SLEEPGEVITY™ 60 Caps *

{"id":9037113983196,"title":"SLEEPGEVITY™ 60 Caps *","handle":"sleepgevity™-60-caps","description":"\u003cdiv class=\"product-single__description rte\"\u003e\n\u003cp\u003e\u003cstrong data-start=\"190\" data-end=\"233\"\u003e\u003cspan\u003eFeatured Benefits:\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli data-start=\"188\" data-end=\"277\"\u003e\n\u003cp data-start=\"190\" data-end=\"277\"\u003e\u003cstrong data-start=\"190\" data-end=\"233\"\u003ePromotes deeper, more restorative sleep\u003c\/strong\u003e by enhancing both REM and non-REM cycles*\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-start=\"278\" data-end=\"372\"\u003e\n\u003cp data-start=\"280\" data-end=\"372\"\u003e\u003cstrong data-start=\"280\" data-end=\"322\"\u003eExtends duration of deep and REM sleep\u003c\/strong\u003e to support overnight recovery and regeneration*\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-start=\"373\" data-end=\"452\"\u003e\n\u003cp data-start=\"375\" data-end=\"452\"\u003e\u003cstrong data-start=\"375\" data-end=\"409\"\u003eImproves overall sleep quality\u003c\/strong\u003e—without sedation or next-day grogginess*\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-start=\"453\" data-end=\"519\"\u003e\n\u003cp data-start=\"455\" data-end=\"519\"\u003e\u003cstrong data-start=\"455\" data-end=\"516\"\u003eSupports waking up refreshed, focused, and mentally clear\u003c\/strong\u003e*\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-start=\"520\" data-end=\"603\"\u003e\n\u003cp data-start=\"522\" data-end=\"603\"\u003e\u003cstrong data-start=\"522\" data-end=\"560\"\u003eCalms the mind and body before bed\u003c\/strong\u003e by supporting a healthy stress response*\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-start=\"604\" data-end=\"686\"\u003e\n\u003cp data-start=\"606\" data-end=\"686\"\u003e\u003cstrong data-start=\"606\" data-end=\"656\"\u003eHelps ease nervousness and mental overactivity\u003c\/strong\u003e that can delay sleep onset*\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-start=\"687\" data-end=\"772\"\u003e\n\u003cp data-start=\"689\" data-end=\"772\"\u003e\u003cstrong data-start=\"689\" data-end=\"734\"\u003eMaintains healthy evening cortisol levels\u003c\/strong\u003e for a smoother transition to sleep*\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-start=\"773\" data-end=\"868\"\u003e\n\u003cp data-start=\"775\" data-end=\"868\"\u003e\u003cstrong data-start=\"775\" data-end=\"822\"\u003eSupports balanced neurotransmitter function\u003c\/strong\u003e, including GABA, to quiet the nervous system*\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-start=\"773\" data-end=\"868\"\u003e\u003cstrong\u003eMelatonin-free \u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cb\u003e\u003cspan\u003ePEPTISLEEP™\u003c\/span\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003e\u003cstrong\u003eSLEEPgevity™ \u003c\/strong\u003eis the first formula globally to feature PeptiSleep™—a next-generation bioactive peptide developed in collaboration with Nuritas, using advanced AI-driven peptide discovery. Specifically designed to support healthy, restorative sleep, PeptiSleep™ offers a novel, non-sedating approach that works in harmony with the body’s natural circadian rhythm\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eIts mechanism of action targets two key pathways involved in sleep regulation:\u003c\/span\u003e\u003c\/p\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli class=\"MsoNormal\"\u003e\u003cspan\u003eCortisol modulation to reduce stress-related hyperarousal\u003c\/span\u003e\u003c\/li\u003e\n\u003cli class=\"MsoNormal\"\u003e\u003cspan\u003eOrexin (hypocretin) pathway downregulation, calming the central nervous system and supporting sleep onset\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eBy addressing both stress and wakefulness signaling\u003cstrong\u003e, \u003c\/strong\u003ePeptiSleep™ facilitates a smooth, anxiety-free transition into sleep, enhances sleep architecture, and helps patients stay asleep longer without disruption.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eIn clinical use, patients reported:\u003c\/span\u003e\u003c\/p\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli class=\"MsoNormal\"\u003e\u003cspan\u003eFaster sleep onset\u003c\/span\u003e\u003c\/li\u003e\n\u003cli class=\"MsoNormal\"\u003e\u003cspan\u003eImproved Deep and REM sleep\u003c\/span\u003e\u003c\/li\u003e\n\u003cli class=\"MsoNormal\"\u003e\u003cspan\u003eIncreased Heart Rate Variability (HRV)—a marker of parasympathetic nervous system activation\u003c\/span\u003e\u003c\/li\u003e\n\u003cli class=\"MsoNormal\"\u003e\u003cspan\u003eWaking up feeling clear, focused, and refreshed\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003e\u003cstrong\u003eSLEEPgevity™\u003c\/strong\u003e offers healthcare providers a non-sedating, physiologically aligned approach to sleep support—ideal for those seeking effective results without the drawbacks of traditional pharmacologic sleep aids\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cb\u003e\u003cspan\u003eTRYPTOPHAN\u003c\/span\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cb\u003e\u003cspan\u003eTryptophan\u003c\/span\u003e\u003c\/b\u003e\u003cspan\u003e was strategically included in the \u003cstrong\u003eSLEEPgevity™\u003c\/strong\u003e formula to enhance its ability to support the natural production of serotonin and melatonin, two key neurotransmitters essential for mood regulation and healthy sleep cycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eAs an essential amino acid, tryptophan serves as the precursor to 5-HTP (5-hydroxytryptophan) and subsequently serotonin, which not only influences emotional well-being but also plays a critical role in initiating and maintaining sleep. Serotonin is then converted into melatonin, the body’s primary sleep hormone that governs circadian rhythms and sleep-wake timing.