits are other histamine-containing foods. Despite their absence of histamine, some foods, such as berries, tea, and a variety of spices, stimulate the endogenous production of the amine due to their benzoate content. In addition, microbial fermentation can convert the histidine in high-protein foods to histamine so that the histamine content of food can increase over time.*[1] Endogenous and exogenous histamine must be broken down in order to maintain homeostasis and histamine balance. The enzyme diamine oxidase (DAO) degrades histamine by converting it from 2-(4-imidazolyl)- ethylamine to the inactive metabolite imidazole acetaldehyde.[2] The active ingredient in HistaClear is porcine-derived diamine oxidase, and research suggests that DAO derived from porcine kidney appears to have identical action to DAO derived from porcine intestine.[3] In humans and other mammals, DAO is found in high concentrations in the gastrointestinal mucosa. Animal studies suggest that circulating DAO may be a marker for mucosal integrity and maturity.[4] Certain drugs may affect histamine balance in the body by promoting histamine release or inhibiting DAO.*[2] Histamine tolerance may not be the same for everyone. Results of a double-blind, placebo-controlled crossover study suggest that tolerance to histamine can vary from individual to individual.[5] Total body histamine load must be considered when evaluating histamine tolerance, and a balance between histamine and DAO appears to be crucial to maintaining skin, rhinoconjunctival, and gastrointestinal health.[2,6] Genetic and environmental factors may interact to influence DAO expression. Ongoing research addresses the role that genetic variations may play in individual differences in DAO metabolism, and serum activity was significantly associated with seven single nucleotide variations within the DAO gene.[7,8] Histamine tolerance may be reflected in detailed questionnaires, food intake logs, trial with low-histamine diet, and measurement of DAO and histamine.*[9,10] Histamine tolerance and its manifestation may vary from organ to organ as well. A study of 39 patients suggested that intake of DAO produced a statistically significant reduction in symptoms associated with exogenous histamine ingestion, although single symptoms were not found to be reproducible.*[11] Ultimately, diminished serum DAO levels appear to be associated with changes in histamine degradation and serum histamine levels.[10] Although the mechanism of histamine degradation is uniform throughout the body, HistaClear only addresses excess exogenous histamine found in the folds, villi, and microvilli of the small intestine. HistaClear is not absorbed and therefore does not have systemic activity. A two-capsule dose of HistaClear contains 20 mg of vitamin C and 20,000 HDU (histamine degrading units) from diamine oxidase. HistaClear is NOT EFFECTIVE for symptoms of immune- related food allergies, such as peanuts, shellfish, etc.* Read our article: Low Histamine Diet: The High Histamine Foods List Genetic supplementation is complex and requires a deep understanding of the entire genetic picture.  Our Genetics Membership includes the kit, a full workup, review, report, summary, Dr. Conners’ personalized recommendations - and MORE.  Click HERE for details. Video: Directions: Take 1-2 capsules no more than 15 minutes before the consumption of histamine-rich foods, or take as directed by your healthcare practitioner. Cautions: Consult your healthcare practitioner before use, especially if you are pregnant or nursing. Keep out of reach of children. Avoid if allergic to pork or any other ingredient. HistaClear is NOT EFFECTIVE for symptoms of immune- related food allergies, such as peanuts, shellfish, etc. Your browser does not support the video tag.

