Ortho-Molecular

CLINICAL APPLICATIONS Supports a State of Calmness and Relaxation Promotes Balanced Mood Enhances Cognitive Performance and Memory INGREDIENT BENEFITS L-Theanine L-theanine is an amino acid found abundantly in green tea. L-theanine has been shown to quickly improve stress perception and resilience. GABA Gamma-amino butyric acid (GABA) is the primary inhibitory neurotransmitter in the brain. GABA provides a calming effect and is a major component of the body’s stress-fighting mechanisms. GABA has been shown in published research studies to promote a state of relaxation. Huperzine Alkaloids Huperzia serrata (whole plant extract), or Chinese club moss is a nootropic known for its potent and selective acetylcholinesterase inhibition.  Huperzine A helps to improve memory and support optimal cognitive health. OVERVIEW Neurotransmitters are the chemical messengers that regulate mood, memory, sleep cycle and daily stress. Nootropics are substances that promote improved cognitive function, particularly executive functions, memory, creativity, or motivation, in healthy individuals. CopaCalm contains a combination of ingredients designed to address stressful situations in the moment or may be taken in preparation for these events.  CopaCalm includes support for focus, mood balance and calming relaxation without drowsiness.  Suggested Use: 2 full droppers (about 2 mL) two to three times per day or as recommended by your health care professional.

Core Restore is a comprehensive 7- or 14-day diet, lifestyle and nutrient program designed to reduce toxic burden and support Phase I and II liver detoxification function. CLINICAL APPLICATIONS Revitalizes Liver Health and Supports Natural Detoxification Mechanisms Focuses on Both Phases of Liver Detoxification Provides Micronutrients, Phytonutrients, and Cofactors that Support Detoxification of Xenobiotics and Xenoestrogens Supports Healthy Estrogen Metabolism Increases Antioxidant Protection and Glutathione Production Promotes Gastrointestinal Health OVERVIEW Core Restore is a strategic system designed to safely enhance and promote the primary pathways of detoxification in the liver. The Core Restore kit provides three active formulas – Core Support, Alpha Base, and PhytoCore – which function synergistically to support Phase I and Phase II pathways of liver detoxification to help neutralize environmental pollutants, hormone disruptors, unhealthy estrogen metabolites, xenoestrogens (synthetic compounds that imitate estrogen), and other harmful toxins. This powerful trio of specialized formulas provides essential micronutrients, phytonutrients, and a source of easily digested, low-allergen protein that purifies the liver and fuel optimal biotransformation. The Core Restore kit is an easy-to-follow, 7- or 14-day program, complete with an in-depth Patient Handbook, designed to reduce the incoming burden of toxins and help restore optimal health. Suggested Use Mix 2 scoops of Core Support with 8 oz. of water or the beverage of your choice two times daily or as recommended by your health care professional. INGREDIENT BENEFITS Core Support powder is a primary component of the Core Restore program, and provides key nutrients needed to support Phase II liver detoxification. Core Support Core Support powder enhances Phase II detoxification by providing clean protein, gentle fiber, and specific nutrients which help eliminate toxins during the seven-day detoxification program. Core Support provides nutrients needed for Phase II detox including N-acetyl cysteine, glycine, taurine, lipoic acid, green tea extract, ellagic acid, and a unique blend of vegetable phytonutrients. The antioxidant activity of this unique blend of nutrients is protective against cell damage by free radicals and helps induce Phase II enzymes which facilitate the removal of toxins from the body and scavenge free radicals. Research has shown that glutathione and the amino acid cysteine help to regulate Phase II conjugation reactions and epigallocatechin-3-gallate (EGCG), the major polyphenol in green tea, has also been shown to induce expression of glutathione S-transferase and glutathione peroxidase. Core Support provides organic brown rice protein as a satisfying and hypoallergenic energy source, as well as 6-7 g of fiber per serving, essential for binding toxins for elimination.