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eBy supporting this pathway, tryptophan complements the cortisol-lowering and orexin-modulating effects of PeptiSleep™, helping to:\u003c\/span\u003e\u003c\/p\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli class=\"MsoNormal\"\u003e\u003cspan\u003ePromote relaxation and emotional calm\u003c\/span\u003e\u003c\/li\u003e\n\u003cli class=\"MsoNormal\"\u003e\u003cspan\u003eSupport melatonin synthesis for improved sleep onset\u003c\/span\u003e\u003c\/li\u003e\n\u003cli class=\"MsoNormal\"\u003e\u003cspan\u003eEnhance the overall depth and quality of sleep\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cb\u003e\u003cspan\u003eDHH-B (DIHYDROHONOKIOL-B) FROM MAGNOLIA BARK\u003c\/span\u003e\u003c\/b\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eMagnolia bark plays a central role in traditional Chinese medical formulas as a natural anxiolytic. Honokiol extracted from the bark has been studied independently to investigate its mechanisms of action on the central nervous system and has been shown to interact with neurotransmitter gamma-aminobutyric acid (GABA) receptors. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eA natural variant of honokiol exists with a much better profile, selectivity, and strength of the Honokiol. It is called DHH-B (or dihydrohonokiol-B) and is 20x the strength as the natural Magnolia Bark (Honokiol). DHH-B is a promising compound known for its therapeutic properties, particularly in stress relief, relaxation, and supporting healthy sleep patterns. DHH-B enhances the activity of gamma-aminobutyric acid (GABA), a key inhibitory neurotransmitter that helps reduce neuronal excitability. By increasing GABA activity, DHH-B can improve sleep quality and decrease anxiety levels.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eAdditionally, DHH-B interacts with the body's endocannabinoid system by activating cannabinoid receptors. This interaction can enhance mood, alleviate pain, and reduce inflammation, providing a comprehensive approach to emotional and physical well-being.   DHH-B has also been shown to lower adrenaline levels, helping to mitigate the physiological effects of chronic and severe stress.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eThe compound's antioxidant properties further contribute to its neuroprotective and anti-aging effects. DHH-B effectively scavenges reactive oxygen species and enhances the body's endogenous antioxidant defenses, thereby supporting neurological health and protecting against oxidative stress. It also modulates the immune response by influencing the production of pro-inflammatory cytokines.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cb\u003e\u003cspan\u003eHOLIXER™ HOLY BASIL EXTRACT \u003c\/span\u003e\u003c\/b\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eHoly Basil (Ocimum tenuiflorum), also known as Tulsi, has a long history of use in traditional Indian and Asian medical systems. Unlike common culinary basil, Holy Basil is highly revered for its medicinal properties and has been used for centuries in Ayurveda and other traditional practices. Recent research has corroborated the herb's traditional uses, highlighting its potential to support a healthy stress response, enhance sleep quality, and offer anxiolytic and adaptogenic benefits.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003e\u003cstrong\u003eSLEEPgevity™\u003c\/strong\u003e \u003c\/span\u003e\u003cspan\u003efeatures a specialized form of Holy Basil called Holixer™ which is a patented and extensively researched preparation standardized to contain at least 5% Ocimum Bioactive Complex, a unique blend of bioactive compounds including Rabdosin, Rosmarinic acid, Luteolin-7-o-beta-glucuronide, Ociglycoside I, and Apigenin-7-o-beta-glucuronide.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eThese bioactive components are thought to contribute to Holy Basil's therapeutic effects. For instance, Rosmarinic acid and Apigenin-7-o-beta-glucuronide have been shown to possess anti-inflammatory and antioxidant properties, which may help mitigate the physiological impact of stress. Luteolin-7-o-beta-glucuronide and Ociglycoside I are known for their potential neuroprotective effects, which could play a role in improving cognitive function and mood stability under stress. Rabdosin, another key component, may aid in balancing the body's stress hormones, thus supporting a more resilient stress response.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eIn clinical studies, Holixer™ Holy Basil has been observed to promote better sleep by modulating the stress response and reducing the activity of the hypothalamic-pituitary-adrenal (HPA) axis. This, in turn, helps to lower cortisol levels, which are often elevated in individuals experiencing chronic stress. Lower cortisol levels are associated with improved sleep quality and reduced feelings of anxiety.