This may be fulfilled by a product that this manufacturer Private Labels for us When you’re choosing to decrease the levels of histamine in your diet, it’s just that: decreasing. It is simply impossible (and actually unnecessary) to try to eliminate histamines. They’re everywhere. However what you can do, and should focus on, is reducing your intake of high histamine foods along with combining foods that are low in histamine with other foods can help break down and clear histamine from the body. Use this list to help lower your histamine load. Using products like our Histamine Scavenger can greatly reduce one's symptoms of excess histamine. This is one of our BEST selling products with the number of people RE-purchasing at the highest - meaning...it WORKS! On SALE this month - $3.00 off per bottle!!!! Ingredients: Larch Tree Fiber Pine Bark Extract Aloe Vera Leaf Quercetin Bromelain Nettle Leaf Marshmallow Root Bitter Orange Licorice Sugar free, salt free, starch free, preservative free, no artificial colors or flavors or additives, wheat free, soy free, yeast free, no milk derivatives Potential Benefits: Supports normal histamine levels Reduce inflammatory responses to non-allergen exposures Can help the body repair leaky gut, or prevent its onset Supports ABP1 & HNMT gene pathways Description: Histamine is a versatile, yet unique, compound that naturally interacts with several physiological pathways. Typically, bodily injury and antigen exposure promotes the release of histamine. A white blood cell variation known as a basophil and similarly constructed mast cells, found in connective tissue, are the main producers of histamine. Despite various origins and locations, histamine compounds found outside of the CNS contribute to a universal goal: initiating an inflammatory response. Histamine, as a result of corresponding neural receptors, has the potential for profound effects on the hypothalamus and other neurotransmitters: specifically effecting appetite and sleep patterns. Therefore, increased histamine can disrupt usual compound levels in the CNS.  Secreted histamine also promotes vasodilation, blood plasma release from adjacent blood vessels, and stimulates gastric acid production. Vasodilation allows for greater capillary permeability; therefore, white blood cells are capable of contacting pathogens found in interstitial fluid, also potentially effecting intestinal permeability.  Excessive histamine can be correlated to genetic mutations, leaky gut, allergies, and an individual’s diet. Studies have suggested gliadin, a protein found in wheat, to be involved with mast cell function and secretion of histamine; similarly, gliadin also stimulates the release of Zonulin. Under further observation, Zonulin has been found, during an ex vivo study, to increase intestinal permeability, serving as another contributor to a leaky gut.  Genetic mutations found in the ABP1 and HNMT genes are potential indicators for elevated histamine. Furthermore, increased histamine levels can result in heart palpitations, low blood pressure, hypertension, fatigue, anxiety, joint pain, irritable bowel syndrome, stomach ulcers, adrenal gland fatigue, and altered sleep patterns. Histamine Scavenger contains the essential ingredients believed to promote the reduction of harmful histamine accumulation.   Genetic supplementation is complex and requires a deep understanding of the entire genetic picture.  Our Genetics Membership includes the kit, a full workup, review, report, summary, Dr. Conners’ personalized recommendations - and MORE.  Click HERE for details. Histamine Scavenger is designed to reduce histamine (an inflammatory chemical) in the tissues. Clear Histamine Scavenger

Clinical Applications: May help support healthy mucous membranes* May help support seasonal comfort* May help support immune health* Description: HistaminX by Seeking Health provides a combination of supportive herbal and plantderived compounds that may work together to support seasonal comfort. Dietary changes and environmental factors are thought to contribute to the increase in allergies seen over recent years. Increased consumption of a "Western diet" including fewer fruits and vegetables and more processed grains, fats and meats leads to a significant decrease in dietary intakes of beneficial compounds such as flavonoids, antioxidants, and polyphenols found in fresh fruits and vegetables.* *This item may take longer to ship out*    

Comprehensive Mast Cell Support* HistaQuel® is a comprehensive formula providing a multi-faceted, systemic approach to supporting healthy mast cell function and histamine response.* What is a mast cell? Mast cells are part of the immune system and are primarily responsible for generating and releasing histamine in the body. Under typical conditions, this is a natural function of a healthy body working to rid itself of an allergen. However, mast cells can become overactive, releasing a cascade of histamine throughout the body, which results in heightened or continuous allergy symptoms. Many allergy support supplements, such as diamine oxidase (DAO), focus on reducing histamine within the gut by utilizing enzymes to degrade the histamine. Unfortunately, this means they are limited in their function and only effective for reducing ingested histamine (i.e., histamine introduced to the body through the food we eat) within the GI tract. However, mast cells release histamine systemically. Therefore, when mast cells are activated, they release histamine throughout the body. Enzymes such as DAO do nothing to address the healthy function of mast cells or support the body’s healthy response to histamine and therefore serve limited benefit. How does HistaQuel® support mast cell health? HistaQuel® utilizes a comprehensive approach to support healthy mast cell function and histamine response systemically.* Seven clinically researched flavonoids and herbs have been combined to promote healthy levels of histamine production and healthy levels of histamine absorption.* This holistic approach resulted in a comprehensive formula featuring dual mechanisms of action. Dual Mechanisms of Action Promotes healthy amount of histamine release by supporting healthy mast cell function* Supports healthy level of histamine absorption by blocking histamine receptors (via competitive inhibition)*