Core Restore is a comprehensive 7- or 14-day diet, lifestyle and nutrient program designed to reduce toxic burden and support Phase I and II liver detoxification function. CLINICAL APPLICATIONS Revitalizes Liver Health and Supports Natural Detoxification Mechanisms Focuses on Both Phases of Liver Detoxification Provides Micronutrients, Phytonutrients, and Cofactors that Support Detoxification of Xenobiotics and Xenoestrogens Supports Healthy Estrogen Metabolism Increases Antioxidant Protection and Glutathione Production Promotes Gastrointestinal Health OVERVIEW The Core Restore Kit is a strategic system designed to safely enhance and promote the primary pathways of detoxification in the liver. The Core Restore kit provides three active formulas – Core Support, Alpha Base, and PhytoCore – which function synergistically to support Phase I and Phase II pathways of liver detoxification to help neutralize environmental pollutants, hormone disruptors, unhealthy estrogen metabolites, xenoestrogens (synthetic compounds that imitate estrogen), and other harmful toxins. This powerful trio of specialized formulas provides essential micronutrients, phytonutrients, and a source of easily digested, low-allergen protein that purifies the liver and fuel optimal biotransformation. The Core Restore Kit is an easy-to-follow, 7- or 14-day program, complete with an in-depth Patient Handbook, designed to reduce the incoming burden of toxins and help restore optimal health. Suggested Use Mix 2 scoops of Core Support with 8 oz. of water or the beverage of your choice two times daily or as recommended by your health care professional. INGREDIENT BENEFITS Core Support powder is a primary component of the Core Restore program, and provides key nutrients needed to support Phase II liver detoxification. Core Support Core Support powder enhances Phase II detoxification by providing clean protein, gentle fiber, and specific nutrients which help eliminate toxins during the seven-day detoxification program. Core Support provides nutrients needed for Phase II detox including N-acetyl cysteine, glycine, taurine, lipoic acid, green tea extract, ellagic acid, and a unique blend of vegetable phytonutrients. The antioxidant activity of this unique blend of nutrients is protective against cell damage by free radicals and helps induce Phase II enzymes which facilitate the removal of toxins from the body and scavenge free radicals. Research has shown that glutathione and the amino acid cysteine help to regulate Phase II conjugation reactions and epigallocatechin-3-gallate (EGCG), the major polyphenol in green tea, has also been shown to induce expression of glutathione S-transferase and glutathione peroxidase. Core Support provides organic brown rice protein as a satisfying and hypoallergenic energy source, as well as 6-7 g of fiber per serving, essential for binding toxins for elimination.

This may be fulfilled by a product this manufacturer Private Labels for us Note: We Private Label this product from Orthomolecular so you may receive it in our private label - Clear Hist Jr. It is the EXACT same product!!! CLINICAL APPLICATIONS Supports Immune Balance in Hypersensitive Individuals Supports Sinus and Respiratory Health Promotes Normal Viscosity of Mucus Clears Nasal Passages OVERVIEW D-Hist Jr. / Clear Hist Jr. is a great-tasting, chewable tablet that includes a targeted blend of flavonoids, antioxidants, proteolytic enzymes and botanicals designed to provide comprehensive support for children with seasonal challenges caused by common environmental allergens. D-Hist Jr. /Clear Hist Jr. includes quercetin, a powerful flavonoid to support healthy histamine levels. It supplies bromelain to enhance the absorption of quercetin and to support mucosal tissue health and stinging nettles leaf to balance hyper-immune response. N-acetyl cysteine clears the airways by promoting normal viscosity of mucus. This unique nutritional combination safely promotes healthy nasal and sinus passages for children with elevated histamine and respiratory irritation. Suggested Use: 1 tablet as needed or as recommended by your health care professional INGREDIENT BENEFITS Quercetin Quercetin is a biologically active flavonoid antioxidant that is widely distributed in plants, oak trees, onions and tea leaves. Quercetin has strong antioxidant activity and has also been shown to support immune health by mediating the release of inflammatory compounds, including leukotrienes and prostaglandins. Quercetin is known for its ability to stabilize mast cells, which diminishes the release of histamine, the compound known to cause hypersensitivity reactions during seasonal changes. Stinging Nettles Leaf Urtica dioica, commonly known as stinging nettles, is a plant that has been shown to balance immune response, specifically in the airways and nasal passages. Studies have shown that the extract of stinging nettles leaf balances several of inflammatory activities that affect respiratory health. In addition to controlling mast-cell degranulation, stinging nettles