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cb\u003e\u003cspan\u003eNATURAL GABA PROBIOTIC L. PLANTARUM 815 (LP815™)\u003c\/span\u003e\u003c\/b\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eGABA is a major inhibitory neurotransmitter in the central nervous system, playing a crucial role in modulating neuronal excitability and maintaining balance in brain signaling. GABA's primary mechanism of action involves reducing the excitability of neurons, thereby aiding in mood stabilization, stress regulation, and sleep quality. Insufficient GABA levels can result in various health issues, including heightened stress, mood disturbances, poor sleep quality, and impaired cognitive function.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eGABA Probiotic  is formulated to provide a sustained release of GABA, offering continuous calming and stress support throughout the day and night. Unlike traditional GABA supplements, which often lead to a rapid but short-lived increase in GABA levels, GABA Probiotic ensures a more stable and prolonged delivery of this neurotransmitter. This is achieved through the use of a proprietary strain of Lactiplantibacillus plantarum, Lp815™, which has been specifically selected for its ability to produce GABA over an extended period.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eThe choice of Lp815™ is backed by advanced computational modeling and high-throughput screening, allowing for the identification of a strain that outperforms other industry-leading strains in sustained GABA production. The strain's unique capability lies in its robust GABA synthesis in the gastrointestinal tract, leveraging the gut-brain axis—a bidirectional communication pathway between the gut microbiota and the brain. By producing GABA locally in the gut, Lp815™ may influence central nervous system function and mood regulation, providing a dual pathway for enhancing GABA levels.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eThis sustained production is particularly beneficial compared to traditional GABA supplements, which often require multiple doses throughout the day due to their transient effects. The prolonged release profile of GABA Probiotic reduces the need for frequent redosing, thereby offering a more convenient and consistent option for patients seeking to manage stress and support mood stability.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cb\u003e\u003cspan\u003eSAFFRON EXTRACT (AS AFFRON®)\u003c\/span\u003e\u003c\/b\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eWe also included affron® Saffron Extract, which is a highly acclaimed and extensively researched form of saffron, recognized for its rapid and comprehensive effects on both brain and body health. This premium extract has been shown to work within approximately one hour, delivering significant benefits such as reduced oxidative stress, balanced neurotransmitter levels, enhanced neuroplasticity, and improvements in memory and sexual function.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eClinical evidence supports affron® as the most studied saffron extract with eight human clinical studies, demonstrating its ability to improve mood in healthy adults experiencing occasional stress,  anxiety and shown to support restful sleep through multiple mechanisms.  In a randomized, double-blind, placebo-controlled study, participants who consumed 28 mg\/day of affron® for four weeks experienced a 41% improvement in mood, along with a significant reduction in occasional stress, frustration, and tension compared to the placebo group.  It promotes relaxation and reduces pre-sleep anxiety by modulating cortisol and serotonin levels, helping calm mental overactivity that can interfere with falling asleep. Affron® has been shown to enhance overall sleep quality, reduce nighttime awakenings, and support a smoother transition into deeper sleep—without sedation or next-day grogginess.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cb\u003e\u003cspan\u003eL-THEANINE (AS L-TEAACTIVE®)\u003c\/span\u003e\u003c\/b\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eTheanine is an amino acid that is not commonly found in the human diet, as it is not one of the essential or nonessential amino acids. L-theanine is often called a “nondietary amino acid.” Because of its structure, theanine is known to reach the brain quickly following oral consumption. L-theanine is present in various food sources but is found mainly in both green and black teas. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eTheanine is found to be relaxing, but not sedating agent, and has been found to help process stress and to improve attention. It has also been found to aid in sleep quality.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eL-Theanine: A Natural Supplement for\u003c\/span\u003e\u003cspan\u003e supporting sleep through\u003cspan class=\"apple-converted-space\"\u003e\u003cb\u003e \u003c\/b\u003e\u003c\/span\u003e\u003c\/span\u003emultiple calming, non-sedating mechanisms:\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eStudies show that increasing intake of theanine can significantly \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/16930802\"\u003ereduce symptoms of anxiety\u003c\/a\u003e, such as a racing heartbeat and increased secretion of immunoglobulin A in saliva. Its effects are somewhat similar to those of a sedative, but L-theanine is far from this prescription drug. It is actually considered to be an effective \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25759004\"\u003eanxiolytic\u003c\/a\u003e, which helps to prevent the brain from producing an anxious response to stressful situations.