OUT OF STOCK Supports Healthy Degradation of Food-Derived Histamine*   Clinical Applications Supports Healthy Degradation of Food-Derived Histamine* Enhances the Presence of Diamine Oxidase in the Digestive Tract* Description:  HistoDAO™ is a patented enzyme formula containing diamine oxidase (DAO)—the main enzyme responsible for the degradation of ingested histamine. This enzyme has been clinically tested and found to break down food-derived histamine in the digestive tract. DAO is not absorbed and does not have systemic activity. HistDAO does not manage or address antibody-related or IgE-related food allergies.*  

This product is on our Fire Sale of expired/soon to be expired products. But rest assured, they are still as potent for at least another 12-24 months! HistoPlex® supplies a proprietary blend of herbal extracts shown to possess immunomodulating properties. A variety of botanical preparations have been reported as useful nutritional adjuncts to aide in normalizing immune processes.

This product is on our Fire Sale of expired/soon to be expired products. But rest assured, they are still as potent for at least another 12-24 months! Comprehensive Heavy Metal Protection* HM Protect™ is an exceptional formulation of antioxidants, minerals and nutrients designed to support a healthy response to environmental heavy metal toxicity.* Key ingredients have been included for their role in supporting the metabolism and detoxification of heavy metals.* Cilantro and chlorella support the body's normal processes for responding to environmental heavy metal exposure.*  Zinc aids in supporting kidney function by increasing the production of cysteine-rich metallothionein proteins.* N-Acetyl L-Cysteine (NAC) is a unique form of the amino acid l-cysteine which has been found to support healthy tissue levels of glutathione (GSH).*

HM-ET Binder supports the body’s natural ability to detoxify and encourages cellular repair.* With the addition of Carbon Technology, it lends increased support to mitochondrial health, immunity, energy production, and long-term health.*HM-ET Binder is primarily designed for clients who are in the intermediate stages of promoting detoxification.* Because of this, HM-ET Binder is typically recommended after a client has already introduced BioToxin Binder and ViRadChem Binder to their routine.Formulated with Carbon Technology Carbon Technology is a proprietary blend of fulvic acids and polysaccharides that support cellular repair and the body’s natural ability to detoxify.* With a low pH, Carbon Technology also helps protect ingredients from being digested by stomach acid, so that they remain intact as they enter the desired location in the body.

HM-ND (Detox-ND), by Premier Research Labs, offers a micro-cultured, vegan, fermented botanical formula for full body detoxification. Ingredients Organic Chlorella Organic Cillantro Organic Parsley Does Not Contain Added stearates. Potential Benefits supports healthy detoxification improves function of detox organs Discussion Detox-ND also known as HM-ND™ is made by using our unique probiotic-fermented technology that creates solubilized, bioavailable nutrients as well as their respective biochemical profiles. HM-ND™ features three fermented, organic greens (organic chlorella, organic cilantro and organic parsley). Directions Take 1/2 teaspoon mixed in water or juice, 2 times daily, or as directed by a health professional. Shake gently before use. Free Download - The 7 Phases of Detox Video

*This item will take a few extra days to ship* Supports Maintenance and Restoration of Muscle Health*   Clinical Applications: Supports Muscle Recovery Following Exercise* Supports Muscle Health* Supports Increased Protein Synthesis and Decreased Protein Degradation* Description:  HMB PRO features beta-hydroxy-beta-methylbutyrate (HMB), a natural metabolite of leucine that supports increased protein synthesis and decreased protein degradation. Vitamin D, which supports skeletal muscle health and function, complements HMB to render this formula an optimal choice for supporting muscle health.*