leaf controls prostaglandin formation and histamine action, thus contributing to a balanced inflammatory response. Bromelain Bromelain is a plant enzyme naturally found on the stem and fruit of the pineapple plant. Bromelain is a proteolytic enzyme that aids in in the breakdown of large protein complexes, including antigenic compounds. Bromelain has been shown to enhance the absorption of quercetin and to reduce circulating allergenic protein complexes associated with hyper-immune sensitivity and seasonal discomfort. N-Acetyl Cysteine N-acetyl cysteine (NAC) is an amino acid precursor to one of the most important antioxidants in the body: glutathione. Both glutathione and NAC help reduce the viscosity of the mucus allowing for clearing of the airways and improved respiratory health. Vitamin C Because vitamin C cannot be synthesized by the human body, it is an essential nutrient that must be consumed in the diet. Among its numerous health-promoting properties, vitamin C supports the immune system and is also a potent antioxidant. When the body is under a significant amount of stress, vitamin C is excreted rapidly. Vitamin C has many immune boosting properties, but is distinctively beneficial for individuals with seasonal discomfort because of its ability to deactivate histamine.

DG Protect is a uniquely designed digestive enzyme targeted to help maintain healthy gluten and dairy digestion. DG Protect includes both endopeptidase and exopeptidase activity chosen for their ability to hydrolyze gluten proteins, as well as a unique mixture of protease enzymes and lactase to assist the digestion of multiple constituents of dairy products.  

DGL, or deglycyrrhizinated licorice, is a form of licorice root that has been specially processed to contain only biologically active flavonoids, without glycyrrhizin. The deglycyrrhized form of licorice allows for higher dosing of supportive flavonoids, which helps maintain a healthy mucosal surface in the stomach. Traditionally used to support GI-related complaints, research has shown DGL promotes bacterial balance and a healthy esophageal lining. Along with DGL, the formula also contains aloe vera, slippery elm bark and marshmallow root, all used to soothe the GI tract. Each serving contains 150mg DGL. Overview Approximately 25 million Americans will suffer from GI mucosal complaints at some point in their lifetimes. While such discomfort was originally thought to arise from stress, spicy foods, alcohol consumption, gastric acid production or heredity, today it is known that common bacteria from food is often the root cause. Since almost 80% of pathogens enter the body either through mucosal tissue or stay localized on mucosal surfaces, a healthy mucosal lining is of the utmost importance for digestive health. DGL supports gastrointestinal health by accelerating the secretion rate of mucus by the gastric and esophageal mucosa, helping to protect tissues. This unique licorice extract contains only biologically active flavonoids, without glycyrrhizin, for targeted usage in the GI tract. DGL The formula includes GutGard®, a clinically studied form of deglycyrrhized licorice that provides improved control of the glycyrrhized content and a rich source of flavonoids. In a clinical trial, 56% of subjects receiving GutGard® showed marked improvement compared to placebo.2 In another study of 874 patients comparing the effects of DGL and cimetidine (another known therapy), it was found that DGL was effective in relieving minor GI discomfort. Marshmallow Root Marshmallow root is a traditional soothing herb with a long history of use for coating the gastric lining. Marshmallow root contains mucilage polysaccharides, which swell when mixed with liquid, providing a soothing property to mucous membranes.5 The German Commission E has approved the use of marshmallow root for promoting a normal inflammatory process within the gastric mucosa. The nonofficial British Herbal Compendium 1st edition also indicates marshmallow root for soothing the stomach and intestinal tract. Aloe Vera Concentrate Aloe vera, like marshmallow root and slippery elm bark, is a soothing herb that has been used throughout history, and has been shown to maintain normal inflammatory balance. Specifically, studies have shown aloe vera is beneficial to the gastric mucosa due in part by its ability to balance stomach acid levels and promote healthy mucus production.6-8 An animal study examining the effects of aloe vera on gastric acid secretion and gastric mucosal health found aloe vera balanced gastric acid secretion and was found to balance minor changes in gastric acid secretion and at low doses protected mucosa from temporary influxes of excess gastric acid. Slippery Elm Bark Slippery elm bark is a traditional soothing herb that has been used for centuries. Slippery elm bark is rich in mucilage, which helps maintain normal inflammatory balance. Directions 2 capsules per day or as recommended by your health care professional. Does Not Contain Gluten, yeast, artificial colors and flavors.