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cb\u003e\u003cspan\u003eHow Does L-Theanine for Sleep Work?\u003c\/span\u003e\u003c\/b\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003eL-theanine is processed in the brain through the \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/15207256\"\u003eblood-brain barrier\u003c\/a\u003e. The blood-brain barrier is similar to a gateway that prevents blood borne substances from crossing over into the brain; it is a form of protection for one of the body’s most important organs. While this barrier is beneficial, it does have its downsides; most notably, it prevents many medications from reaching their target area. Research shows that 98% of small molecule neurotherapies, and 100 percent of large molecule neurotherapies \u003cspan\u003ec\u003c\/span\u003ean’t pass through the blood-brain barrier, rendering many types of common treatments for anxiety almost useless.  \u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eL-theanine is different. It uses the leucine-preferring transport system to hitch a ride across the blood-brain barrier, allowing it to target the brain directly. Essentially, theanine is better able to get to where it needs to be efficiently. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eOnce past the blood-brain barrier, L-theanine enacts a variety of neurophysiological and pharmacological effects. It has been found to up-regulate inhibitory neurotransmitters, and blocks the binding of L-glutamic acid to glutamate receptors in the brain. It has also been found to potentially modulate serotonin and dopamine in select areas of the brain. L-theanine’s inhibition of cortical neuron excitation can have anti-stress effects \u003c\/span\u003e\u003cspan\u003eimprove\u003cspan class=\"apple-converted-space\"\u003e \u003c\/span\u003e\u003c\/span\u003esleep efficiency.\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cb\u003e\u003cspan\u003eThe three main mechanisms of how L-theanine works in the brain:\u003c\/span\u003e\u003c\/b\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003e1.    \u003c\/span\u003e\u003cspan\u003eDampens the effects of excitatory brain chemicals\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan\u003e L-theanine is reported to target a number of glutamate receptors, including N-methyl-D-aspartate (NMDA), \u003c\/span\u003e\u003cspan lang=\"EL\"\u003eα\u003c\/span\u003e\u003cspan lang=\"EL\"\u003e-\u003c\/span\u003e\u003cspan\u003eamino-3-hydroxy-5-methyl- 4-isoxazolepropionic acid (AMPA) and kainite receptors, although at a much lower affinity compared to glutamate \u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003e2.    \u003c\/span\u003e\u003cspan\u003eIncreases levels of calming and mood-elevating brain chemicals\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli class=\"MsoNormal\"\u003e\n\u003cspan\u003eL-theanine also stimulates the production of the calming brain chemicals like \u003c\/span\u003e\u003cspan lang=\"EL\"\u003eγ\u003c\/span\u003e\u003cspan lang=\"EL\"\u003e-\u003c\/span\u003e\u003cspan\u003eaminobutyric acid (GABA), serotonin and dopamine adding to its calming and relaxing effects without sleepiness or impaired motor function \u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003e3.    \u003c\/span\u003e\u003cspan\u003eIncreases alpha brain waves \u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli class=\"MsoNormal\"\u003e\u003cspan\u003eThis increase in alpha wave activity is thought to contribute to L-theanine’s relaxing yet alert effects.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: rgb(255, 42, 0); font-size: 0.875rem;\"\u003e*This item may take longer to ship out*\u003c\/span\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003c\/div\u003e","published_at":"2025-08-18T17:40:26-05:00","created_at":"2025-08-18T17:37:50-05:00","vendor":"Healthgevity","type":"Supplement","tags":["Anti-inflammatory","Inflammation Support","Mental Function","Relaxation and Sleep","Sleep Suport","Supports Sleep"],"price":10999,"price_min":10999,"price_max":10999,"available":true,"price_varies":false,"compare_at_price":null,"compare_at_price_min":0,"compare_at_price_max":0,"compare_at_price_varies":false,"variants":[{"id":46835448152284,"title":"Default Title","option1":"Default Title","option2":null,"option3":null,"sku":null,"requires_shipping":true,"taxable":true,"featured_image":null,"available":true,"name":"SLEEPGEVITY™ 60 Caps *","public_title":null,"options":["Default Title"],"price":10999,"weight":170,"compare_at_price":null,"inventory_management":"shopify","barcode":null,"requires_selling_plan":false,"selling_plan_allocations":[],"quantity_rule":{"min":1,"max":null,"increment":1}}],"images":["\/\/shop.connersclinic.com\/cdn\/shop\/files\/sleepgevity-60-caps-healthgevity-conners-clinic-1186045507.png?v=1755564548","\/\/shop.connersclinic.com\/cdn\/shop\/files\/sleepgevity-60-caps-healthgevity-conners-clinic-1186045506.png?v=1755564544","\/\/shop.connersclinic.com\/cdn\/shop\/files\/sleepgevity-60-caps-healthgevity-conners-clinic-1186045505.png?v=1755564541"],"featured_image":"\/\/shop.connersclinic.com\/cdn\/shop\/files\/sleepgevity-60-caps-healthgevity-conners-clinic-1186045507.png?v=1755564548","options":["Title"],"media":[{"alt":"SLEEPGEVITY™ 60 Caps * Healthgevity Supplement - Conners Clinic","id":35421539074268,"position":1,"preview_image":{"aspect_ratio":0.512,"height":1336,"width":684,"src":"\/\/shop.connersclinic.com\/cdn\/shop\/files\/sleepgevity-60-caps-healthgevity-conners-clinic-1186045507.png?v=1755564548"},"aspect_ratio":0.512,"height":1336,"media_type":"image","src":"\/\/shop.connersclinic.com\/cdn\/shop\/files\/sleepgevity-60-caps-healthgevity-conners-clinic-1186045507.png?v=1755564548","width":684},{"alt":"SLEEPGEVITY™ 60 Caps * Healthgevity Supplement - Conners Clinic","id":35421539238108,"position":2,"preview_image":{"aspect_ratio":0.898,"height":1234,"width":1108,"src":"\/\/shop.connersclinic.com\/cdn\/shop\/files\/sleepgevity-60-caps-healthgevity-conners-clinic-1186045506.png?v=1755564544"},"aspect_ratio":0.898,"height":1234,"media_type":"image","src":"\/\/shop.connersclinic.com\/cdn\/shop\/files\/sleepgevity-60-caps-healthgevity-conners-clinic-1186045506.png?v=1755564544","width":1108},{"alt":"SLEEPGEVITY™ 60 Caps * Healthgevity Supplement - Conners Clinic","id":35421539565788,"position":3,"preview_image":{"aspect_ratio":1.129,"height":1160,"width":1310,"src":"\/\/shop.connersclinic.com\/cdn\/shop\/files\/sleepgevity-60-caps-healthgevity-conners-clinic-1186045505.png?v=1755564541"},"aspect_ratio":1.129,"height":1160,"media_type":"image","src":"\/\/shop.connersclinic.com\/cdn\/shop\/files\/sleepgevity-60-caps-healthgevity-conners-clinic-1186045505.png?v=1755564541","width":1310}],"requires_selling_plan":false,"selling_plan_groups":[],"content":"\u003cdiv class=\"product-single__description rte\"\u003e\n\u003cp\u003e\u003cstrong data-start=\"190\" data-end=\"233\"\u003e\u003cspan\u003eFeatured Benefits:\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli data-start=\"188\" data-end=\"277\"\u003e\n\u003cp data-start=\"190\" data-end=\"277\"\u003e\u003cstrong data-start=\"190\" data-end=\"233\"\u003ePromotes deeper, more restorative sleep\u003c\/strong\u003e by enhancing both REM and non-REM cycles*\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-start=\"278\" data-end=\"372\"\u003e\n\u003cp data-start=\"280\" data-end=\"372\"\u003e\u003cstrong data-start=\"280\" data-end=\"322\"\u003eExtends duration of deep and REM sleep\u003c\/strong\u003e to support overnight recovery and regeneration*\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-start=\"373\" data-end=\"452\"\u003e\n\u003cp data-start=\"375\" data-end=\"452\"\u003e\u003cstrong data-start=\"375\" data-end=\"409\"\u003eImproves overall sleep quality\u003c\/strong\u003e—without sedation or next-day grogginess*\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-start=\"453\" data-end=\"519\"\u003e\n\u003cp data-start=\"455\" data-end=\"519\"\u003e\u003cstrong data-start=\"455\" data-end=\"516\"\u003eSupports waking up refreshed, focused, and mentally clear\u003c\/strong\u003e*\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-start=\"520\" data-end=\"603\"\u003e\n\u003cp data-start=\"522\" data-end=\"603\"\u003e\u003cstrong data-start=\"522\" data-end=\"560\"\u003eCalms the mind and body before bed\u003c\/strong\u003e by supporting a healthy stress response*\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-start=\"604\" data-end=\"686\"\u003e\n\u003cp data-start=\"606\" data-end=\"686\"\u003e\u003cstrong data-start=\"606\" data-end=\"656\"\u003eHelps ease nervousness and mental overactivity\u003c\/strong\u003e that can delay sleep onset*\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-start=\"687\" data-end=\"772\"\u003e\n\u003cp data-start=\"689\" data-end=\"772\"\u003e\u003cstrong data-start=\"689\" data-end=\"734\"\u003eMaintains healthy evening cortisol levels\u003c\/strong\u003e for a smoother transition to sleep*\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-start=\"773\" data-end=\"868\"\u003e\n\u003cp data-start=\"775\" data-end=\"868\"\u003e\u003cstrong data-start=\"775\" data-end=\"822\"\u003eSupports balanced neurotransmitter function\u003c\/strong\u003e, including GABA, to quiet the nervous system*\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-start=\"773\" data-end=\"868\"\u003e\u003cstrong\u003eMelatonin-free \u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cb\u003e\u003cspan\u003ePEPTISLEEP™\u003c\/span\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003e\u003cstrong\u003eSLEEPgevity™ \u003c\/strong\u003eis the first formula globally to feature PeptiSleep™—a next-generation bioactive peptide developed in collaboration with Nuritas, using advanced AI-driven peptide discovery. Specifically designed to support healthy, restorative sleep, PeptiSleep™ offers a novel, non-sedating approach that works in harmony with the body’s natural circadian rhythm\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eIts mechanism of action targets two key pathways involved in sleep regulation:\u003c\/span\u003e\u003c\/p\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli class=\"MsoNormal\"\u003e\u003cspan\u003eCortisol modulation to reduce stress-related hyperarousal\u003c\/span\u003e\u003c\/li\u003e\n\u003cli class=\"MsoNormal\"\u003e\u003cspan\u003eOrexin (hypocretin) pathway downregulation, calming the central nervous system and supporting sleep onset\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eBy addressing both stress and wakefulness signaling\u003cstrong\u003e, \u003c\/strong\u003ePeptiSleep™ facilitates a smooth, anxiety-free transition into sleep, enhances sleep architecture, and helps patients stay asleep longer without disruption.