CLINICAL APPLICATIONS Provides Key Nutrients for Blood Sugar Regulation Helps Maintain Healthy Blood Sugar Levels Supports Normal Cellular Metabolism OVERVIEW Maintaining healthy blood sugar (glucose) levels can often pose a challenge because, on average, Americans spend 21 hours a day being sedentary. Additionally, we consume foods that are highly processed, refined, and contain excessive levels of sugar while offering very little in the way of micronutrients and fiber. Combining these lifestyle practices with genetic predisposition and high stress patterns make it very difficult to maintain adequate blood sugar levels. Healthy blood sugar regulation is a complex process that requires a number of metabolic factors working at optimal capacity. Part of this process includes a region in the pancreas called the Islets of Langerhans. This region has various types of cells involved in regulating blood sugar levels. If blood glucose levels fall (which often occurs due to stress or lack of food intake for an extended period of time), the alpha cells of this region secrete glucagon, a hormone that triggers the release of stored glucose (glycogen) from the liver and skeletal muscles. Conversely, when blood sugar levels are elevated, beta cells in the Islets of Langerhans secrete the hormone insulin. Insulin causes liver cells, muscle cells and fat cells to take up glucose from the bloodstream. The delicate balance of blood sugar levels is crucial for regulating the body’s production of energy. Micronutrients such as chromium and biotin are required to support enzymatic reactions and cellular signaling systems that maintain the body’s homeostasis. Diaxinol® is a natural and synergistic formula for maintaining balanced blood sugar. Through enhanced signaling at the cellular level, Diaxinol®’s blend of natural extracts and vitamins support healthy blood glucose levels. Diaxinol®’s unique and effective formulation contains five ingredients provided at targeted doses for maximum efficacy. Alpha lipoic acid (ALA) is a potent antioxidant that supports insulin regulation, glucose utilization, and cellular metabolism. Cinnulin®, a patented 20:1 aqueous cinnamon extract, supports both balanced glucose metabolism and healthy blood lipid levels. Chromium is added to support glucose tolerance factor (GTF) production, a critical component in cellular uptake of glucose. Suggested Use: 2 capsules per day or as recommended by your health care professional INGREDIENT BENEFITS Alpha Lipoic Acid Alpha lipoic acid (ALA) is a nutrient required for cellular metabolism, specifically the breakdown of carbohydrates and fatty acids. ALA has been shown to support healthy blood sugar balance by activating an enzyme called adenosine mono-phosphate kinase (AMPK), a major regulator of cellular energy. AMPK coordinates both long-term and short-term metabolic changes, leading to an improvement in energy production and a reduction of energy storage. AMPK activates cellular metabolism by improving insulin sensitivity, downregulating genes involved in fat storage and activating genes involved with burning fat. A study using a dose of 600 mg/day of ALA over three months demonstrated that ALA helps support healthy lipid levels while improving oxidative stress (reducing free radical damage) by 38%. An additional study examining the effects of ALA on 74 subjects found that within the four-week, placebo-controlled trial, administration of 600 mg of ALA per day significantly enhanced glucose transport and utilization. ALA is also a potent antioxidant. It scavenges free radicals while aiding in the regeneration of the body’s antioxidants including vitamin C, vitamin E and glutathione. Through its antioxidant-boosting mechanisms, ALA helps maintain healthy blood vessel and circulatory health. Cinnulin® (Cinnamon Bark Extract) Numerous studies have demonstrated that cinnamon has a beneficial effect on maintaining healthy blood sugar levels. Cinnamon acts by inhibiting several enzymes that play a role in insulin resistance leading to an increase in insulin sensitivity. Chromium Chromium is a critical piece in the molecule glucose tolerance factor (GTF), a complex shown to be crucial for the uptake of glucose into the cells. Studies using 1,000 mcg/day of chromium have demonstrated that chromium helps maintain healthy blood sugar balance, insulin sensitivity and blood lipids. Biotin Biotin is a B vitamin that plays a major role in energy production by acting as a coenzyme for several carboxylase enzymes involved in the metabolism of fatty acids and amino acids. Biotin also plays numerous roles in maintaining healthy blood sugar balance such as, stimulating glucose-induced insulin secretion, enhancing insulin sensitivity and accelerating glucose metabolism in the liver and pancreas. Biotin also activates glucokinase, a critical enzyme involved in glucose utilization.