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eIn clinical use, patients reported:\u003c\/span\u003e\u003c\/p\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli class=\"MsoNormal\"\u003e\u003cspan\u003eFaster sleep onset\u003c\/span\u003e\u003c\/li\u003e\n\u003cli class=\"MsoNormal\"\u003e\u003cspan\u003eImproved Deep and REM sleep\u003c\/span\u003e\u003c\/li\u003e\n\u003cli class=\"MsoNormal\"\u003e\u003cspan\u003eIncreased Heart Rate Variability (HRV)—a marker of parasympathetic nervous system activation\u003c\/span\u003e\u003c\/li\u003e\n\u003cli class=\"MsoNormal\"\u003e\u003cspan\u003eWaking up feeling clear, focused, and refreshed\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003e\u003cstrong\u003eSLEEPgevity™\u003c\/strong\u003e offers healthcare providers a non-sedating, physiologically aligned approach to sleep support—ideal for those seeking effective results without the drawbacks of traditional pharmacologic sleep aids\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cb\u003e\u003cspan\u003eTRYPTOPHAN\u003c\/span\u003e\u003c\/b\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cb\u003e\u003cspan\u003eTryptophan\u003c\/span\u003e\u003c\/b\u003e\u003cspan\u003e was strategically included in the \u003cstrong\u003eSLEEPgevity™\u003c\/strong\u003e formula to enhance its ability to support the natural production of serotonin and melatonin, two key neurotransmitters essential for mood regulation and healthy sleep cycles.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eAs an essential amino acid, tryptophan serves as the precursor to 5-HTP (5-hydroxytryptophan) and subsequently serotonin, which not only influences emotional well-being but also plays a critical role in initiating and maintaining sleep. Serotonin is then converted into melatonin, the body’s primary sleep hormone that governs circadian rhythms and sleep-wake timing.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eBy supporting this pathway, tryptophan complements the cortisol-lowering and orexin-modulating effects of PeptiSleep™, helping to:\u003c\/span\u003e\u003c\/p\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli class=\"MsoNormal\"\u003e\u003cspan\u003ePromote relaxation and emotional calm\u003c\/span\u003e\u003c\/li\u003e\n\u003cli class=\"MsoNormal\"\u003e\u003cspan\u003eSupport melatonin synthesis for improved sleep onset\u003c\/span\u003e\u003c\/li\u003e\n\u003cli class=\"MsoNormal\"\u003e\u003cspan\u003eEnhance the overall depth and quality of sleep\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cb\u003e\u003cspan\u003eDHH-B (DIHYDROHONOKIOL-B) FROM MAGNOLIA BARK\u003c\/span\u003e\u003c\/b\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eMagnolia bark plays a central role in traditional Chinese medical formulas as a natural anxiolytic. Honokiol extracted from the bark has been studied independently to investigate its mechanisms of action on the central nervous system and has been shown to interact with neurotransmitter gamma-aminobutyric acid (GABA) receptors. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eA natural variant of honokiol exists with a much better profile, selectivity, and strength of the Honokiol. It is called DHH-B (or dihydrohonokiol-B) and is 20x the strength as the natural Magnolia Bark (Honokiol). DHH-B is a promising compound known for its therapeutic properties, particularly in stress relief, relaxation, and supporting healthy sleep patterns. DHH-B enhances the activity of gamma-aminobutyric acid (GABA), a key inhibitory neurotransmitter that helps reduce neuronal excitability. By increasing GABA activity, DHH-B can improve sleep quality and decrease anxiety levels.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eAdditionally, DHH-B interacts with the body's endocannabinoid system by activating cannabinoid receptors. This interaction can enhance mood, alleviate pain, and reduce inflammation, providing a comprehensive approach to emotional and physical well-being.   DHH-B has also been shown to lower adrenaline levels, helping to mitigate the physiological effects of chronic and severe stress.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eThe compound's antioxidant properties further contribute to its neuroprotective and anti-aging effects. DHH-B effectively scavenges reactive oxygen species and enhances the body's endogenous antioxidant defenses, thereby supporting neurological health and protecting against oxidative stress. It also modulates the immune response by influencing the production of pro-inflammatory cytokines.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cb\u003e\u003cspan\u003eHOLIXER™ HOLY BASIL EXTRACT \u003c\/span\u003e\u003c\/b\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eHoly Basil (Ocimum tenuiflorum), also known as Tulsi, has a long history of use in traditional Indian and Asian medical systems. Unlike common culinary basil, Holy Basil is highly revered for its medicinal properties and has been used for centuries in Ayurveda and other traditional practices. Recent research has corroborated the herb's traditional uses, highlighting its potential to support a healthy stress response, enhance sleep quality, and offer anxiolytic and adaptogenic benefits.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003e\u003cstrong\u003eSLEEPgevity™\u003c\/strong\u003e \u003c\/span\u003e\u003cspan\u003efeatures a specialized form of Holy Basil called Holixer™ which is a patented and extensively researched preparation standardized to contain at least 5% Ocimum Bioactive Complex, a unique blend of bioactive compounds including Rabdosin, Rosmarinic acid, Luteolin-7-o-beta-glucuronide, Ociglycoside I, and Apigenin-7-o-beta-glucuronide.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eThese bioactive components are thought to contribute to Holy Basil's therapeutic effects. For instance, Rosmarinic acid and Apigenin-7-o-beta-glucuronide have been shown to possess anti-inflammatory and antioxidant properties, which may help mitigate the physiological impact of stress. Luteolin-7-o-beta-glucuronide and Ociglycoside I are known for their potential neuroprotective effects, which could play a role in improving cognitive function and mood stability under stress. Rabdosin, another key component, may aid in balancing the body's stress hormones, thus supporting a more resilient stress response.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eIn clinical studies, Holixer™ Holy Basil has been observed to promote better sleep by modulating the stress response and reducing the activity of the hypothalamic-pituitary-adrenal (HPA) axis. This, in turn, helps to lower cortisol levels, which are often elevated in individuals experiencing chronic stress. Lower cortisol levels are associated with improved sleep quality and reduced feelings of anxiety.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cb\u003e\u003cspan\u003eNATURAL GABA PROBIOTIC L. PLANTARUM 815 (LP815™)\u003c\/span\u003e\u003c\/b\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eGABA is a major inhibitory neurotransmitter in the central nervous system, playing a crucial role in modulating neuronal excitability and maintaining balance in brain signaling. GABA's primary mechanism of action involves reducing the excitability of neurons, thereby aiding in mood stabilization, stress regulation, and sleep quality. Insufficient GABA levels can result in various health issues, including heightened stress, mood disturbances, poor sleep quality, and impaired cognitive function.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eGABA Probiotic  is formulated to provide a sustained release of GABA, offering continuous calming and stress support throughout the day and night. Unlike traditional GABA supplements, which often lead to a rapid but short-lived increase in GABA levels, GABA Probiotic ensures a more stable and prolonged delivery of this neurotransmitter. This is achieved through the use of a proprietary strain of Lactiplantibacillus plantarum, Lp815™, which has been specifically selected for its ability to produce GABA over an extended period.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eThe choice of Lp815™ is backed by advanced computational modeling and high-throughput screening, allowing for the identification of a strain that outperforms other industry-leading strains in sustained GABA production. The strain's unique capability lies in its robust GABA synthesis in the gastrointestinal tract, leveraging the gut-brain axis—a bidirectional communication pathway between the gut microbiota and the brain. By producing GABA locally in the gut, Lp815™ may influence central nervous system function and mood regulation, providing a dual pathway for enhancing GABA levels.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eThis sustained production is particularly beneficial compared to traditional GABA supplements, which often require multiple doses throughout the day due to their transient effects. The prolonged release profile of GABA Probiotic reduces the need for frequent redosing, thereby offering a more convenient and consistent option for patients seeking to manage stress and support mood stability.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cb\u003e\u003cspan\u003eSAFFRON EXTRACT (AS AFFRON®)\u003c\/span\u003e\u003c\/b\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eWe also included affron® Saffron Extract, which is a highly acclaimed and extensively researched form of saffron, recognized for its rapid and comprehensive effects on both brain and body health. This premium extract has been shown to work within approximately one hour, delivering significant benefits such as reduced oxidative stress, balanced neurotransmitter levels, enhanced neuroplasticity, and improvements in memory and sexual function.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eClinical evidence supports affron® as the most studied saffron extract with eight human clinical studies, demonstrating its ability to improve mood in healthy adults experiencing occasional stress,  anxiety and shown to support restful sleep through multiple mechanisms.  In a randomized, double-blind, placebo-controlled study, participants who consumed 28 mg\/day of affron® for four weeks experienced a 41% improvement in mood, along with a significant reduction in occasional stress, frustration, and tension compared to the placebo group.  It promotes relaxation and reduces pre-sleep anxiety by modulating cortisol and serotonin levels, helping calm mental overactivity that can interfere with falling asleep. Affron® has been shown to enhance overall sleep quality, reduce nighttime awakenings, and support a smoother transition into deeper sleep—without sedation or next-day grogginess.