CLINICAL APPLICATIONS Supports Cardiovascular and Neurologic Health Supports Homocysteine Balance Supports Healthy Arterial Function Maintains Normal Inflammatory Balance OVERVIEW For some women, the accompanying signs and effects that can occur during the transition years can be strong enough to significantly disrupt daily activities and sense of well-being. Femarin contains five key ingredients that provide proven phytoestrogen shown to support a woman’s unique needs during this period. Specifically, Femarin’s formula addresses hormonal balance, maintains normal inflammatory balance and provides antioxidant support, as well as cardiovascular and bone support for a full spectrum of protection and menopausal symptom relief. Suggested Use: 2 capsules per day in divided doses or as recommended by your health care professional. INGREDIENT BENEFITS Black Cohosh Root Extract Black cohosh root extract has been extensively studied for its hormone balancing benefits during peri-menopause and menopause. Trans-Resveratrol Resveratrol, a polyphenol found in grapes and red wine, has been shown to have an effect on free radical scavenging and antioxidant properties in various tissues. Trans-resveratrol provides a range of supportive activities including hormonal balance and maintaining normal inflammatory balance. Licorice Root Extract Licorice root is a botanical used medicinally in both Western and Eastern cultures for several thousands of years, and is widely used today in Chinese medicine. The active components of licorice root include glycyrrhizin and isoflavones. Licorice root’s isoflavones have been shown to exert a balancing effect on estrogen levels. Gamma Oryzanol Gamma oryzanol (ferulic acid) is a natural compound extracted from rice bran oil. Gamma oryzanol was first shown to be effective for relieving hot flashes in the early 1960s. Numerous studies have highlighted the benefits of gamma oryzanol for menopausal complaints. Dong Quai Considered by many as the woman’s herb, Dong quai (Angelica sinensis) is native to China and Korea, where it is considered as a “female ginseng” due to its ability to reduce painful menstruation, support a regular and healthy menstrual cycle, and reduce menopausal symptoms, including hot flashes.

CLINICAL APPLICATIONS Supports Healthy Fatty Acid Intake and Eicosanoid Balance Maintains Normal Inflammatory Balance Supports Cardiovascular and Neurological Health Promotes Healthy Skin OVERVIEW Flax seed oil is derived from the seeds of the flax plant, Linum usitatissimum, and is known to be a source of the omega-3 fatty acid, alpha-linolenic acid (ALA). Omega-3 fatty acids are required for a variety of essential body functions, from proper blood flow to brain development. These long chain fatty acids are integral components of tissues and organ systems throughout the body, including the heart, skin, joints, eyes and immune system. Research has shown flax seed oil maintains normal inflammatory balance and promotes cardiovascular and neurological wellness, as well as skin health. Each Flax Seed Oil soft gel includes 1,000 mg of organic flax seed oil, providing high-concentration ALA. Suggested Use: 1-2 soft gel capsules three times per day or as recommended by your health care professional. INGREDIENT BENEFITS Omega-3 Depletion An accumulating body of research shows that the typical Western diet does not provide sufficient amounts of omega-3s required to support optimal health. Inflammatory Balance Flax seed oil has been shown in various studies to maintain normal inflammatory balance throughout the body. Cardiovascular Health Consumption of ALA has been shown to help improve platelet aggregation and the ability of erythrocyte cells to change shape when under stress, resulting in improved circulation throughout the cardiovascular system Skin Health Research has also shown flax seed oil to support various aspects of skin health.