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cb\u003e\u003cspan\u003eL-THEANINE (AS L-TEAACTIVE®)\u003c\/span\u003e\u003c\/b\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eTheanine is an amino acid that is not commonly found in the human diet, as it is not one of the essential or nonessential amino acids. L-theanine is often called a “nondietary amino acid.” Because of its structure, theanine is known to reach the brain quickly following oral consumption. L-theanine is present in various food sources but is found mainly in both green and black teas. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eTheanine is found to be relaxing, but not sedating agent, and has been found to help process stress and to improve attention. It has also been found to aid in sleep quality.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eL-Theanine: A Natural Supplement for\u003c\/span\u003e\u003cspan\u003e supporting sleep through\u003cspan class=\"apple-converted-space\"\u003e\u003cb\u003e \u003c\/b\u003e\u003c\/span\u003e\u003c\/span\u003emultiple calming, non-sedating mechanisms:\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eStudies show that increasing intake of theanine can significantly \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/16930802\"\u003ereduce symptoms of anxiety\u003c\/a\u003e, such as a racing heartbeat and increased secretion of immunoglobulin A in saliva. Its effects are somewhat similar to those of a sedative, but L-theanine is far from this prescription drug. It is actually considered to be an effective \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25759004\"\u003eanxiolytic\u003c\/a\u003e, which helps to prevent the brain from producing an anxious response to stressful situations.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cb\u003e\u003cspan\u003eHow Does L-Theanine for Sleep Work?\u003c\/span\u003e\u003c\/b\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003eL-theanine is processed in the brain through the \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/15207256\"\u003eblood-brain barrier\u003c\/a\u003e. The blood-brain barrier is similar to a gateway that prevents blood borne substances from crossing over into the brain; it is a form of protection for one of the body’s most important organs. While this barrier is beneficial, it does have its downsides; most notably, it prevents many medications from reaching their target area. Research shows that 98% of small molecule neurotherapies, and 100 percent of large molecule neurotherapies \u003cspan\u003ec\u003c\/span\u003ean’t pass through the blood-brain barrier, rendering many types of common treatments for anxiety almost useless.  \u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eL-theanine is different. It uses the leucine-preferring transport system to hitch a ride across the blood-brain barrier, allowing it to target the brain directly. Essentially, theanine is better able to get to where it needs to be efficiently. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003eOnce past the blood-brain barrier, L-theanine enacts a variety of neurophysiological and pharmacological effects. It has been found to up-regulate inhibitory neurotransmitters, and blocks the binding of L-glutamic acid to glutamate receptors in the brain. It has also been found to potentially modulate serotonin and dopamine in select areas of the brain. L-theanine’s inhibition of cortical neuron excitation can have anti-stress effects \u003c\/span\u003e\u003cspan\u003eimprove\u003cspan class=\"apple-converted-space\"\u003e \u003c\/span\u003e\u003c\/span\u003esleep efficiency.\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cb\u003e\u003cspan\u003eThe three main mechanisms of how L-theanine works in the brain:\u003c\/span\u003e\u003c\/b\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003e1.    \u003c\/span\u003e\u003cspan\u003eDampens the effects of excitatory brain chemicals\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan\u003e L-theanine is reported to target a number of glutamate receptors, including N-methyl-D-aspartate (NMDA), \u003c\/span\u003e\u003cspan lang=\"EL\"\u003eα\u003c\/span\u003e\u003cspan lang=\"EL\"\u003e-\u003c\/span\u003e\u003cspan\u003eamino-3-hydroxy-5-methyl- 4-isoxazolepropionic acid (AMPA) and kainite receptors, although at a much lower affinity compared to glutamate \u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003e2.    \u003c\/span\u003e\u003cspan\u003eIncreases levels of calming and mood-elevating brain chemicals\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli class=\"MsoNormal\"\u003e\n\u003cspan\u003eL-theanine also stimulates the production of the calming brain chemicals like \u003c\/span\u003e\u003cspan lang=\"EL\"\u003eγ\u003c\/span\u003e\u003cspan lang=\"EL\"\u003e-\u003c\/span\u003e\u003cspan\u003eaminobutyric acid (GABA), serotonin and dopamine adding to its calming and relaxing effects without sleepiness or impaired motor function \u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003e3.    \u003c\/span\u003e\u003cspan\u003eIncreases alpha brain waves \u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli class=\"MsoNormal\"\u003e\u003cspan\u003eThis increase in alpha wave activity is thought to contribute to L-theanine’s relaxing yet alert effects.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: rgb(255, 42, 0); font-size: 0.875rem;\"\u003e*This item may take longer to ship out*\u003c\/span\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003c\/div\u003e"}