CLINICAL APPLICATIONS Helps Maintain Gastrointestinal Balance in Children Supports Bowel Regularity Enhances Digestion and Micronutrient Absorption OVERVIEW The gastrointestinal tract is a finely balanced environment where roughly 500 different strains of bacteria compete for space and nutrients. The natural microflora balance can be disrupted by medications, such as antibiotics, or poor dietary intake. One of the key benefits of probiotics is their ability to increase populations of healthy bacteria in the face of microflora imbalance. In addition, extensive research has identified other broad health benefits, including supporting healthy bowel function, increasing the production of important short-chain fatty acids, which provide energy to the cells of the intestinal lining, boosting immune function, aiding in the digestion of difficult-to-break-down compounds like lactose and casein, and enhancing detoxification of harmful compounds. Flora Bites is a delicious, chewable probiotic formula for children, designed to promote healthy gut microflora, protect intestinal integrity and support immune function. Each creamy, natural orange-flavored cube contains a 5 billion CFU blend of Lactobacillus acidophilus and Bifidobacterium lactis, as well as 20 mg of vitamin C for comprehensive digestive and immune system support. The strains in Flora Bites have been carefully selected for their survivability and adherence to the intestinal tract. The chewable cube form is an easy, fun way for children to achieve optimal probiotic support and a tasty alternative to a capsule or powdered probiotic. Suggested Use: 1 or more chewable cubes per day or as recommended by your health care professional INGREDIENT BENEFITS Lactobacillus acidophilus Lactobacillus acidophilus is a beneficial bacteria strain normally found in the intestinal tract and mouth, and is commercially used in dairy products for the production of acidophilus-type yogurt. L. acidophilus ferments various carbohydrates to produce lactic acid, which increases the absorption and bioavailability of minerals, including calcium, copper, magnesium and manganese. The production of lactic acid also promotes health by creating an inhospitable environment for invading microbes. L. acidophilus has been shown to protect intestinal cells by competing for adhesion space in the gut against harmful bacteria, such as E. coli. The L. acidophilus strain in Flora Bites has been specifically chosen because of its strong adherence and survival attributes in the GI tract. It has been demonstrated in vitro to tolerate exposure to gastric acid and bile salts, and has the ability to withstand antibiotics including Ciproflaxin, Polymyxin B and Tetracycline. In addition, a study of 73 children (aged 3-24 months, with bouts of occasional diarrhea and mild or moderate dehydration) found those given 10 billion CFU of L. acidophilus had a decreased duration and quantity of watery stools than those receiving placebo. Bifidobacterium lactis (BI-04) Bifidobacterium lactis is predominantly found in the colon. A double-blind, randomized, placebo-controlled trial on subjects receiving B. lactis or placebo for eight weeks found that B. lactis supported a balanced immune response in individuals hypersensitive to environmental allergens. Studies examining immune development and dietary supplementation with B. lactis have shown that it supports GI health by reducing intestinal permeability. A double-blind formula controlled study of 80 infants, aged 6-36 months, were randomly assigned to receive a commercial formula containing B. lactis and Streptococcus thermophilus at the initiation of antibiotics for 15 days. There was a significant difference in the incidence of diarrhea in the children receiving probiotic-supplemented formula (16%) than non-supplemented formula (31%).